Effective treatment of traumatic brain injury: Learning from experience

JAMA

Volumn 308, Issue 19, 2012, Pages 2032-2033

  Ruff, Robert L ^a,b   Riechers II, Ronald G ^a  

^a LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMANTADINE; CITICOLINE;

AGING; BRAIN ISCHEMIA; DISEASE SEVERITY; DRUG EFFICACY; EDITORIAL; HUMAN; INCIDENCE; MORBIDITY; MORTALITY; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; TRAUMATIC BRAIN INJURY;

EID: 84869200824     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.2012.14008     Document Type: Editorial

References (15)

1. Zafonte RD, Bagiella E, Ansel BM, et al. Effect of citicoline on functional and cognitive status among patients with traumatic brain injury: Citicoline Brain Injury Treatment Trial (COBRIT). JAMA. 2012;308(19):1993-2000.
2. Corrigan JD, Selassie AW, Orman JA. The epidemiology of traumatic brain injury. J Head Trauma Rehabil. 2010;25(2):72-80.
3. Leibson CL, Brown AW, Ransom JE, et al. Incidence of traumatic brain injury across the full disease spectrum: a population-based medical record review study. Epidemiology. 2011;22(6):836-844.
4. Coronado VG, Xu L, Basavaraju SV, et al; Centers for Disease Control and Prevention (CDC). Surveillance for traumatic brain injury-related deaths - United States, 1997-2007. MMWR Surveill Summ. 2011;60(5):1-32.
5. Terrio H, Brenner LA, Ivins BJ, et al. Traumatic brain injury screening: preliminary findings in a US Army Brigade Combat Team. J Head Trauma Rehabil. 2009;24(1):14-23.
6. Ruff RL, Riechers RG II, Wang X-F, Piero T, Ruff SS. A case-control study examining whether neurological deficits and PTSD in combat veterans are related to episodes of mild TBI. BMJ Open. 2012;2(2):e000312.
7. Ruff RL, Riechers RG, Ruff SS. Relationships between mild traumatic brain injury sustained in combat and post-traumatic stress disorder. F1000 Med Rep. 2010;2:64.
8. Nyein MK, Jason AM, Yu L, et al. In silico investigation of intracranial blast mitigation with relevance to military traumatic brain injury. Proc Natl Acad Sci U S A. 2010;107(48):20703-20708.
9. Schiff ND, Giacino JT, Kalmar K, et al. Behavioural improvements with thalamic stimulation after severe traumatic brain injury [published correction appears in Nature. 2008;452(7183):120]. Nature. 2007;448(7153):600-603.
10. Giacino JT, Whyte J, Bagiella E, et al. Placebo-controlled trial of amantadine for severe traumatic brain injury. N Engl J Med. 2012;366(9):819-826.
11. Adibhatla RM, Hatcher JF, Dempsey RJ. Citicoline: neuroprotective mechanisms in cerebral ischemia. J Neurochem. 2002;80(1):12-23.
12. Bustamante A, Giralt D, Garcia-Bonilla L, Campos M, Rosell A, Montaner J. Citicoline in pre-clinical animal models of stroke: a meta-analysis shows the optimal neuroprotective profile and the missing steps for jumping into a stroke clinical trial [published online August 23, 2012]. J Neurochem. doi:10.1111/j.1471-4159.2012.07891.x.
13. Diederich K, Frauenknecht K, Minnerup J, et al. Citicoline enhances neuroregenerative processes after experimental stroke in rats. Stroke. 2012;43(7):1931-1940.
14. Dávalos A, Alvarez-Sabín J, Castillo J, et al; International Citicoline Trial on acUte Stroke (ICTUS) Trial Investigators. Citicoline in the treatment of acute ischaemic stroke: an international, randomised, multicentre, placebo-controlled study (ICTUS trial). Lancet. 2012;380(9839):349-357.
15. Andriessen TM, Jacobs B, Vos PE. Clinical characteristics and pathophysiological mechanisms of focal and diffuse traumatic brain injury. J Cell Mol Med. 2010;14(10):2381-2392.