The survival and proliferation of fibroblasts on biocomposites containing genetically modified flax fibers: An in vitro study

Annals of Anatomy

Volumn 194, Issue 6, 2012, Pages 513-517

  Kunert Keil, Christiane ^a   Gredes, Tomasz ^a   Meyer, Annelie ^a   Wróbel Kwiatkowska, Magdalena ^b,d   Dominiak, Marzena ^b   Gedrange, Tomasz ^c  

^a UNIVERSITY OF GREIFSWALD   (Germany)

^b WROCLAW MEDICAL UNIVERSITY   (Poland)

^c DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^d UNIVERSITY OF WROC AW   (Poland)

Author keywords

Green composites; In vitro biocompatibility; Polycaprolactone; Polyhydroxybutyrate; Polylactid; Transgenic flax

Indexed keywords

FLAX FIBER; NANOFIBER; POLY(3 HYDROXYBUTYRIC ACID); POLYCAPROLACTONE; POLYLACTID; POLYMER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; COMPOSITE MATERIAL; CONTROLLED STUDY; CYTOTOXICITY; FIBROBLAST; IN VITRO STUDY; INCUBATION TIME; MOLECULAR STABILITY; MOUSE; NONHUMAN;

ANIMALS; BIOCOMPATIBLE MATERIALS; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; FIBROBLASTS; FLAX; MATERIALS TESTING; MICE; PLANTS, GENETICALLY MODIFIED; TISSUE SCAFFOLDS;

LINUM USITATISSIMUM; MUS;

EID: 84869497585     PISSN: 09409602     EISSN: 16180402     Source Type: Journal    
DOI: 10.1016/j.aanat.2011.12.006     Document Type: Article

References (30)

1. Ashammakhi N., Suuronen R., Tiainen J., Tormala P., Waris T. Spotlight on naturally absorbable osteofixation devices. J. Craniofac. Surg. 2003, 14:247-259.
2. Bax B., Müssig J. Impact and tensile properties of PLA/Cordenka and PLA/flax composites. Compos. Sci. Technol. 2008, 68:1601-1607.
3. Chen G., Zhou P., Mei N., Chen X., Shao Z., Pan L., Wu C. Silk fibroin modified porous poly(epsilon-caprolactone) scaffold for human fibroblast culture in vitro. J. Mater. Sci. Mater. Med. 2004, 15:671-677.
4. Fuse M., Hayakawa T., Kozaki M., Ishikura K., Ichimura M., Tsuzukibashi O., Fukatsu A., Fukumoto M., Makimura M. Attachment of human gingival fibroblasts onto collagen PLA porous scaffold. J. Jpn. Assoc. Regenerative Dent. 2009, 7:1-9.
5. Garric X., Moles J.P., Garreau H., Guilhou J.J., Vert M. Human skin cell cultures onto PLA50 (PDLLA) bioresorbable polymers: influence of chemical and morphological surface modifications. J. Biomed. Mater. Res. A 2005, 72:180-189.
6. Gredes T., Spassov A., Mai R., Mack H., Loster B.W., Mazurkiewicz-Janik M., Kubein-Meesenburg D., Fanghanel J., Gedrange T. Changes in insulin like growth factors, myostatin and vascular endothelial growth factor in rat musculus latissimus dorsi by poly-3-hydroxybutyrate implants. J. Physiol. Pharmacol. 2009, 60(Suppl. 3):77-81.
7. Hayashi T., Kawai T., Ishikawa A., Kawai H., Nakano K., Takei Y., Kuroki K. Histological analysis of induced cartilage on the biodegradable or nonbiodegradable membranes from immature muscular tissue in vitro. J. Biomed. Mater. Res. A 2008, 86:1048-1054.
8. Holzl F., Pfannschmidt O., Manegold E., Rohrmann D., Jakse G., Brauers A. In vitro analysis and animal experiment study of surface modified biodegradable polylactide ureteral stents. Urologe A 2000, 39:557-564.
9. Ishaug S.L., Yaszemski M.J., Bizios R., Mikos A.G. Osteoblast function on synthetic biodegradable polymers. J. Biomed. Mater. Res. 1994, 28:1445-1453.
10. Iwamatsu-Kobayashi Y., Nishihara D., Hirata M., Kindaichi K., Komatsu M. Effects of biomaterials on cell adhesion of human peridontal ligament fibroblasts and fibronectin absorption. Int. Congr. Ser. 2005, 1284:334-335.
11. Jarosz-Cichulska H. Studies on perfecting Polish-made linen threads for surgical use. Polim. Med. 1988, 18:3-49.
12. Jhala A.J., Weselake R.J., Hall L.M. Genetically engineered flax; potential benefits, risks, regulations, and mitigation of transgene movement. Crop Sci. 2009, 49:1943-1954.
13. Khor H.L., Ng K.W., Htay A.S., Schantz J.T., Teoh S.H., Hutmacher D.W. Preliminary study of a polycaprolactone membrane utilized as epidermal substrate. J. Mater. Sci. Mater. Med. 2003, 14:113-120.
14. Kiremitci M., Piskin E. Cell adhesion to the surfaces of polymeric beads. Biomater. Artif. Cells Artif. Organs 1990, 18:599-603.
15. Kraitzer A., Kloog Y., Zilberman M. Novel farnesylthiosalicylate (FTS)-eluting composite structures. Eur. J. Pharm. Sci. 2009, 37:351-362.
16. Lee S.J., Khang G., Lee Y.M., Lee H.B. Interaction of human chondrocytes and NIH/3T3 fibroblasts on chloric acid-treated biodegradable polymer surfaces. J. Biomater. Sci. Polym. Ed. 2002, 13:197-212.
17. Mack H.B., Mai R., Lauer G., Mack F., Gedrange T., Franke R., Gredes T. Adaptation of myosin heavy chain mRNA expression after implantation of poly(3)hydroxybutyrate scaffolds in rat m. latissimus dorsi. J. Physiol. Pharmacol. 2008, 59(Suppl. 5):95-103.
18. Mohanty A.K., Misra M., Drzal L.T. Natural Fibers Biopolymers and Biocomposites 2005, CRC Press, Boca Raton.
19. Rimondini L., Nicoli-Aldini N., Fini M., Guzzardella G., Tschon M., Giardino R. In vivo experimental study on bone regeneration in critical bone defects using an injectable biodegradable PLA/PGA copolymer. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 2005, 99:148-154.
20. Schantz J.T., Hutmacher D.W., Ng K.W., Khor H.L., Lim M.T., Teoh S.H. Evaluation of a tissue-engineered membrane-cell construct for guided bone regeneration. Int. J. Oral Maxillofac. Implants 2002, 17:161-174.
21. Shishatskaya E.I., Voinova O.N., Goreva A.V., Mogilnaya O.A., Volova T.G. Biocompatibility of polyhydroxybutyrate microspheres: in vitro and in vivo evaluation. J. Mater. Sci. Mater. Med. 2008, 19:2493-2502.
22. Skorkowska-Telichowska K., Zuk M., Kulma A., Bugajska-Prusak A., Ratajczak K., Gasiorowski K., Kostyn K., Szopa J. New dressing materials derived from transgenic flax products to treat long-standing venuos ulcers-a pilot study. Wound Repair Regen. 2010, 578:1-11.
23. Szopa J., Wrobel-Kwiatkowska M., Kulma A., Zuk M., Skorkowska-Telichowska K., Dyminska L., Maczka M., Hanusa J., Zebrowski J., Preisner M. Chemical composition and molecular structure of fibers from transgenic flax producing polyhydroxybutyrate, and mechanical properties and platelet aggregation of composite materials containing these fibers. Compos. Sci. Technol. 2009, 69:2438-2446.
24. Tolkachev O.N., Zhuchenko A.A. Biologically active substances of flax: medicinal and nutritional properties (a review). Pharm. Chem. J. 2000, 34:360-367.
25. van Dam J.E.G., van Vilsteren G.E.T., Zomers F.H.A., Shannon W.E., Hamilton I.T. Increased application of domestically produced plant fibres in textile, pulp and paper production, and composite materials. Industrial Fiber Crops, European Commission Directorate-General XII 1996.
26. Vance R.J., Miller D.C., Thapa A., Haberstroh K.M., Webster T.J. Decreased fibroblast cell density on chemically degraded poly-lactic-co-glycolic acid, polyurethane, and polycaprolactone. Biomaterials 2004, 25:2095-2103.
27. Vunjak-Novakovic G., Obradovic B., Martin I., Bursac P.M., Langer R., Freed L.E. Dynamic cell seeding of polymer scaffolds for cartilage tissue engineering. Biotechnol. Prog. 1998, 14:193-202.
28. Wrobel-Kwiatkowska M., Zebrowski J., Starzycki M., Oszmianski J., Szopa J. Engineering of PHB synthesis causes improved elastic properties of flax fibers. Biotechnol. Prog. 2007, 23:269-277.
29. Wrobel M., Zebrowski J., Szopa J. Polyhydroxybutyrate synthesis in transgenic flax. J. Biotechnol. 2004, 107:41-54.
30. Zhu Y., Gao C., Shen J. Surface modification of polycaprolactone with poly(methacrylic acid) and gelatin covalent immobilization for promoting its cytocompatibility. Biomaterials 2002, 23:4889-4895.