Adenomatoid Odontogenic Tumor: Retrospective Study of 15 Cases with Emphasis on Histopathologic Features

Head and Neck Pathology

Volumn 6, Issue 4, 2012, Pages 430-437

  de Matos, Felipe Rodrigues ^a   Nonaka, Cassiano Francisco Weege ^a   Pinto, Leão Pereira ^a   de Souza, Lélia Batista ^a   de Almeida Freitas, Roseana ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE   (Brazil)

Author keywords

Adenomatoid odontogenic tumor; Clinical; Histopathology; Odontogenic tumor

Indexed keywords

ADENOMA; ADOLESCENT; ARTICLE; FEMALE; HUMAN; JAW TUMOR; MALE; ODONTOGENIC TUMOR; PATHOLOGY; RETROSPECTIVE STUDY;

ADENOMA; ADOLESCENT; FEMALE; HUMANS; JAW NEOPLASMS; MALE; ODONTOGENIC TUMORS; RETROSPECTIVE STUDIES;

EID: 84869492929     PISSN: 1936055X     EISSN: 19360568     Source Type: Journal    
DOI: 10.1007/s12105-012-0388-x     Document Type: Article

References (39)

1. Vera Sempere FJ, Artes Martinez MJ, Vera Sirera B, Bonet Marco J. Follicular adenomatoid odontogenic tumor: immunohistochemical study. Med Oral Patol Oral Cir Bucal. 2006; 11(4): E305-8.
2. Philipsen HP, Reichart PA. Adenomatoid odontogenic tumour: facts and figures. Oral Oncol. 1999; 35(2): 125-31.
3. Harbitz F. On cystic tumors of the maxilla, and especially on adamantine cystadenomas (adamantomas). Dent Cosmos. 1915; 57: 1081-93.
4. Philipsen HP, Reichart PA, Siar CH, Ng KH, Lau SH, Zhang X, et al. An updated clinical and epidemiological profile of the adenomatoid odontogenic tumour: a collaborative retrospective study. J Oral Pathol Med. 2007; 36(7): 383-93.
5. Philipsen HP, Birn H. The adenomatoid odontogenic tumour. Ameloblastic adenomatoid tumour or adeno-ameloblastoma. Acta Pathol Microbiol Scand. 1969; 75(3): 375-98.
6. Pindborg JJ, Kramer JR, Torloni H. Histological typing of odontogenic tumours, jaw cysts and allied lesions. Geneva: WHO; 1971.
7. Mohamed A, Singh AS, Raubenheimer EJ, Bouckaert MM. Adenomatoid odontogenic tumour: review of the literature and an analysis of 33 cases from South Africa. Int J Oral Maxillofac Surg. 2010; 39(9): 843-6.
8. Leon JE, Mata GM, Fregnani ER, Carlos-Bregni R, de Almeida OP, Mosqueda-Taylor A, et al. Clinicopathological and immunohistochemical study of 39 cases of Adenomatoid Odontogenic Tumour: a multicentric study. Oral Oncol. 2005; 41(8): 835-42.
9. Swasdison S, Dhanuthai K, Jainkittivong A, Philipsen HP. Adenomatoid odontogenic tumors: an analysis of 67 cases in a Thai population. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008; 105(2): 210-5.
10. Philipsen HP, Reichart PA, Zhang KH, Nikai H, Yu QX. Adenomatoid odontogenic tumor: biologic profile based on 499 cases. J Oral Pathol Med. 1991; 20(4): 149-58.
11. Mendis BR, MacDonald DG. Adenomatoid odontogenic tumour. A survey of 21 cases from Sri Lanka. Int J Oral Maxillofac Surg. 1990; 19(3): 141-3.
12. Arotiba GT, Arotiba JT, Olaitan AA, Ajayi OF. The adenomatoid odontogenic tumor: an analysis of 57 cases in a black African population. J Oral Maxillofac Surg 1997; 55(2): 146-8; discussion 9-50.
13. Takahashi H, Fujita S, Shibata Y, Yamaguchi A. Adenomatoid odontogenic tumour: immunohistochemical demonstration of transferrin, ferritin and alpha-one-antitrypsin. J Oral Pathol Med. 2001; 30(4): 237-44.
14. Jivan V, Altini M, Meer S. Secretory cells in adenomatoid odontogenic tumour: tissue induction or metaplastic mineralisation? Oral Dis. 2008; 14(5): 445-9.
15. Philipsen HP, Nikai H. Chapter 6: odontogenic tumours, adenomatoid odontogenic tumour. In: Pathology and genetics of head and neck tumours. Lyon, France: IARC Press; 2005. p. 304-5.
16. Gadewar DR, Srikant N. Adenomatoid odontogenic tumour: tumour or a cyst, a histopathological support for the controversy. Int J Pediatr Otorhinolaryngol. 2010; 74(4): 333-7.
17. el-Labban NG, Lee KW. Vascular degeneration in adenomatoid odontogenic tumour: an ultrastructural study. J Oral Pathol 1988; 17(6): 298-305.
18. Rick GM. Adenomatoid odontogenic tumor. Oral Maxillofac Surg Clin North Am. 2004; 16(3): 333-54.
19. Santos JN, Lima FO, Romerio P, Souza VF. Adenomatoid odontogenic tumor: an unusual case exhibiting cribriform aspect. Quintessence Int. 2008; 39(9): 777-81.
20. Barnes L, Eveson JW, Reichart P, Sidransky D. World health organization classification of tumours. Pathology and genetics of head and neck tumours. Lyon: IARC Press; 2005.
21. Yamamoto H, Kozawa Y, Hirai G, Hagiwara T, Nakamura T. Adenomatoid odontogenic tumor: light and electron microscopic study. Int J Oral Surg. 1981; 10(4): 272-8.
22. Philipsen HP, Reichart PA, Nikai H. The adenomatoid odontogenic tumour (AOT): an update. Oral Med Pathol. 1997; 2: 55-60.
23. Philipsen HP, Samman N, Ormiston IW, Wu PC, Reichart PA. Variants of the adenomatoid odontogenic tumor with a note on tumor origin. J Oral Pathol Med. 1992; 21(8): 348-52.
24. Poulson TC, Greer RO Jr. Adenomatoid odontogenic tumor: clinicopathologic and ultrastructural concepts. J Oral Maxillofac Surg. 1983; 41(12): 818-24.
25. Crivelini MM, de Araujo VC, de Sousa SO, de Araujo NS. Cytokeratins in epithelia of odontogenic neoplasms. Oral Dis. 2003; 9(1): 1-6.
26. Murata M, Cheng J, Horino K, Hara K, Shimokawa H, Saku T. Enamel proteins and extracellular matrix molecules are co-localized in the pseudocystic stromal space of adenomatoid odontogenic tumor. J Oral Pathol Med. 2000; 29(10): 483-90.
27. Saku T, Okabe H, Shimokawa H. Immunohistochemical demonstration of enamel proteins in odontogenic tumors. J Oral Pathol Med. 1992; 21(3): 113-9.
28. Takata T, Zhao M, Uchida T, Kudo Y, Sato S, Nikai H. Immunohistochemical demonstration of an enamel sheath protein, sheathlin, in odontogenic tumors. Virchows Arch. 2000; 436(4): 324-9.
29. Tajima Y, Sakamoto E, Yamamoto Y. Odontogenic cyst giving rise to an adenomatoid odontogenic tumor: report of a case with peculiar features. J Oral Maxillofac Surg. 1992; 50(2): 190-3.
30. Takeda Y. Induction of osteodentin and abortive enamel in adenomatoid odontogenic tumor. Ann Dent. 1995; 54(1-2): 61-3.
31. Zeitoun IM, Dhanrajani PJ, Mosadomi HA. Adenomatoid odontogenic tumor arising in a calcifying odontogenic cyst. J Oral Maxillofac Surg. 1996; 54(5): 634-7.
32. Dunlap CL, Fritzlen TJ. Cystic odontoma with concomitant adenoameloblastoma (adenoameloblastic odontoma). Oral Surg Oral Med Oral Pathol. 1972; 34(3): 450-6.
33. Mosqueda-Taylor A, Carlos-Bregni R, Ledesma-Montes C, Fillipi RZ, de Almeida OP, Vargas PA. Calcifying epithelial odontogenic tumor-like areas are common findings in adenomatoid odontogenic tumors and not a specific entity. Oral Oncol. 2005; 41(2): 214-5.
34. Ledesma-Montes C, Mosqueda-Taylor A, Romero de León E, de la Piedra Garza M, Goldberg Juakin P, Portilla Robertson J. Adenomatoid odontogenic tumor with features of calcifying epithelial odontogenic tumor. (The so-called combined epithelial odontogenic tumor) Clinico-pathological report of 12 cases. Eur J Cancer B Oral Oncol. 1993; 29B: 221-4.
35. Lawson W, Abaci IF, Zak FG. Studies on melanocytes. V. The presence of melanocytes in the human dental primordium: an explanation for pigmented lesions of the jaws. Oral Surg Oral Med Oral Pathol. 1976; 42(3): 375-80.
36. Aldred MJ, Gray AR. A pigmented adenomatoid odontogenic tumor. Oral Surg Oral Med Oral Pathol. 1990; 70(1): 86-9.
37. Warter A, George-Diolombi G, Chazal M, Ango A. Melanin in a dentigerous cyst and associated adenomatoid odontogenic tumor. Cancer. 1990; 66(4): 786-8.
38. Takeda Y. Pigmented adenomatoid odontogenic tumour. Report of an undescribed case and review of the literature of pigmented intraosseous odontogenic lesions. Virchows Arch A Pathol Anat Histopathol. 1989; 415(6): 571-5.
39. Effiom OA, Odukoya O. Adenomatoid odontogenic tumour: a clinico-pathological analysis and melanin pigmentation study of 31 Nigerian cases. Niger Postgrad Med J. 2005; 12(2): 131-5.