Antiviral escape strategies developed by bunyaviruses pathogenic for humans

Frontiers in Bioscience - Scholar

Volumn 4 S, Issue 3, 2012, Pages 1065-1077

  Le May, Nicolas ^a   Bouloy, Michele ^b  

^a CNRS   (France)

^b INSTITUT PASTEUR   (France)

Author keywords

Bunyaviruses; Escape; Innate immunity; Virulence factors

Indexed keywords

ALPHA1 INTERFERON; ANTIVIRUS AGENT; BETA INTERFERON; DAXX PROTEIN; GLYCOPROTEIN; GLYCOPROTEIN GC; GLYCOPROTEIN GN; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INITIATION FACTOR 2ALPHA; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 7; INTERFERON REGULATORY FACTOR 9; JANUS KINASE; LIVE VACCINE; MESSENGER RNA; PATTERN RECOGNITION RECEPTOR; PROTEIN KINASE TYK2; PROTEIN P53; RETINOIC ACID INDUCIBLE PROTEIN I; RIBOSOME PROTEIN; STAT1 PROTEIN; STAT2 PROTEIN; SUMO 1 PROTEIN; UBIQUITIN CONJUGATING ENZYME; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS RNA;

ANTIVIRAL ACTIVITY; ARTICLE; BUNYAMWERA VIRUS; BUNYAVIRUS; CELL FUNCTION; COMPLEX FORMATION; CRIMEAN CONGO HEMORRHAGIC FEVER; CYTOKINE RELEASE; DOWN REGULATION; HANTAVIRUS; HUMAN; INNATE IMMUNITY; INTRACELLULAR SIGNALING; LA CROSSE VIRUS; MORTALITY; NAIRO VIRUS; NONHUMAN; ORTHOBUNYAVIRUS; PHLEBOVIRUS; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RIFT VALLEY FEVER; RIFT VALLEY FEVER BUNYAVIRUS; RNA SYNTHESIS; TRANSLATION INITIATION; VIRUS INHIBITION; VIRUS NUCLEOCAPSID; VIRUS REPLICATION; VIRUS VIRULENCE; ANIMAL; BUNYAVIRUS INFECTION; IMMUNOLOGY; PATHOGENICITY; PHYSIOLOGY; REVIEW; VIROLOGY; VIRULENCE;

ARBOVIRUS; BUNYAVIRIDAE; HANTAVIRUS; NAIROVIRUS; ORTHOBUNYAVIRUS; PHLEBOVIRUS; RNA VIRUSES; TOSPOVIRUS;

ANIMALS; BUNYAVIRIDAE; BUNYAVIRIDAE INFECTIONS; HUMANS; IMMUNITY, INNATE; VIRULENCE;

EID: 84869419894     PISSN: 19450516     EISSN: 19450524     Source Type: Journal    
DOI: None     Document Type: Article

References (80)

1. Kat. Jones, Nikkit. Patel, Mar. Levy, Ada. Storeygard, Debora. Balk, John Gittleman and Peter Daszak: Global trends in emerging infectious diseases. Nature, 451(7181), 990-3 (2008) (Pubitemid 351301726)
2. Richard Elliott: Bunyaviruses and climate change. Clin Microbiol Infect, 15(6), 510-7 (2009)
3. Ernie Gould and Stephen Higgs: Impact of climate change and other factors on emerging arbovirus diseases. Trans R Soc Trop Med Hyg, 103(2), 109-21 (2009)
4. Yong-Zhe. Zhang, Dun-Ji. Zhou, Yanwe. Xiong, Xiao. Ping Chen, Yong-We. He, Qiangzhen. Sun, Bi. Yu, J. Li, Yong-A. Dai, Jun-Hu. Tian, Xin-Chen. Qin, Don. Jin, Zhigan. Cui, Xue-Lia. Luo, We. Li, Sha. Lu, We. Wang, Jin-Son. Peng, Wen-Pin. Guo, Ming-hu. Li, Zhen-Ju. Li, Shaomi. Zhang, Che. Chen, Ya. Wang, Menno de Jong and Jianguo Xu: [Hemorrhagic fever caused by a novel tick-borne Bunyavirus in Huaiyangshan, China.]. Zhonghua Liu Xing Bing Xue Za Zhi, 32(3), 209-220 (2011)
5. Xue-Ji. Yu, Mi-Fan. Liang, Shou-Yi. Zhang, Ya. Liu, Jian-Don. Li, Yu-La. Sun, Lihon. Zhang, Quan-F. Zhang, Vsevolo. Popov, Chua. Li, Jin. Qu, Qu. Li, Yan. Ping Zhang, Ron. Hai, We. Wu, Qi. Wang, Fa-Xia. Zhan, Xian-Ju. Wang, Bia. Kan, Shi-We. Wang, Kang-L. Wan, Huai-Q. Jing, Jin-Xi. Lu, Wen-W. Yin, Han. Zhou, Xu. Hua Guan, Jia-F. Liu, Zhen-Qian. Bi, Guo-Hu. Liu, Ju. Ren, Hu. Wang, Zhu. Zhao, Jing-Don. Song, Jin-Ron. He, Ta. Wan, Jin-Shan. Zhang, Xiao-Pin. Fu, Li-N. Sun, Xiu-Pin. Dong, Zi-Jia. Feng, Wei-Zhon. Yang, Ta. Hong, Y. Zhang, Davi. Walker, Yu Wang and De-Xin Li: Fever with thrombocytopenia associated with a novel bunyavirus in China. N Engl J Med, 364(16), 1523-32 (2011)
6. Richar. Elliott, Michèl. Bouloy, Charle. Calisher, Ro. Goldbach, Jac. Moyer, Stuar. Nichol, Ral. Pettersson, Alexander Plyusnin and Connie Schmaljohn: Family Bunyaviridae. In: Virus taxonomy. classification and nomenclature of viruses. Seventh report of the intenational committee on taxonomy of viruses. Ed M. H. V. Van Regenmortel, C. M. Fauquet, D. H. L. Bishop, E. B. Cartens, M. K. Estes, L. S. M., J. Maniloff, M. A. Mayo, D. J. McGeoch, P. C. R. & W. R. B. academic press, San Diego (2000)
7. Mohammed Mir: Hantaviruses. Clin Lab Med, 30(1), 67-91 (2010)
8. Sonia Gerrard and Stuart Nichol: Characterization of the Golgi retention motif of Rift Valley fever virus G (N) glycoprotein. Journal of Virology, 76(23), 12200-10 (2002) (Pubitemid 35304317)
9. Xiaohon. Shi, Joe. van Mierlo, Andrew French and Richard Elliott: Visualizing the replication cycle of bunyamwera orthobunyavirus expressing fluorescent protein-tagged Gc glycoprotein. J Virol, 84(17), 8460-9 (2010)
10. Jua. Reguera, Friedemann Weber and Stephen Cusack: Bunyaviridae RNA polymerases (L-protein) have an Nterminal, influenza-like endonuclease domain, essential for viral cap-dependent transcription. PLoS Pathog, 6 (9) (2010)
11. Shuenn-Ju. Wu, Geraldin. Grouard-Vogel, Wellingto. Sun, Joh. Mascola, Elen. Brachtel, Ravitah. Putvatana, Mar. Louder, Lui. Filgueira, Mar. Marovich, Henr. Wong, Andre. Blauvelt, Geral. Murphy, Merli. Robb, Bruc. Innes, Debora. Birx, Curtis Hayes and Sarah Frankel: Human skin Langerhans cells are targets of dengue virus infection. Nat Med, 6(7), 816-20 (2000) (Pubitemid 30469433)
12. Kristin Rogers and Mark Heise: Modulation of cellular tropism and innate antiviral response by viral glycans. J Innate Immun, 1(5), 405-12 (2009)
13. Alick Isaacs and Jean Lindenmann: Virus interference. I. The interferon. Proc R Soc Lond B Biol Sci, 147(927), 258-67 (1957)
14. Alic. Isaacs, Jean Lindenmann and Roger Valentine: Virus interference. II. Some properties of interferon. Proc R Soc Lond B Biol Sci, 147(927), 268-73 (1957)
15. Katherin. Fitzgerald, Sara. McWhirter, Kerri. Faia, Danie. Rowe, Eick. Latz, Dougla. Golenbock, Anthon. Coyle, Sha-Mei Liao and Tom Maniatis: IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. Nat Immunol, 4(5), 491-6 (2003) (Pubitemid 36592443)
16. Mayr. Solis, Delphin. Goubau, Raphaell. Romieu-Mourez, Pierr. Genin, Ahmet Civas and John Hiscott: Distinct functions of IRF-3 and IRF-7 in IFN-alpha gene regulation and control of anti-tumor activity in primary macrophages. Biochem Pharmacol, 72(11), 1469-76 (2006) (Pubitemid 44666732)
17. Leonidas Platanias: Mechanisms of type-I-and type-IIinterferonmediated signalling. Nat Rev Immunol, 5(5), 375-86 (2005)
18. Christia. Schindler, David Levy and Thomas Decker: JAK-STAT signaling: from interferons to cytokines. J Biol Chem, 282(28), 20059-63 (2007) (Pubitemid 47099977)
19. Sand. Der, Aimi. Zhou, Bryan Williams and Robert Silverman: Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays. Proc Natl Acad Sci U S A, 95(26), 15623-8 (1998) (Pubitemid 29018750)
20. Ganes Sen and Gregory Peters: Viral stress-inducible genes. Adv Virus Res, 70, 233-63 (2007)
21. Gjo. Blakqori, Sophi. Delhaye, Matthia. Habjan, Caro. Blair, Irm. Sanchez-Vargas, Ke. Olson, Ghasse. Attarzadeh-Yazdi, Renno. Fragkoudis, Alai. Kohl, Ulric. Kalinke, Siegfrie. Weiss, Thoma. Michiels, Peter Staeheli and Friedemann Weber: La Crosse bunyavirus nonstructural protein NSs serves to suppress the type I interferon system of mammalian hosts. J Virol, 81(10), 4991-9 (2007) (Pubitemid 46744411)
22. Friedeman. Weber, Ann. Bridgen, Joh. Fazakerley, Hei. Streitenfeld, Nin. Kessler, Richard Randall and Richard Elliott: Bunyamwera bunyavirus nonstructural protein NSs counteracts the induction of alpha/beta interferon. J Virol, 76(16), 7949-55 (2002) (Pubitemid 34809048)
23. Ann. Bridgen, Friedeman. Weber, John Fazakerley and Richard Elliott: Bunyamwera bunyavirus nonstructural protein NSs is a nonessential gene product that contributes to viral pathogenesis. Proc Natl Acad Sci U S A, 98(2), 664-9 (2001) (Pubitemid 32105100)
24. Hei. Streitenfeld, Amand. Boyd, Joh. Fazakerley, Ann. Bridgen, Richard Elliott and Friedemann Weber: Activation of PKR by Bunyamwera virus is independent of the viral interferon antagonist NSs. J Virol, 77(9), 5507-11 (2003) (Pubitemid 36460965)
25. Alai. Kohl, Reginal. Clayton, Friedeman. Weber, Ann. Bridgen, Richard Randall and Richard Elliott: Bunyamwera virus nonstructural protein NSs counteracts interferon regulatory factor 3-mediated induction of early cell death. J Virol, 77(14), 7999-8008 (2003) (Pubitemid 36792796)
26. Danie. Thomas, Gjo. Blakqori, Valentin. Wagner, Mariu. Banholzer, Nin. Kessler, Richar. Elliott, Otto Haller and Friedemann Weber: Inhibition of RNA polymerase II phosphorylation by a viral interferon antagonist. J Biol Chem, 279(30), 31471-7 (2004) (Pubitemid 39037815)
27. Vincen. Leonard, Alai. Kohl, Thimothy Hart and Richard Elliott: Interaction of Bunyamwera Orthobunyavirus NSs protein with mediator protein MED8: a mechanism for inhibiting the interferon response. J Virol, 80(19), 9667-75 (2006) (Pubitemid 44435641)
28. Amelia Casamassimi and Claudio Napoli: Mediator complexes and eukaryotic transcription regulation: an overview. Biochimie, 89(12), 1439-46 (2007) (Pubitemid 350122855)
29. Zhiyua. Yang, Jaspe. Yik, Ruicha. Chen, Nanha. He, Moo. Kyoo Jang, Keiko Ozato and Qiang Zhou: Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4. Mol Cell, 19(4), 535-45 (2005) (Pubitemid 41140010)
30. Ingebor. van Knippenberg, Charlie Carlton-Smith and Richard Elliott: The N-terminus of Bunyamwera orthobunyavirus NSs protein is essential for interferon antagonism. J Gen Virol, 91(Pt 8), 2002-6 (2010)
31. Matthia. Habjan, Andrea. Pichlmair, Richar. Elliott, Ann. Overby, Tim. Glatter, Matthia. Gstaiger, Giuli. Superti-Furga, Hermann Unger and Friedemann Weber: NSs protein of rift valley fever virus induces the specific degradation of the double-stranded RNA-dependent protein kinase. J Virol, 83(9), 4365-75 (2009)
32. Pau. Verbruggen, Mariu. Ruf, Gjo. Blakqori, Ann. Overby, Marti. Heidemann, Dirk Eick and Friedemann Weber: Interferon antagonist NSs of La Crosse virus triggers a DNA damage response-like degradation of transcribing RNA polymerase II. J Biol Chem, 286(5), 3681-92 (2011)
33. Gjon Blakqori and Friedemann Weber: Efficient cDNAbased rescue of La Crosse bunyaviruses expressing or lacking the nonstructural protein NSs. J Virol, 79(16), 10420-8 (2005) (Pubitemid 41098582)
34. Danie. Colon-Ramos, Pabl. Irusta, Eugen. Gan, Michae. Olson, Jaewha. Song, Richar. Morimoto, Richar. Elliott, Mar. Lombard, Rober. Hollingsworth, J Mari. Hardwick, Gary Smith and Sally Kornbluth: Inhibition of translation and induction of apoptosis by Bunyaviral nonstructural proteins bearing sequence similarity to reaper. Mol Biol Cell, 14(10), 4162-72 (2003) (Pubitemid 37186317)
35. Samanth. Soldan, Matthe. Plassmeyer, Meghan Matukonis and Francisco Gonzalez-Scarano: La Crosse virus nonstructural protein NSs counteracts the effects of short interfering RNA. J Virol, 79(1), 234-44 (2005) (Pubitemid 39648379)
36. Jessic. Levine, Josep. Prescott, Kyl. Brown, Sonj. Best, Hideki Ebihara and Heinz Feldmann: Antagonism of type I interferon responses by new world hantaviruses. J Virol, 84(22), 11790-801 (2010)
37. Valer. Matthys, Elen. Gorbunova, Irin. Gavrilovskaya, Timothy Pepini and Erich Mackow: The C-terminal 42residues of the tula virus gn protein regulate interferon induction. J Virol, 85(10), 4752-60 (2011)
38. Pete. Alff, Irin. Gavrilovskaya, Elen. Gorbunova, Kare. Endriss, Yuso. Chong, Erik. Geimonen, Nandin. Sen, Nancy Reich and Erich Mackow: The pathogenic NY-1 hantavirus G1 cytoplasmic tail inhibits RIG-I-and TBK-1-directed interferon responses. J Virol, 80(19), 9676-86 (2006) (Pubitemid 44435642)
39. Pete. Alff, Nandin. Sen, Elen. Gorbunova, Irina Gavrilovskaya and Erich Mackow: The NY-1 hantavirus Gn cytoplasmic tail coprecipitates TRAF3 and inhibits cellular interferon responses by disrupting TBK1-TRAF3 complex formation. J Virol, 82(18), 9115-22 (2008)
40. Joel Pomerantz and David Baltimore: NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase. EMBO J, 18(23), 6694-704 (1999)
41. Gagi. Oganesyan, Supriy. Saha, Beich. Guo, Jeanni. He, Aras. Shahangian, Bria. Zarnegar, Andrea Perry and Genhong Cheng: Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response. Nature, 439(7073), 208-11 (2006) (Pubitemid 43083142)
42. Christin. Spiropoulou, Cesa. Albarino, Thomas Ksiazek and Pierre Rollin: Andes and Prospect Hill hantaviruses differ in early induction of interferon although both can downregulate interferon signaling. J Virol, 81(6), 2769-76 (2007) (Pubitemid 46447041)
43. Mohammed Mir and Antonito Panganiban: Trimeric hantavirus nucleocapsid protein binds specifically to the viral RNA panhandle. J Virol, 78(15), 8281-8 (2004) (Pubitemid 38944312)
44. Mohammed Mir and Antonito Panganiban: The hantavirus nucleocapsid protein recognizes specific features of the viral RNA panhandle and is altered in conformation upon RNA binding. J Virol, 79(3), 1824-35 (2005) (Pubitemid 40459127)
45. Erdon. Cheng, Absaru. Haque, Mar. Ashley Rimmer, Isla. Hussein, Sheem. Sheema, Alex Little and Mohammed Mir: Characterization of the Interaction between Hantavirus Nucleocapsid Protein (N) and Ribosomal Protein S19 (RPS19). J Biol Chem, 286(13), 11814-24 (2011)
46. Byoung-He. Lee, Kumik. Yoshimatsu, Aakihik. Maeda, Kazuhik. Ochiai, Masam. Morimatsu, Koich. Araki, Michik. Ogino, Shigeru Morikawa and Jiro Arikawa: Association of the nucleocapsid protein of the Seoul and Hantaan hantaviruses with small ubiquitin-like modifier-1-related molecules. Virus Res, 98(1), 83-91 (2003) (Pubitemid 37377930)
47. Pas. Kaukinen, Antti Vaheri and Alexander Plyusnin: Non-covalent interaction between nucleocapsid protein of Tula hantavirus and small ubiquitin-related modifier-1, SUMO-1. Virus Res, 92(1), 37-45 (2003) (Pubitemid 36246654)
48. Xiao-Don. Li, Tom. Makela, Deyi. Guo, Raba. Soliymani, Ves. Koistinen, Oll. Vapalahti, Antti Vaheri and Hilkka Lankinen: Hantavirus nucleocapsid protein interacts with the Fas-mediated apoptosis enhancer Daxx. J Gen Virol, 83(Pt 4), 759-66 (2002) (Pubitemid 34284859)
49. Shanno. Taylor, Natali. Frias-Staheli, Adolfo Garcia-Sastre and Connie Schmaljohn: Hantaan virus nucleocapsid protein binds to importin alpha proteins and inhibits tumor necrosis factor alpha-induced activation of nuclear factor kappa B. J Virol, 83(3), 1271-9 (2009)
50. Shanno. Taylor, Ryan Krempel and Connie Schmaljohn: Inhibition of TNF-alpha-induced activation of NF-kappaB by hantavirus nucleocapsid proteins. Ann N Y Acad Sci, 1171 Suppl 1, E86-93 (2009)
51. Alexander Plyusnin: Genetics of hantaviruses: implications to taxonomy. Arch Virol, 147(4), 665-82 (2002) (Pubitemid 34294278)
52. Kirs. Jaaskelainen, Angelin. Plyusnina, Aak. Lundkvist, Antti Vaheri and Alexander Plyusnin: Tula hantavirus isolate with the full-length ORF for nonstructural protein NSs survives for more consequent passages in interferon-competent cells than the isolate having truncated NSs ORF. Virol J, 5, 3 (2008)
53. Juss. Virtanen, Kirs. Jaaskelainen, J. Djupsjobacka, Antti Vaheri and Alexander Plyusnin: Tula hantavirus NSs protein accumulates in the perinuclear area in infected and transfected cells. Arch Virol, 155(1), 117-21 (2010)
54. Kirs. Jaaskelainen, Pas. Kaukinen, Ekaterin. Minskaya, Angelin. Plyusnina, Oll. Vapalahti, Richar. Elliott, Friedeman. Weber, Antti Vaheri and Alexander Plyusnin: Tula and Puumala hantavirus NSs ORFs are functional and the products inhibit activation of the interferon-beta promoter. J Med Virol, 79(10), 1527-36 (2007) (Pubitemid 47328742)
55. Alexander Plyusnin and Sergey Morzunov: Virus evolution and genetic diversity of hantaviruses and their rodent hosts. Curr Top Microbiol Immunol, 256, 47-75 (2001) (Pubitemid 32016373)
56. Friedemann Weber and Ali Mirazimi: Interferon and cytokine responses to Crimean Congo hemorrhagic fever virus; an emerging and neglected viral zonoosis. Cytokine Growth Factor Rev, 19(5-6), 395-404 (2008)
57. Sando. Bereczky, Gunne. Lindegren, Hele. Karlberg, Sar. Akerstrom, Jonas Klingstrom and Ali Mirazimi: Crimean-Congo hemorrhagic fever virus infection is lethal for adult type I interferon receptor-knockout mice. J Gen Virol, 91(Pt 6), 1473-7 (2010)
58. Denni. Bente, Judi. Alimonti, Wun-J. Shieh, Gaell. Camus, Ut. Stroher, Sherif Zaki and Steven Jones: Pathogenesis and immune response of Crimean-Congo hemorrhagic fever virus in a STAT-1 knockout mouse model. J Virol, 84(21), 11089-100 (2010)
59. Id. Andersson, Lind. Bladh, Mehrda. Mousavi-Jazi, Karl-Eri. Magnusson, Ak. Lundkvist, Otto Haller and Ali Mirazimi: Human MxA protein inhibits the replication of Crimean-Congo hemorrhagic fever virus. J Virol, 78(8), 4323-9 (2004) (Pubitemid 38437235)
60. Id. Andersson, Ak. Lundkvist, Otto Haller and Ali Mirazimi: Type I interferon inhibits Crimean-Congo hemorrhagic fever virus in human target cells. J Med Virol, 78(2), 216-22 (2006) (Pubitemid 43132566)
61. Matthia. Habjan, Id. Andersson, Jona. Klingstrom, Michae. Schumann, Aarnol. Martin, Petr. Zimmermann, Valentin. Wagner, Andrea. Pichlmair, Ur. Schneider, Elk. Muhlberger, Ali Mirazimi and Friedemann Weber: Processing of genome 5' termini as a strategy of negativestrand RNA viruses to avoid RIG-I-dependent interferon induction. PLoS One, 3(4), e2032 (2008)
62. Id. Andersson, Hele. Karlberg, Mehrda. Mousavi-Jazi, Lui. Martinez-Sobrido, Friedemann Weber and Ali Mirazimi: Crimean-Congo hemorrhagic fever virus delays activation of the innate immune response. J Med Virol, 80(8), 1397-404 (2008) (Pubitemid 351897412)
63. Natali. Frias-Staheli, Nadi. Giannakopoulos, Marjolei. Kikkert, Shanno. Taylor, Ann. Bridgen, Jaso. Paragas, Juerge. Richt, Raymon. Rowland, Conni. Schmaljohn, Debora. Lenschow, Eri. Snijder, Adolfo Garcia-Sastre and Herbert Virgin: Ovarian tumor domain-containing viral proteases evade ubiquitin-and ISG15-dependent innate immune responses. Cell Host Microbe, 2(6), 404-16 (2007) (Pubitemid 350225347)
64. Eri. Bergeron, Cesa. Albarino, Marina Khristova and Stuart Nichol: Crimean-Congo hemorrhagic fever virusencoded ovarian tumor protease activity is dispensable for virus RNA polymerase function. J Virol, 84(1), 216-26 (2010)
65. Colomb. Giorgi, Luis. Accardi, Loredan. Nicoletti, Mari. Cristina Gro, Kazuhik. Takehara, C Hilditch, Saeko Morikawa and David Bishop: Sequences and coding strategies of the S RNAs of Toscana and Rift Valley fever viruses compared to those of Punta Toro, Sicilian Sandfly fever, and Uukuniemi viruses. Virology, 180(2), 738-53 (1991)
66. Ramon Flick and Michèle Bouloy: Rift Valley fever virus. Curr Mol Med, 5(8), 827-34 (2005) (Pubitemid 43009521)
67. Agnè. Billecocq, Marti. Spiegel, Pierr. Vialat, Alai. Kohl, Friedeman. Weber, Michèle Bouloy and Otto Haller: NSs protein of Rift Valley fever virus blocks interferon production by inhibiting host gene transcription. J Virol, 78(18), 9798-806 (2004) (Pubitemid 39187098)
68. Michèl. Bouloy, Christia. Janzen, Pierr. Vialat, Huo. Khun, Jova. Pavlovic, Michel Huerre and Otto Haller: Genetic evidence for an interferon-antagonistic function of rift valley fever virus nonstructural protein NSs. J Virol, 75(3), 1371-7 (2001) (Pubitemid 32094695)
69. Nicola. Le May, Zeyn. Mansuroglu, Psylvi. Leger, Thibau. Josse, Guillaum. Blot, Agnè. Billecocq, Ramo. Flick, Yve. Jacob, Eliette Bonnefoy and Michèle Bouloy: A SAP30 complex inhibits IFN-beta expression in Rift Valley fever virus infected cells. PLoS Pathog, 4(1), e13 (2008)
70. Alexande. Zhovmer, Valentin Oksenych and Frederic Coin: Two sides of the same coin: TFIIH complexes in transcription and DNA repair. ScientificWorldJournal, 10, 633-43 (2010)
71. Birt. Kalveram, Olga Lihoradova and Tetsuro Ikegami: NSs Protein of Rift Valley Fever Virus Promotes Post-Translational Downregulation of the TFIIH Subunit p62. J Virol (2011)
72. Nicola. Le May, Sand. Dubaele, Luc. Proietti De Santis, Agnè. Billecocq, Michèle Bouloy and Jean-Marc Egly: TFIIH transcription factor, a target for the Rift Valley hemorrhagic fever virus. Cell, 116(4), 541-50 (2004) (Pubitemid 38264431)
73. Tetsur. Ikegami, Krishn. Narayanan, Sungyon. Won, Watar. Kamitani, C. J. Peters and Shinji Makino: Rift Valley fever virus NSs protein promotes posttranscriptional downregulation of protein kinase PKR and inhibits eIF2alpha phosphorylation. PLoS Pathog, 5(2), e1000287 (2009)
74. Zeyn. Mansuroglu, Tibaut. Josse, Jerom. Gilleron, Agnè. Billecocq, Psylvi. Leger, Michèle Bouloy and Eliette Bonnefoy: Nonstructural NSs protein of rift valley fever virus interacts with pericentromeric DNA sequences of the host cell, inducing chromosome cohesion and segregation defects. J Virol, 84(2), 928-39 (2010)
75. Luc. Perrone, Krishn. Narayanan, Melissa Worthy and C. J. Peters: The S segment of Punta Toro virus (Bunyaviridae, Phlebovirus) is a major determinant of lethality in the Syrian hamster and codes for a type I interferon antagonist. J Virol, 81(2), 884-92 (2007) (Pubitemid 46067913)
76. Giann. Gori Savellini, Friedeman. Weber, Chiar. Terrosi, Matthia. Habjan, Barbara Martorelli and Maria Grazia Cusi: Toscana virus induces interferon although its NSs protein reveals antagonistic activity. J Gen Virol, 92(Pt 1), 71-9 (2011)
77. Taissi. Popova, Michae. Turell, Virgini. Espina, Kylen. Kehn-Hall, Jessic. Kidd, Aarth. Narayanan, Lanc. Liotta, Emmanue. Petricoin, 3rd. Fata Kashanchi, Charles Bailey and Serguei Popov: Reverse-phase phosphoproteome analysis of signaling pathways induced by Rift valley fever virus in human small airway epithelial cells. PLoS One, 5(11), e13805 (2010)
78. Sungyon. Won, Tetsur. Ikegami, C. J. Peters and Shinji Makino: NSm protein of Rift Valley fever virus suppresses virus-induced apoptosis. J Virol, 81(24), 13335-45 (2007) (Pubitemid 350247830)
79. Baptist. Dungu, Ia. Louw, Aliso. Lubisi, Pamel. Hunter, Beate von Teichman and Michèle Bouloy: Evaluation of the efficacy and safety of the Rift Valley Fever Clone 13 vaccine in sheep. Vaccine, 28(29), 4581-7 (2010)
80. Tetsur. Ikegami, Sungyon. Won, C. J. Peters and Shinji Makino: Rescue of infectious rift valley fever virus entirely from cDNA, analysis of virus lacking the NSs gene, and expression of a foreign gene. J Virol, 80(6), 2933-40 (2006) (Pubitemid 43346388)