Neonatal isolation decreases cued fear conditioning and frontal cortical histone 3 lysine 9 methylation in adult female rats

European Journal of Pharmacology

Volumn 697, Issue 1-3, 2012, Pages 65-72

  Kao, Gour Shenq ^a   Cheng, Ling Yi ^a   Chen, Li Hsien ^a   Tzeng, Wen Yu ^a   Cherng, Chienfang G ^b   Su, Chien Chou ^a   Wang, Ching Yi ^a   Yu, Lung ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b CHANG JUNG CHRISTIAN UNIVERSITY   (Taiwan)

Author keywords

Cued fear memory; Early life stress; Epigenetic modulation; Frontal cortex; Histone deacetylase inhibitor; Valproic acid

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; CORTICOSTERONE; ESTRADIOL; HISTONE H3; LYSINE; VALPROIC ACID;

ACOUSTIC REFLEX; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASSOCIATION; BEHAVIOR CHANGE; CONDITIONING; CONTROLLED STUDY; CORTICOSTERONE RELEASE; DNA MODIFICATION; EPIGENETICS; ESTRADIOL BLOOD LEVEL; FEAR; FEMALE; FRONTAL CORTEX; HISTONE ACETYLATION; HISTONE METHYLATION; HORMONE RESPONSE; LIFE STRESS; MALE; MOTHER CHILD RELATION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PUERPERIUM; RAT; SEPARATION ANXIETY; SIBLING; STARTLE REFLEX;

ACOUSTIC STIMULATION; AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; AZACITIDINE; BEHAVIOR, ANIMAL; CEREBRAL CORTEX; CONDITIONING (PSYCHOLOGY); CORTICOSTERONE; CUES; DNA MODIFICATION METHYLASES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ESTRADIOL; FEAR; FEMALE; HISTONE DEACETYLASE INHIBITORS; HISTONES; LIGHT; LYSINE; MATERNAL DEPRIVATION; METHYLATION; PHOTIC STIMULATION; RATS; RATS, SPRAGUE-DAWLEY; STARTLE REACTION; STRESS, PSYCHOLOGICAL; VALPROIC ACID;

EID: 84869493425     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.09.040     Document Type: Article

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