-
1
-
-
79551487613
-
AMP-activated protein kinase: A cellular energy sensor with a key role in metabolic disorders and in cancer
-
D.G. Hardie AMP-activated protein kinase: a cellular energy sensor with a key role in metabolic disorders and in cancer Biochem. Soc. Trans. 39 2011 1 13
-
(2011)
Biochem. Soc. Trans.
, vol.39
, pp. 1-13
-
-
Hardie, D.G.1
-
2
-
-
79954517977
-
Structure of mammalian AMPK and its regulation by ADP
-
B. Xiao, M.J. Sanders, E. Underwood, R. Heath, F.V. Mayer, D. Carmena, C. Jing, P.A. Walker, J.F. Eccleston, and L.F. Haire Structure of mammalian AMPK and its regulation by ADP Nature 472 2011 230 233
-
(2011)
Nature
, vol.472
, pp. 230-233
-
-
Xiao, B.1
Sanders, M.J.2
Underwood, E.3
Heath, R.4
Mayer, F.V.5
Carmena, D.6
Jing, C.7
Walker, P.A.8
Eccleston, J.F.9
Haire, L.F.10
-
3
-
-
84863719838
-
AMP-activated protein kinase undergoes nucleotide-dependent conformational changes
-
L. Chen, J. Wang, Y.Y. Zhang, S.F. Yan, D. Neumann, U. Schlattner, Z.X. Wang, and J.W. Wu AMP-activated protein kinase undergoes nucleotide-dependent conformational changes Nat. Struct. Mol. Biol. 19 2012 716 718
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 716-718
-
-
Chen, L.1
Wang, J.2
Zhang, Y.Y.3
Yan, S.F.4
Neumann, D.5
Schlattner, U.6
Wang, Z.X.7
Wu, J.W.8
-
4
-
-
0032213768
-
AMP-activated protein kinase is activated by low glucose in cell lines derived from pancreatic beta cells, and may regulate insulin release
-
I.P. Salt, G. Johnson, S.J. Ashcroft, and D.G. Hardie AMP-activated protein kinase is activated by low glucose in cell lines derived from pancreatic beta cells, and may regulate insulin release Biochem. J. 335 1998 533 539
-
(1998)
Biochem. J.
, vol.335
, pp. 533-539
-
-
Salt, I.P.1
Johnson, G.2
Ashcroft, S.J.3
Hardie, D.G.4
-
5
-
-
0038584871
-
Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression
-
Xavier G. da Silva, I. Leclerc, A. Varadi, T. Tsuboi, S.K. Moule, and G.A. Rutter Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression Biochem. J. 371 2003 761 774
-
(2003)
Biochem. J.
, vol.371
, pp. 761-774
-
-
Da Silva, X.G.1
Leclerc, I.2
Varadi, A.3
Tsuboi, T.4
Moule, S.K.5
Rutter, G.A.6
-
6
-
-
0141905919
-
Roles of 5′-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis
-
G.A. Rutter, Xavier G. Da Silva, and I. Leclerc Roles of 5′-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis Biochem. J. 375 2003 1 16
-
(2003)
Biochem. J.
, vol.375
, pp. 1-16
-
-
Rutter, G.A.1
Da Silva, X.G.2
Leclerc, I.3
-
7
-
-
0034636006
-
Role of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression
-
Xavier G. da Silva, I. Leclerc, I.P. Salt, B. Doiron, D.G. Hardie, A. Kahn, and G.A. Rutter Role of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression Proc. Natl. Acad. Sci. USA 97 2000 4023 4028
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 4023-4028
-
-
Da Silva, X.G.1
Leclerc, I.2
Salt, I.P.3
Doiron, B.4
Hardie, D.G.5
Kahn, A.6
Rutter, G.A.7
-
8
-
-
79952114408
-
The PP1-R6 protein phosphatase holoenzyme is involved in the glucose-induced dephosphorylation and inactivation of AMP-activated protein kinase, a key regulator of insulin secretion, in MIN6 beta cells
-
L. Garcia-Haro, M.A. Garcia-Gimeno, D. Neumann, M. Beullens, M. Bollen, and P. Sanz The PP1-R6 protein phosphatase holoenzyme is involved in the glucose-induced dephosphorylation and inactivation of AMP-activated protein kinase, a key regulator of insulin secretion, in MIN6 beta cells FASEB J. 24 2010 5080 5091
-
(2010)
FASEB J.
, vol.24
, pp. 5080-5091
-
-
Garcia-Haro, L.1
Garcia-Gimeno, M.A.2
Neumann, D.3
Beullens, M.4
Bollen, M.5
Sanz, P.6
-
9
-
-
75049085233
-
PKA phosphorylates and inactivates AMPKalpha to promote efficient lipolysis
-
N. Djouder, R.D. Tuerk, M. Suter, P. Salvioni, R.F. Thali, R. Scholz, K. Vaahtomeri, Y. Auchli, H. Rechsteiner, and R.A. Brunisholz PKA phosphorylates and inactivates AMPKalpha to promote efficient lipolysis EMBO J. 29 2010 469 481
-
(2010)
EMBO J.
, vol.29
, pp. 469-481
-
-
Djouder, N.1
Tuerk, R.D.2
Suter, M.3
Salvioni, P.4
Thali, R.F.5
Scholz, R.6
Vaahtomeri, K.7
Auchli, Y.8
Rechsteiner, H.9
Brunisholz, R.A.10
-
10
-
-
33845972272
-
Regulation of AMP-activated protein kinase by multisite phosphorylation in response to agents that elevate cellular cAMP
-
R.L. Hurley, L.K. Barre, S.D. Wood, K.A. Anderson, B.E. Kemp, A.R. Means, and L.A. Witters Regulation of AMP-activated protein kinase by multisite phosphorylation in response to agents that elevate cellular cAMP J. Biol. Chem. 281 2006 36662 36672
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 36662-36672
-
-
Hurley, R.L.1
Barre, L.K.2
Wood, S.D.3
Anderson, K.A.4
Kemp, B.E.5
Means, A.R.6
Witters, L.A.7
-
11
-
-
77957124257
-
Adiponectin inhibits palmitate-induced apoptosis through suppression of reactive oxygen species in endothelial cells: Involvement of cAMP/protein kinase A and AMP-activated protein kinase
-
J.E. Kim, S.E. Song, Y.W. Kim, J.Y. Kim, S.C. Park, Y.K. Park, S.H. Baek, I.K. Lee, and S.Y. Park Adiponectin inhibits palmitate-induced apoptosis through suppression of reactive oxygen species in endothelial cells: involvement of cAMP/protein kinase A and AMP-activated protein kinase J. Endocrinol. 207 2010 35 44
-
(2010)
J. Endocrinol.
, vol.207
, pp. 35-44
-
-
Kim, J.E.1
Song, S.E.2
Kim, Y.W.3
Kim, J.Y.4
Park, S.C.5
Park, Y.K.6
Baek, S.H.7
Lee, I.K.8
Park, S.Y.9
-
12
-
-
60549083066
-
Regulation of AMP-activated protein kinase by cAMP in adipocytes: Roles for phosphodiesterases, protein kinase B, protein kinase A, Epac and lipolysis
-
B. Omar, E. Zmuda-Trzebiatowska, V. Manganiello, O. Goransson, and E. Degerman Regulation of AMP-activated protein kinase by cAMP in adipocytes: roles for phosphodiesterases, protein kinase B, protein kinase A, Epac and lipolysis Cell Signal. 21 2009 760 766
-
(2009)
Cell Signal.
, vol.21
, pp. 760-766
-
-
Omar, B.1
Zmuda-Trzebiatowska, E.2
Manganiello, V.3
Goransson, O.4
Degerman, E.5
-
13
-
-
33646828975
-
Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alpha-subunits in heart via hierarchical phosphorylation of Ser485/491
-
S. Horman, D. Vertommen, R. Heath, D. Neumann, V. Mouton, A. Woods, U. Schlattner, T. Wallimann, D. Carling, and L. Hue Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alpha-subunits in heart via hierarchical phosphorylation of Ser485/491 J. Biol. Chem. 281 2006 5335 5340
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 5335-5340
-
-
Horman, S.1
Vertommen, D.2
Heath, R.3
Neumann, D.4
Mouton, V.5
Woods, A.6
Schlattner, U.7
Wallimann, T.8
Carling, D.9
Hue, L.10
-
14
-
-
0043210478
-
Identification of phosphorylation sites in AMP-activated protein kinase (AMPK) for upstream AMPK kinases and study of their roles by site-directed mutagenesis
-
A. Woods, D. Vertommen, D. Neumann, R. Turk, J. Bayliss, U. Schlattner, T. Wallimann, D. Carling, and M.H. Rider Identification of phosphorylation sites in AMP-activated protein kinase (AMPK) for upstream AMPK kinases and study of their roles by site-directed mutagenesis J. Biol. Chem. 278 2003 28434 28442
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 28434-28442
-
-
Woods, A.1
Vertommen, D.2
Neumann, D.3
Turk, R.4
Bayliss, J.5
Schlattner, U.6
Wallimann, T.7
Carling, D.8
Rider, M.H.9
-
15
-
-
0027360242
-
Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets
-
H. Ishihara, T. Asano, K. Tsukuda, H. Katagiri, K. Inukai, M. Anai, M. Kikuchi, Y. Yazaki, J.I. Miyazaki, and Y. Oka Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets Diabetologia 36 1993 1139 1145
-
(1993)
Diabetologia
, vol.36
, pp. 1139-1145
-
-
Ishihara, H.1
Asano, T.2
Tsukuda, K.3
Katagiri, H.4
Inukai, K.5
Anai, M.6
Kikuchi, M.7
Yazaki, Y.8
Miyazaki, J.I.9
Oka, Y.10
-
16
-
-
0037382719
-
Differential activation mechanisms of Erk-1/2 and p70(S6K) by glucose in pancreatic beta-cells
-
I. Briaud, M.K. Lingohr, L.M. Dickson, C.E. Wrede, and C.J. Rhodes Differential activation mechanisms of Erk-1/2 and p70(S6K) by glucose in pancreatic beta-cells Diabetes 52 2003 974 983
-
(2003)
Diabetes
, vol.52
, pp. 974-983
-
-
Briaud, I.1
Lingohr, M.K.2
Dickson, L.M.3
Wrede, C.E.4
Rhodes, C.J.5
-
17
-
-
15044361628
-
Cooperative effects between protein kinase A and p44/p42 mitogen-activated protein kinase to promote cAMP-responsive element binding protein activation after beta cell stimulation by glucose and its alteration due to glucotoxicity
-
S. Costes, C. Longuet, C. Broca, O. Faruque, E.H. Hani, D. Bataille, and S. Dalle Cooperative effects between protein kinase A and p44/p42 mitogen-activated protein kinase to promote cAMP-responsive element binding protein activation after beta cell stimulation by glucose and its alteration due to glucotoxicity Ann. N.Y. Acad. Sci. 1030 2004 230 242
-
(2004)
Ann. N.Y. Acad. Sci.
, vol.1030
, pp. 230-242
-
-
Costes, S.1
Longuet, C.2
Broca, C.3
Faruque, O.4
Hani, E.H.5
Bataille, D.6
Dalle, S.7
-
18
-
-
0034141636
-
LKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphorylated by cAMP-dependent protein kinase (PKA) and prenylated in vivo
-
S.P. Collins, J.L. Reoma, D.M. Gamm, and M.D. Uhler LKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphorylated by cAMP-dependent protein kinase (PKA) and prenylated in vivo Biochem. J. 345 Pt. 3 2000 673 680
-
(2000)
Biochem. J.
, vol.345
, Issue.PART. 3
, pp. 673-680
-
-
Collins, S.P.1
Reoma, J.L.2
Gamm, D.M.3
Uhler, M.D.4
-
20
-
-
33846459471
-
Glucose activates a protein phosphatase-1-mediated signaling pathway to enhance overall translation in pancreatic beta-cells
-
D. Vander Mierde, D. Scheuner, R. Quintens, R. Patel, B. Song, K. Tsukamoto, M. Beullens, R.J. Kaufman, M. Bollen, and F.C. Schuit Glucose activates a protein phosphatase-1-mediated signaling pathway to enhance overall translation in pancreatic beta-cells Endocrinology 148 2007 609 617
-
(2007)
Endocrinology
, vol.148
, pp. 609-617
-
-
Vander Mierde, D.1
Scheuner, D.2
Quintens, R.3
Patel, R.4
Song, B.5
Tsukamoto, K.6
Beullens, M.7
Kaufman, R.J.8
Bollen, M.9
Schuit, F.C.10
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