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Volumn 132, Issue 2, 2013, Pages 485-494

An armed oncolytic herpes simplex virus expressing thrombospondin-1 has an enhanced in vivo antitumor effect against human gastric cancer

Author keywords

antiangiogenesis; gastric cancer; herpes simplex virus; oncolytic virus; thrombospondin 1

Indexed keywords

ONCOLYTIC HERPES VIRUS; ONCOLYTIC VIRUS; T 01; THROMBOSPONDIN 1; UNCLASSIFIED DRUG;

EID: 84869492617     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.27681     Document Type: Article
Times cited : (38)

References (43)
  • 3
    • 12944272092 scopus 로고    scopus 로고
    • Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma
    • Rampling R, Cruickshank G, Papanastassiou V, et al. Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma. Gene Ther 2000; 7: 859-66.
    • (2000) Gene Ther , vol.7 , pp. 859-866
    • Rampling, R.1    Cruickshank, G.2    Papanastassiou, V.3
  • 4
    • 12944315014 scopus 로고    scopus 로고
    • Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: Results of a phase i trial
    • Markert JM, Medlock MD, Rabkin SD, et al. Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial. Gene Ther 2000; 7: 867-74.
    • (2000) Gene Ther , vol.7 , pp. 867-874
    • Markert, J.M.1    Medlock, M.D.2    Rabkin, S.D.3
  • 5
    • 33845731246 scopus 로고    scopus 로고
    • Phase I, open-label, dose-escalating study of a genetically engineered herpes simplex virus, NV1020, in subjects with metastatic colorectal carcinoma to the liver
    • Kemeny N, Brown K, Covey A, et al. Phase I, open-label, dose-escalating study of a genetically engineered herpes simplex virus, NV1020, in subjects with metastatic colorectal carcinoma to the liver. Hum Gene Ther 2006; 17: 1214-24.
    • (2006) Hum Gene Ther , vol.17 , pp. 1214-1224
    • Kemeny, N.1    Brown, K.2    Covey, A.3
  • 6
    • 33845336115 scopus 로고    scopus 로고
    • A phase i study of OncoVEXGM-CSF, a second-generation oncolytic herpes simplex virus expressing granulocyte macrophage colony-stimulating factor
    • Hu JC, Coffin RS, Davis CJ, et al. A phase I study of OncoVEXGM-CSF, a second-generation oncolytic herpes simplex virus expressing granulocyte macrophage colony-stimulating factor. Clin Cancer Res 2006; 12: 6737-47.
    • (2006) Clin Cancer Res , vol.12 , pp. 6737-6747
    • Hu, J.C.1    Coffin, R.S.2    Davis, C.J.3
  • 7
    • 77149141965 scopus 로고    scopus 로고
    • Local and distant immunity induced by intralesional vaccination with an oncolytic herpes virus encoding GM-CSF in patients with stage IIIc and IV melanoma
    • Kaufman HL, Kim DW, DeRaffele G, et al. Local and distant immunity induced by intralesional vaccination with an oncolytic herpes virus encoding GM-CSF in patients with stage IIIc and IV melanoma. Ann Surg Oncol 2010; 17: 718-30.
    • (2010) Ann Surg Oncol , vol.17 , pp. 718-730
    • Kaufman, H.L.1    Kim, D.W.2    Deraffele, G.3
  • 8
    • 0038492868 scopus 로고    scopus 로고
    • Effective therapy of metastatic ovarian cancer with an oncolytic herpes simplex virus incorporating two membrane fusion mechanisms
    • Nakamori M, Fu X, Meng F, et al. Effective therapy of metastatic ovarian cancer with an oncolytic herpes simplex virus incorporating two membrane fusion mechanisms. Clin Cancer Res 2003; 9: 2727-33.
    • (2003) Clin Cancer Res , vol.9 , pp. 2727-2733
    • Nakamori, M.1    Fu, X.2    Meng, F.3
  • 9
    • 2442661484 scopus 로고    scopus 로고
    • Destruction of nonimmunogenic mammary tumor cells by a fusogenic oncolytic herpes simplex virus induces potent antitumor immunity
    • Nakamori M, Fu X, Rousseau R, et al. Destruction of nonimmunogenic mammary tumor cells by a fusogenic oncolytic herpes simplex virus induces potent antitumor immunity. Mol Ther 2004; 9: 658-65.
    • (2004) Mol Ther , vol.9 , pp. 658-665
    • Nakamori, M.1    Fu, X.2    Rousseau, R.3
  • 10
    • 2442710168 scopus 로고    scopus 로고
    • Potent antitumor activity after systemic delivery of a doubly fusogenic oncolytic herpes simplex virus against metastatic prostate cancer
    • Nakamori M, Fu X, Pettaway CA, et al. Potent antitumor activity after systemic delivery of a doubly fusogenic oncolytic herpes simplex virus against metastatic prostate cancer. Prostate 2004; 60: 53-60.
    • (2004) Prostate , vol.60 , pp. 53-60
    • Nakamori, M.1    Fu, X.2    Pettaway, C.A.3
  • 11
    • 0035933088 scopus 로고    scopus 로고
    • Oncolytic herpes simplex virus vector with enhanced MHC class i presentation and tumor cell killing
    • Todo T, Martuza RL, Rabkin SD, et al. Oncolytic herpes simplex virus vector with enhanced MHC class I presentation and tumor cell killing. Proc Natl Acad Sci USA 2001; 98: 6396-401.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6396-6401
    • Todo, T.1    Martuza, R.L.2    Rabkin, S.D.3
  • 12
    • 33846707286 scopus 로고    scopus 로고
    • Angiogenic response caused by oncolytic herpes simplex virus-induced reduced thrombospondin expression can be prevented by specific viral mutations or by administering a thrombospondin-derived peptide
    • Aghi M, Rabkin SD, Martuza RL,. Angiogenic response caused by oncolytic herpes simplex virus-induced reduced thrombospondin expression can be prevented by specific viral mutations or by administering a thrombospondin-derived peptide. Cancer Res 2007; 67: 440-4.
    • (2007) Cancer Res , vol.67 , pp. 440-444
    • Aghi, M.1    Rabkin, S.D.2    Martuza, R.L.3
  • 13
    • 48349119172 scopus 로고    scopus 로고
    • Oncolytic HSV-1 infection of tumors induces angiogenesis and upregulates CYR61
    • Kurozumi K, Hardcastle J, Thakur R, et al. Oncolytic HSV-1 infection of tumors induces angiogenesis and upregulates CYR61. Mol Ther 2008; 16: 1382-91.
    • (2008) Mol Ther , vol.16 , pp. 1382-1391
    • Kurozumi, K.1    Hardcastle, J.2    Thakur, R.3
  • 14
    • 0028609624 scopus 로고
    • Transfection of thrombospondin 1 complementary DNA into a human breast carcinoma cell line reduces primary tumor growth, metastatic potential, and angiogenesis
    • Weinstat-Saslow DL, Zabrenetzky VS, VanHoutte K, et al. Transfection of thrombospondin 1 complementary DNA into a human breast carcinoma cell line reduces primary tumor growth, metastatic potential, and angiogenesis. Cancer Res 1994; 54: 6504-11.
    • (1994) Cancer Res , vol.54 , pp. 6504-6511
    • Weinstat-Saslow, D.L.1    Zabrenetzky, V.S.2    Vanhoutte, K.3
  • 15
    • 0029151154 scopus 로고
    • Thrombospondin 1 expression in transformed endothelial cells restores a normal phenotype and suppresses their tumorigenesis
    • Sheibani N, Frazier WA,. Thrombospondin 1 expression in transformed endothelial cells restores a normal phenotype and suppresses their tumorigenesis. Proc Natl Acad Sci USA 1995; 92: 6788-92.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 6788-6792
    • Sheibani, N.1    Frazier, W.A.2
  • 16
    • 0030893967 scopus 로고    scopus 로고
    • Sequential development of an angiogenic phenotype by human fibroblasts progressing to tumorigenicity
    • Volpert OV, Dameron KM, Bouck N,. Sequential development of an angiogenic phenotype by human fibroblasts progressing to tumorigenicity. Oncogene 1997; 14: 1495-502.
    • (1997) Oncogene , vol.14 , pp. 1495-1502
    • Volpert, O.V.1    Dameron, K.M.2    Bouck, N.3
  • 17
    • 0030833817 scopus 로고    scopus 로고
    • CD36 mediates the in vitro inhibitory effects of thrombospondin-1 on endothelial cells
    • Dawson DW, Pearce SF, Zhong R, et al. CD36 mediates the In vitro inhibitory effects of thrombospondin-1 on endothelial cells. J Cell Biol 1997; 138: 707-17.
    • (1997) J Cell Biol , vol.138 , pp. 707-717
    • Dawson, D.W.1    Pearce, S.F.2    Zhong, R.3
  • 18
    • 0842325791 scopus 로고    scopus 로고
    • CD47 mediates killing of breast tumor cells via Gi-dependent inhibition of protein kinase A
    • Manna PP, Frazier WA,. CD47 mediates killing of breast tumor cells via Gi-dependent inhibition of protein kinase A. Cancer Res 2004; 64: 1026-36.
    • (2004) Cancer Res , vol.64 , pp. 1026-1036
    • Manna, P.P.1    Frazier, W.A.2
  • 19
    • 22144442812 scopus 로고    scopus 로고
    • Type 3 repeat/C-terminal domain of thrombospondin-1 triggers caspase-independent cell death through CD47/alphavbeta3 in promyelocytic leukemia NB4 cells
    • Saumet A, Slimane MB, Lanotte M, et al. Type 3 repeat/C-terminal domain of thrombospondin-1 triggers caspase-independent cell death through CD47/alphavbeta3 in promyelocytic leukemia NB4 cells. Blood 2005; 106: 658-67.
    • (2005) Blood , vol.106 , pp. 658-667
    • Saumet, A.1    Slimane, M.B.2    Lanotte, M.3
  • 20
    • 3242799579 scopus 로고    scopus 로고
    • Expression of the type-1 repeats of thrombospondin-1 inhibits tumor growth through activation of transforming growth factor-β
    • Yee KO, Streit M, Hawighorst T, et al. Expression of the type-1 repeats of thrombospondin-1 inhibits tumor growth through activation of transforming growth factor-β. Am J Pathol 2004; 165: 541-52.
    • (2004) Am J Pathol , vol.165 , pp. 541-552
    • Yee, K.O.1    Streit, M.2    Hawighorst, T.3
  • 21
    • 0035940429 scopus 로고    scopus 로고
    • Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor
    • Rodriguez-Manzaneque JC, Lane TF, Ortega MA, et al. Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor. Proc Natl Acad Sci USA 2001; 98: 12485-90.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 12485-12490
    • Rodriguez-Manzaneque, J.C.1    Lane, T.F.2    Ortega, M.A.3
  • 22
    • 76349108532 scopus 로고    scopus 로고
    • Enhanced antitumor efficacy of vasculostatin (Vstat120) expressing oncolytic HSV-1
    • Hardcastle J, Kurozumi K, Dmitrieva N, et al. Enhanced antitumor efficacy of vasculostatin (Vstat120) expressing oncolytic HSV-1. Mol Ther 2009; 18: 285-94.
    • (2009) Mol Ther , vol.18 , pp. 285-294
    • Hardcastle, J.1    Kurozumi, K.2    Dmitrieva, N.3
  • 23
    • 77949621084 scopus 로고    scopus 로고
    • The thrombospondin-1 mimetic ABT-510 increases the uptake and effectiveness of cisplatin and paclitaxel in a mouse model of epithelial ovarian cancer
    • Campbell NE, Greenaway J, Henkin J, et al. The thrombospondin-1 mimetic ABT-510 increases the uptake and effectiveness of cisplatin and paclitaxel in a mouse model of epithelial ovarian cancer. Neoplasia 2010; 12: 275-83.
    • (2010) Neoplasia , vol.12 , pp. 275-283
    • Campbell, N.E.1    Greenaway, J.2    Henkin, J.3
  • 24
    • 28244502278 scopus 로고    scopus 로고
    • Triple gene-deleted oncolytic herpes simplex virus vector double-armed with interleukin 18 and soluble B7-1 constructed by bacterial artificial chromosome-mediated system
    • Fukuhara H, Ino Y, Kuroda T, et al. Triple gene-deleted oncolytic herpes simplex virus vector double-armed with interleukin 18 and soluble B7-1 constructed by bacterial artificial chromosome-mediated system. Cancer Res 2005; 65: 10663-8.
    • (2005) Cancer Res , vol.65 , pp. 10663-10668
    • Fukuhara, H.1    Ino, Y.2    Kuroda, T.3
  • 25
    • 33845295448 scopus 로고    scopus 로고
    • Dominant-negative fibroblast growth factor receptor expression enhances antitumoral potency of oncolytic herpes simplex virus in neural tumors
    • Liu TC, Zhang T, Fukuhara H, et al. Dominant-negative fibroblast growth factor receptor expression enhances antitumoral potency of oncolytic herpes simplex virus in neural tumors. Clin Cancer Res 2006; 12: 6791-9.
    • (2006) Clin Cancer Res , vol.12 , pp. 6791-6799
    • Liu, T.C.1    Zhang, T.2    Fukuhara, H.3
  • 26
    • 0037598911 scopus 로고    scopus 로고
    • Expression of a fusogenic membrane glycoprotein by an oncolytic herpes simplex virus potentiates the viral antitumor effect
    • Fu X, Tao L, Jin A, et al. Expression of a fusogenic membrane glycoprotein by an oncolytic herpes simplex virus potentiates the viral antitumor effect. Mol Ther 2003; 7: 748-54.
    • (2003) Mol Ther , vol.7 , pp. 748-754
    • Fu, X.1    Tao, L.2    Jin, A.3
  • 27
    • 80054748674 scopus 로고    scopus 로고
    • Virotherapy induces massive infiltration of neutrophils in a subset of tumors defined by a strong endogenous interferon response activity
    • Fu X, Tao L, Rivera A, et al. Virotherapy induces massive infiltration of neutrophils in a subset of tumors defined by a strong endogenous interferon response activity. Cancer Gene Ther 2011; 18: 785-94.
    • (2011) Cancer Gene Ther , vol.18 , pp. 785-794
    • Fu, X.1    Tao, L.2    Rivera, A.3
  • 28
    • 34447262594 scopus 로고    scopus 로고
    • Antitumor effects of two newly constructed oncolytic herpes simplex viruses against renal cell carcinoma
    • Fu X, Nakamori M, Tao L, et al. Antitumor effects of two newly constructed oncolytic herpes simplex viruses against renal cell carcinoma. Int J Oncol 2007; 30: 1561-7.
    • (2007) Int J Oncol , vol.30 , pp. 1561-1567
    • Fu, X.1    Nakamori, M.2    Tao, L.3
  • 29
    • 0034658412 scopus 로고    scopus 로고
    • Thrombospondin-1 is downregulated by anoxia and suppresses tumorigenicity of human glioblastoma cells
    • Tenan M, Fulci G, Albertoni M, et al. Thrombospondin-1 is downregulated by anoxia and suppresses tumorigenicity of human glioblastoma cells. J Exp Med 2000; 191: 1789-98.
    • (2000) J Exp Med , vol.191 , pp. 1789-1798
    • Tenan, M.1    Fulci, G.2    Albertoni, M.3
  • 30
    • 31144449762 scopus 로고    scopus 로고
    • Wnt signaling can repress thrombospondin-1 expression in colonic tumorigenesis
    • Jo WS, Mizukami Y, Duerr EM, et al. Wnt signaling can repress thrombospondin-1 expression in colonic tumorigenesis. Cancer Biol Ther 2005; 4: 1361-6.
    • (2005) Cancer Biol Ther , vol.4 , pp. 1361-1366
    • Jo, W.S.1    Mizukami, Y.2    Duerr, E.M.3
  • 31
    • 25444455101 scopus 로고    scopus 로고
    • Suppression of thrombospondin 1 and 2 production by herpes simplex virus 1 infection in cultured keratocytes
    • Choudhary A, Hiscott P, Hart CA, et al. Suppression of thrombospondin 1 and 2 production by herpes simplex virus 1 infection in cultured keratocytes. Mol Vis 2005; 11: 163-8.
    • (2005) Mol Vis , vol.11 , pp. 163-168
    • Choudhary, A.1    Hiscott, P.2    Hart, C.A.3
  • 32
    • 0032770860 scopus 로고    scopus 로고
    • Overexpression of thrombospondin-1 decreases angiogenesis and inhibits the growth of human cutaneous squamous cell carcinomas
    • Streit M, Velasco P, Brown LF, et al. Overexpression of thrombospondin-1 decreases angiogenesis and inhibits the growth of human cutaneous squamous cell carcinomas. Am J Pathol 1999; 155: 441-52.
    • (1999) Am J Pathol , vol.155 , pp. 441-452
    • Streit, M.1    Velasco, P.2    Brown, L.F.3
  • 33
    • 58149521990 scopus 로고    scopus 로고
    • ABT-510 induces tumor cell apoptosis and inhibits ovarian tumor growth in an orthotopic, syngeneic model of epithelial ovarian cancer
    • Greenaway J, Henkin J, Lawler J, et al. ABT-510 induces tumor cell apoptosis and inhibits ovarian tumor growth in an orthotopic, syngeneic model of epithelial ovarian cancer. Mol Cancer Ther 2009; 8: 64-74.
    • (2009) Mol Cancer Ther , vol.8 , pp. 64-74
    • Greenaway, J.1    Henkin, J.2    Lawler, J.3
  • 34
    • 0035503689 scopus 로고    scopus 로고
    • Thrombospondin-1 type 1 repeat recombinant proteins inhibit tumor growth through transforming growth factor-beta-dependent and -independent mechanisms
    • Miao WM, Seng WL, Duquette M, et al. Thrombospondin-1 type 1 repeat recombinant proteins inhibit tumor growth through transforming growth factor-beta-dependent and -independent mechanisms. Cancer Res 2001; 61: 7830-9.
    • (2001) Cancer Res , vol.61 , pp. 7830-7839
    • Miao, W.M.1    Seng, W.L.2    Duquette, M.3
  • 35
    • 77956933263 scopus 로고    scopus 로고
    • A third-generation herpesvirus is effective against gastroesophageal cancer
    • Wong J, Kelly K, Mittra A, et al. A third-generation herpesvirus is effective against gastroesophageal cancer. J Surg Res 2010; 163: 214-20.
    • (2010) J Surg Res , vol.163 , pp. 214-220
    • Wong, J.1    Kelly, K.2    Mittra, A.3
  • 36
    • 80052969634 scopus 로고    scopus 로고
    • Effect of a caspase inhibitor, zVADfmk, on the inhibition of breast cancer cells by herpes simplex virus type 1
    • Wood LW, Shillitoe EJ,. Effect of a caspase inhibitor, zVADfmk, on the inhibition of breast cancer cells by herpes simplex virus type 1. Cancer Gene Ther 2011; 18: 685-94.
    • (2011) Cancer Gene Ther , vol.18 , pp. 685-694
    • Wood, L.W.1    Shillitoe, E.J.2
  • 37
    • 0029843942 scopus 로고    scopus 로고
    • The herpes simplex virus major regulatory protein ICP4 blocks apoptosis induced by the virus or by hyperthermia
    • Leopardi R, Roizman B,. The herpes simplex virus major regulatory protein ICP4 blocks apoptosis induced by the virus or by hyperthermia. Proc Natl Acad Sci USA 1996; 93: 9583-7.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9583-9587
    • Leopardi, R.1    Roizman, B.2
  • 38
    • 3042636651 scopus 로고    scopus 로고
    • Herpes simplex virus protein kinase US3 activates and functionally overlaps protein kinase A to block apoptosis
    • Benetti L, Roizman B,. Herpes simplex virus protein kinase US3 activates and functionally overlaps protein kinase A to block apoptosis. Proc Natl Acad Sci USA 2004; 101: 9411-16.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 9411-9416
    • Benetti, L.1    Roizman, B.2
  • 39
    • 0036138853 scopus 로고    scopus 로고
    • Regions of the herpes simplex virus type 1 latency-associated transcript that protect cells from apoptosis in vitro and protect neuronal cells in vivo
    • Ahmed M, Lock M, Miller CG, et al. Regions of the herpes simplex virus type 1 latency-associated transcript that protect cells from apoptosis in vitro and protect neuronal cells in vivo. J Virol 2002; 76: 717-29.
    • (2002) J Virol , vol.76 , pp. 717-729
    • Ahmed, M.1    Lock, M.2    Miller, C.G.3
  • 40
    • 64749097226 scopus 로고    scopus 로고
    • Diffuse-type gastric carcinoma: Progression, angiogenesis, and transforming growth factor beta signaling
    • Komuro A, Yashiro M, Iwata C, et al. Diffuse-type gastric carcinoma: progression, angiogenesis, and transforming growth factor beta signaling. J Natl Cancer Inst 2009; 101: 592-604.
    • (2009) J Natl Cancer Inst , vol.101 , pp. 592-604
    • Komuro, A.1    Yashiro, M.2    Iwata, C.3
  • 41
    • 0034650566 scopus 로고    scopus 로고
    • Thrombospondin-1 promotes alpha3beta1 integrin-mediated adhesion and neurite-like outgrowth and inhibits proliferation of small cell lung carcinoma cells
    • Guo N, Templeton NS, Al-Barazi H, et al. Thrombospondin-1 promotes alpha3beta1 integrin-mediated adhesion and neurite-like outgrowth and inhibits proliferation of small cell lung carcinoma cells. Cancer Res 2000; 60: 457-66.
    • (2000) Cancer Res , vol.60 , pp. 457-466
    • Guo, N.1    Templeton, N.S.2    Al-Barazi, H.3
  • 42
    • 33746542655 scopus 로고    scopus 로고
    • Txr1: A transcriptional regulator of thrombospondin-1 that modulates cellular sensitivity to taxanes
    • Lih CJ, Wei W, Cohen SN,. Txr1: a transcriptional regulator of thrombospondin-1 that modulates cellular sensitivity to taxanes. Genes Dev 2006; 20: 2082-95.
    • (2006) Genes Dev , vol.20 , pp. 2082-2095
    • Lih, C.J.1    Wei, W.2    Cohen, S.N.3
  • 43
    • 40949137307 scopus 로고    scopus 로고
    • Synergy of a herpes oncolytic virus and paclitaxel for anaplastic thyroid cancer
    • Lin SF, Gao SP, Price DL, et al. Synergy of a herpes oncolytic virus and paclitaxel for anaplastic thyroid cancer. Clin Cancer Res 2008; 14: 1519-28.
    • (2008) Clin Cancer Res , vol.14 , pp. 1519-1528
    • Lin, S.F.1    Gao, S.P.2    Price, D.L.3


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