Predictive values of platinum-related gene polymorphisms in gastric cancer patients on oxaliplatin-based adjuvant chemotherapy

National Medical Journal of China

Volumn 91, Issue 4, 2011, Pages 256-259

  Liu, Yong Ping ^a   Ling, Yang ^a   Zhang, Ya Ping ^a   Liu, Bao Rui ^b  

^a SOOCHOW UNIVERSITY   (China)

^b NONE

Author keywords

Chemotherapy, adjuvant; Polymorphism, single nucleotide; Prognosis; Stomach neoplasms

Indexed keywords

OXALIPLATIN; DNA BINDING PROTEIN; ENDONUCLEASE; ERCC1 PROTEIN, HUMAN; GLUTATHIONE TRANSFERASE P1; GSTP1 PROTEIN, HUMAN; PLATINUM; PLATINUM COMPLEX; X-RAY REPAIR CROSS COMPLEMENTING PROTEIN 1; XRCC1 PROTEIN;

ALLELE; ARTICLE; CANCER ADJUVANT THERAPY; CANCER RECURRENCE; CANCER SURVIVAL; GENE FREQUENCY; GENE SEQUENCE; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MULTIPLE CYCLE TREATMENT; OVERALL SURVIVAL; PREDICTIVE VALUE; REAL TIME POLYMERASE CHAIN REACTION; RECURRENCE FREE SURVIVAL; SINGLE NUCLEOTIDE POLYMORPHISM; STOMACH CANCER; ADJUVANT CHEMOTHERAPY; FEMALE; GENETICS; MALE; MIDDLE AGED; STOMACH TUMOR;

CHEMOTHERAPY, ADJUVANT; DNA-BINDING PROTEINS; ENDONUCLEASES; FEMALE; GENOTYPE; GLUTATHIONE S-TRANSFERASE PI; HUMANS; MALE; MIDDLE AGED; ORGANOPLATINUM COMPOUNDS; PLATINUM; POLYMORPHISM, SINGLE NUCLEOTIDE; PREDICTIVE VALUE OF TESTS; STOMACH NEOPLASMS;

EID: 84869234491     PISSN: 03762491     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0376-2491.2011.04.010     Document Type: Article

References (6)

1. 2009, 89: 3261-3265.
2. Park D J, Lenz H J. Determinants of chemosensitivity in gastric cancer. Curr Opin Pharmacol, 2006, 6:337-344.
3. Park D J, Stoehlmacher J, Zhang W, et al. A Xeroderma pigmentosum group D gene polymorphism predicts clinical outcome to platinum-based chemotherapy in patients with advanced colorectal cancer. Cancer Res, 2001, 61: 8654-8658.
4. Su D, Ma S, Liu P, et al. Genetic polymorphisms and treatment response in advanced non-small cell lung cancer. Lung Cancer, 2007, 56: 281-288.
5. Liang J, Jiang T, Yao R Y, et al. The combination of ERCC1 and XRCC1 gene polymorphisms better predicts clinical outcome to oxaliplatin-based chemotherapy in metastatic colorectal cancer. Cancer Chemother Pharmacol, 2010, 66:493-500.
6. Chen Y C, Tzeng C H, Chen P M, et al. Influence of GSTP1 I105V polymorphism on cumulative neuropathy and outcome of FOLFOX-4 treatment in Asian patients with colorectal carcinoma. Cancer Sci, 2010, 101:530-535.