DISC1 as a therapeutic target for mental illnesses

Expert Opinion on Therapeutic Targets

Volumn 16, Issue 12, 2012, Pages 1151-1160

  Hikida, Takatoshi ^a,b,c   Gamo, Nao J ^d   Sawa, Akira ^d  

^a KYOTO UNIVERSITY   (Japan)

^b OSAKA BIOSCIENCE INSTITUTE   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Autism; Bipolar disorder; Depression; DISC1; Interactome; Mental illnesses; Mouse models; Psychiatric diseases; Schizophrenia

Indexed keywords

2,2' DIHYDROXY 1,1' DINAPHTHYLDISULFIDE; 4 AMINO 6 [2 [[4 (DIETHYLAMINO) 1 METHYLBUTYL]AMINO] 6 METHYL 4 PYRIMIDINYL] 2 METHYLQUINOLINE; ACTIVATING TRANSCRIPTION FACTOR 4; CILOMILAST; CP 668863; CP 681301; CYCLIN DEPENDENT KINASE INHIBITOR; DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; GUANINE NUCLEOTIDE EXCHANGE FACTOR; IPA 3; KALIRIN 7; LITHIUM; NCK INTERACTING KINASE; NUCLEAR PROTEIN; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE IV INHIBITOR; PROTEIN INHIBITOR; PROTEIN NUDE LIKE 1; PROTEIN SERINE THREONINE KINASE; ROFLUMILAST; ROLIPRAM; TIDEGLUSIB; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; BEHAVIOR CHANGE; BINDING SITE; BIPOLAR DISORDER; BLOOD BRAIN BARRIER; CHRONIC OBSTRUCTIVE LUNG DISEASE; COGNITION; DEPRESSION; DISEASE MODEL; DISRUPTED IN SCHIZOPHRENIA 1 GENE; DRUG TARGETING; GENE; GENETIC TRANSCRIPTION; HISTOPATHOLOGY; HUMAN; MENTAL DISEASE; NAUSEA AND VOMITING; NONHUMAN; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN TARGETING; RESPIRATORY TRACT INFLAMMATION; REVIEW; SCHIZOPHRENIA; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION;

ANIMALS; HUMANS; MENTAL DISORDERS; NERVE TISSUE PROTEINS;

EID: 84869439022     PISSN: 14728222     EISSN: 17447631     Source Type: Journal    
DOI: 10.1517/14728222.2012.719879     Document Type: Review

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