A herpes simplex virus 2 Glycoprotein D mutant generated by bacterial artificial chromosome mutagenesis is severely impaired for infecting neuronal cells and infects only vero cells expressing exogenous HVEM

Journal of Virology

Volumn 86, Issue 23, 2012, Pages 12891-12902

  Wang, Kening ^a   Kappel, Justin D ^a   Canders, Caleb ^a   Davila, Wilmer F ^a   Sayre, Dean ^a   Chavez, Mayra ^a   Pesnicak, Lesley ^a   Cohen, Jeffrey I ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN D; NECTIN 1; PROTEIN HVEM; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; BRAIN INFECTION; CELL SPREADING; CONTROLLED STUDY; EPITHELIUM CELL; FEMALE; GENE DISRUPTION; GENE INSERTION; GENETIC TRANSDUCTION; HERPES SIMPLEX VIRUS 2; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHOCYTE COUNT; MOLECULAR CLONING; MOLECULAR MODEL; MOUSE; MUTAGENESIS; MUTATIONAL ANALYSIS; NONHUMAN; PHENOTYPIC VARIATION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; VERO CELL; VIRUS EXPRESSION; VIRUS GENOME; VIRUS INFECTIVITY; VIRUS REACTIVATION; VIRUS REPLICATION;

ANIMALS; CELL ADHESION MOLECULES; CELL LINE; CERCOPITHECUS AETHIOPS; CHROMOSOMES, ARTIFICIAL, BACTERIAL; HERPESVIRUS 2, HUMAN; HUMANS; MICE; MICE, INBRED BALB C; MUTAGENESIS; NEURONS; OLIGONUCLEOTIDES; POINT MUTATION; POLYMERASE CHAIN REACTION; RECEPTORS, TUMOR NECROSIS FACTOR, MEMBER 14; VERO CELLS; VIRAL ENVELOPE PROTEINS; VIRUS INTERNALIZATION;

BACTERIA (MICROORGANISMS); HUMAN HERPESVIRUS 2; MUS; SIMPLEXVIRUS;

EID: 84869208405     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01055-12     Document Type: Article

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