The diagnostic value of D-dimer, procalcitonin and CRP in acute appendicitis

International Journal of Medical Sciences

Volumn 9, Issue 10, 2012, Pages 909-915

  Kaya, Bulent ^a   Sana, Baris ^b   Eris, Cengiz ^a   Karabulut, Koray ^c   Bat, Orhan ^d   Kutanis, Riza ^b  

^a GATA HAYDARPASA TRAINING HOSPITAL   (Turkey)

^b BAGCILAR TRAINING AND RESEARCH HOSPITAL   (Turkey)

^c FIRAT UNIVERSITY   (Turkey)

^d FSM Training and Research Hospital   (Turkey)

Author keywords

Appendicitis; C reactive protein; D dimer; Procalcitonin

Indexed keywords

C REACTIVE PROTEIN; D DIMER; PROCALCITONIN;

ABDOMINAL PAIN; ACUTE APPENDICITIS; ADULT; AGED; APPENDIX PERFORATION; ARTICLE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DISEASE CLASSIFICATION; DISEASE DURATION; DISEASE SEVERITY; FEMALE; GANGRENOUS APPENDICITIS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; NEGATIVE APPENDECTOMY; PHLEGMONOUS APPENDICITIS; PHYSICAL EXAMINATION; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; SENSITIVITY AND SPECIFICITY;

APPENDICITIS; C-REACTIVE PROTEIN.; D-DIMER; PROCALCITONIN;

ADOLESCENT; ADULT; AGED; APPENDICITIS; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CALCITONIN; FEMALE; FIBRIN FIBRINOGEN DEGRADATION PRODUCTS; HUMANS; LEUKOCYTE COUNT; MALE; MIDDLE AGED; PROTEIN PRECURSORS;

EID: 84869453259     PISSN: 14491907     EISSN: None     Source Type: Journal    
DOI: 10.7150/ijms.4733     Document Type: Article

References (33)

1. Ivancević N, Radenković D, Bumbasirević V, Karamarković A, Jeremić V, Kalezić N, Vodnik T, Beleslin B, Milić N, Gregorić P, Zarković M. Procalcitonin in preoperative diagnosis of abdominal sepsis. Langenbecks Arch Surg. 2008;393:397-403.
2. Le Moullec JM, Jullienne A, Chenais J, Lasmoles F, Guliana JM, Milhaud G, Moukhtar MS. The complete sequence of human preprocalcitonin. FEBS Lett. 1984;13:93-7.
3. Assicot M, Gendrel D, Carsin H, Raymond J, Guilbaud J, Bohuon C. High serum procalcitonin concentrations in patients with sepsis and infection. Lancet. 1993;341:515-518.
4. Maruna P, Frasko R, Gürlich R. Plasma procalcitonin in patients with ileus. Relations to other inflammatory parameters. Physiol Res. 2008;57:481-6.
5. Markogiannakis H, Memos N, Messaris E, Dardamanis D, Larentzakis A, Papanikolaou D, Zografos GC, Manouras A. Predictive value of procalcitonin for bowel ischemia and necrosis in bowel obstruction. Surgery. 2011 Mar;149(3):394-403.
6. Tillet WS, Francis T. Jr. Serological Reactions in pneumonia with a non-protein somatic fraction of pneumococcus. J Exp Med. 1930;52:561-71.
7. Eriksson S, Granstrom L. Laboratory tests in patients with suspected acute appendicitis. Acta Chir Scand. 1994;155:117-2.
8. Shakhatreh HS. The accuracy of C-reactive protein in the diagnosis of acute appendicitis compared with that of clinical diagnosis. Med Arh. 2000;54:109-10.
9. Colson M, Skinner KA, Dunnignton G. High negative appendectomy rates are no longer acceptable. Am J Surg 1997;174: 723-6.
10. Espinoza R, Ohmke J, García-Huidobro I, Guzmán S, Azocar M. Negative appendectomy: experience at a universty hospital. Rev Med Chil 1998; 126: 75-80.
11. Fingerhut A, Yahchouchy-Chouillard E, Etrenne JC. Appendicitis or nonspesific pain in the right iliac fossa. Rev Prot 2001; 51: 1654-6.
12. Agrawal CS, Adhikari S, Kumar M. Role of serum C-reactive protein and leukocyte count in the diagnosis of acute appendicitis in Nepalese population. Nepal Med Coll J. 2008; 10:11-5.
13. Grönroos JM, Forsström JJ, Irjala K, Nevalainen TJ. Phospholipase A2, C-reactive protein, and white blood cell count in the diagnosis of acute appendicitis. Clin Chem 1994;40:1757-60.
14. Lycopoulou L, Mamoulakis C, Hantzi E, Demetriadis D, Antypas S, Giannaki M, Bakoula C, Chrousos G, Papassotiriou I. Serum amyloid A protein levels as a possible aid in the diagnosis of acute appendicitis in children. Clin Chem Lab Med 2005;43:49-53.
15. Dalal I, Somekh E, Bilker-Reich A, Boaz M, Gorenstein A, Serour F. Serum and peritoneal inflammatory mediators in children with suspected acute appendicitis. Arch Surg 2005;140:169-73.
16. Hatherill M, Jones G, Lim E, Tibby SM, Murdoch IA. Procalcitonin aids diagnosis of adrenocortical failure. Lancet 1997;350:1749-50.
17. Sand M, Trullen XV, Bechara FG, Pala XF, Sand D, Landgrafe G, Mann B. A prospective bicenter study investigating the diagnostic value of procalcitonin in patients with acute appendicitis. Eur Surg Res. 2009;43:291-7.
18. Kouame DB, Garrigue MA, Lardy H, Machet MC, Giraudeau B, Robert M. Is procalcitonin able to help in pediatric appendicitis diagnosis? Ann Chir. 2005; 130:169-74.
19. Aslan A, Karaveli C, Ogunc D, Elpek O, Karaguzel G, Melikoglu M. Does noncomplicated acute appendicitis cause bacterial translocation? Pediatr Surg Int 2007; 23: 555-558.
20. Harrison KA, Haire WD, Pappas AA, Purnell GL, Palmer S, Holdeman KP, Fink LM, Dalrymple GV. Plasma D-Dimer: a useful tool for evaluating suspected pulmonary embolus. J Nucl Med 1993;34:896-8.
21. Meissner MH, Zierler BK, Bergelin RO, Chandler WC, Manzo RA, Strandness DE Jr. Markers of plasma coagulation and fibrinolysis after acute deep venous thrombosis. J Vasc Surg 2000;32:870-80.
22. Bayes-Genis A, Mateo J, Santaló M, Oliver A, Guindo J, Badimon L. D-Dimer is an early diagnostic marker of coronary ischemia in patients with chest pain. Am Heart J 2000;140:379-84.
23. Engelman DT, Gabram SG, Allen L, Ens GE, Jacobs LM. Hypercoagulability following multiple trauma. World J Surg 1996;20:5-10.
24. Raimondi P, Bongard O, de Moerloose P, Reber G, Waldvogel F, Bounameaux H. D-dimer plasma concentration in various clinical conditions: Implication for the use of this test in the diagnostic approach of venous thromboembolism. Thromb Res 1993;69:125-30.
25. Kurt Y, Akin ML, Demirbas S, Uluutku AH, Gulderen M, Avsar K, Celenk T. D-dimer in the early diagnosis of acute mesenteric ischemia secondary to arterial occlusion in rats. Eur Surg Res. 2005; 37: 216-9.
26. Akyildiz HY, Sözüer E, Akcan A, Küçük C, Artis T, Biri I, Yilmaz N. The value of D-dimer test in the diagnosis of patients with nontraumatic acute abdomen. Ulus Travma Acil Cerrahi Derg. 2010; 16:22-6.
27. Mentes O, Eryilmaz M, Harlak A, Ozer T, Balkan M, Kozak O, Tufan T. D-dimer become a new diagnostic parameter for acute appendicitis? Am J Emerg Med.2009; 27:765-9.
28. al-Saigh AH. C-reactive protein in the differential diagnosis of the acute abdomen, especially acute appendicitis. J R Coll Surg Edinb 1992; 37:238-40.
29. Gurleyik E, Gurleyik G, Unalmiser S. Accuracy of serum C-reactive protein measurements in diagnosis of acute appendicitis compared with surgeon's clinical impression. Dis Colon Rectum 1995; 38: 1270-4.
30. Yang HR, Wang YC, Chung PK, Chen WK, Jeng LB, Chen RJ. Role of leukocyte count, neutrophil percentage, and C-reactive protein in the diagnosis of acute appendicitis in the elderly. Am Surg 2005; 71: 344-7.
31. Hallan S. Asberg A. The accuracy of C-reactive protein in diagnosing acute appendicitis-a meta-analysis. Scand J Clin Lab Invest 1997; 57: 373-80.
32. Grönroos JM, Grönroos P. Leucocyte count and C-reactive protein in the diagnosis of acute appendicitis. Br J Surg 1999;86:501-4.
33. Ortega-Deballon P, Ruiz de Adana-Belbel JC, Hernández-Matías A, García-Septiem J, Moreno-Azcoita M. Usefulness of laboratory data in the management of right iliac fossa pain in adults. Dis Colon Rectum. 2008; 51:1093-9.