Cyclic stretch-induced thrombin generation by rat vascular smooth muscle cells is mediated by the integrin αvβ3 pathway

Cardiovascular Research

Volumn 96, Issue 3, 2012, Pages 513-523

  Mao, Xianqing ^a,b   Said, Rose ^a,b   Louis, Huguette ^a,b   Max, Jean Pierre ^a,b   Bourhim, Mustapha ^a,b   Challande, Pascal ^c   Wahl, Denis ^a,b   Li, Zhenlin ^c   Regnault, Veronique ^a,b   Lacolley, Patrick ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ DE LORRAINE   (France)

^c SORBONNE UNIVERSITÉ   (France)

Author keywords

Integrin; Mechanical stretch; Signal transduction; Thrombin generation; Vascular smooth muscle cell

Indexed keywords

C ARGINYLGLYCYLASPARTYLPROLYLVALINE; PEPTIDE; PROTEIN TYROSINE KINASE; PROTHROMBIN; SMALL INTERFERING RNA; TALIN; THROMBIN; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR;

ANIMAL CELL; AORTA; APOPTOSIS; ARTICLE; BIOMECHANICS; CELL CULTURE; CELL SURFACE; CONTROLLED STUDY; CYCLIC MECHANICAL STRETCH; CYTOPLASM; MUSCLE STRETCHING; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; RAT; SMOOTH MUSCLE FIBER; UPREGULATION; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

ANIMALS; AORTA; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; INTEGRIN ALPHAVBETA3; MECHANOTRANSDUCTION, CELLULAR; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PEPTIDES, CYCLIC; PHOSPHORYLATION; PROTHROMBIN; PULSATILE FLOW; RATS; RATS, WISTAR; RNA INTERFERENCE; SRC-FAMILY KINASES; STRESS, MECHANICAL; TALIN; THROMBIN; TIME FACTORS; TRANSFECTION; UP-REGULATION;

EID: 84869385283     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvs274     Document Type: Article

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