Processive proteolysis by γ-secretase and the mechanism of Alzheimer's disease

Biological Chemistry

Volumn 393, Issue 9, 2012, Pages 899-905

  Wolfe, Michael S ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Amyloid; Carboxypeptidase; Endoproteolysis; Presenilin; Protease

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; CARBOXYPEPTIDASE; GAMMA SECRETASE; NICASTRIN; PRESENILIN 1; PRESENILIN 2;

ALZHEIMER DISEASE; AMINO TERMINAL SEQUENCE; CARBOXY TERMINAL SEQUENCE; CONFERENCE PAPER; ENZYME ACTIVITY; EXON; GAIN OF FUNCTION MUTATION; GENE DELETION; HUMAN; LOSS OF FUNCTION MUTATION; NEUROPATHOLOGY; NEUROTOXICITY; NONHUMAN; NONSENSE MEDIATED MRNA DECAY; ONSET AGE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN PROCESSING;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; HUMANS; PRESENILINS; PROTEOLYSIS;

EID: 84869414387     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/hsz-2012-0140     Document Type: Conference Paper

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