Development of scalable manufacturing routes to AZD1981. Application of the Semmler-Wolff aromatisation for synthesis of the indole-4-amide Core

Organic Process Research and Development

Volumn 16, Issue 11, 2012, Pages 1746-1753

  Sulur, Manjunatha ^a   Sharma, Parhalad ^a   Ramakrishnan, Ravi ^a   Naidu, Ravi ^a   Merifield, Eric ^a   Gill, Duncan M ^a,b   Clarke, Adrian M ^a   Thomson, Colin ^a   Butters, Michael ^a   Bachu, Sreekanth ^a   Benison, Colin H ^a   Dokka, Nagaraju ^a   Fong, Emily R ^a   Hose, David R J ^a   Howell, Gareth P ^a   Mobberley, Siobhan E ^a   Morton, Simon C ^a   Mullen, Alexander K ^a   Rapai, Jayan ^a   Tejas, Bharathi ^a  

^a ASTRAZENECA   (United Kingdom)

^b UNIVERSITY OF HUDDERSFIELD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EFFICIENT SYNTHESIS; PYRROLE RING;

AROMATIC COMPOUNDS; CHLORINE COMPOUNDS; KETONES; SYNTHESIS (CHEMICAL);

AMIDES;

EID: 84869408836     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op300173z     Document Type: Article

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