Antiviral activity of acidic polysaccharides from Coccomyxa gloeobotrydiformi, a green alga, against an in vitro human influenza A virus infection

Immunopharmacology and Immunotoxicology

Volumn 35, Issue 1, 2013, Pages 1-7

  Komatsu, Takayuki ^a   Kido, Nobuo ^b   Sugiyama, Tsuyoshi ^c   Yokochi, Takashi ^a  

^a AICHI MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

^c GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Acidic polysaccharide; Antiviral activity; Coccomyxa; Green algae; Influenza A virus

Indexed keywords

ALGAL EXTRACT; ANTIVIRUS AGENT; COCCOMYXA GLOEOBOTRYDIFORMI EXTRACT; POLYSACCHARIDE; UNCLASSIFIED DRUG;

1977 RUSSIAN INFLUENZA; ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CELL STRAIN; COCCOMYXA GLOEOBOTRYDIFORMI; CONTROLLED STUDY; DRUG CYTOTOXICITY; GREEN ALGA; HEMAGGLUTINATION; HEMOLYSIS; IC 50; IN VITRO STUDY; INFLUENZA VACCINATION; INFLUENZA VIRUS A H1N1; INFLUENZA VIRUS A H2N2; INFLUENZA VIRUS A H3N2; NONHUMAN; PANDEMIC INFLUENZA; PRIORITY JOURNAL; VIRUS STRAIN;

ANIMALS; ANTIVIRAL AGENTS; CELLS, CULTURED; CHICKENS; CHLOROPHYTA; DOGS; ERYTHROCYTES; HEMAGGLUTINATION; HEMOLYSIS; HOST-PATHOGEN INTERACTIONS; HUMANS; INFLUENZA A VIRUS; INFLUENZA, HUMAN; MADIN DARBY CANINE KIDNEY CELLS; PLANT EXTRACTS; POLYSACCHARIDES; VIRUS REPLICATION;

CHLOROPHYTA; INFLUENZA A VIRUS; ORTHOMYXOVIRIDAE;

EID: 84869197370     PISSN: 08923973     EISSN: 15322513     Source Type: Journal    
DOI: 10.3109/08923973.2012.710636     Document Type: Article

References (30)

1. Tanaka, K., Tomita, Y., Tsuruta, M., Konishi, F., Okuda, M., Himeno, K., Nomoto, K. Oral administration of Chlorella vulgaris augments concomitant antitumor immunity. Immunopharmacol Immunotoxicol 1990, 12, 277-291.
2. Miyazawa, Y., Murayama, T., Ooya, N., Wang, L.F., Tung, Y.C., Yamaguchi, N. Immunomodulation by a unicellular green algae (Chlorella pyrenoidosa) in tumor-bearing mice. J Ethnopharmacol 1988, 24, 135-146.
3. Konishi, F., Tanaka, K., Himeno, K., Taniguchi, K., Nomoto, K. Antitumor effect induced by a hot water extract of Chlorella vulgaris (CE): Resistance to Meth-A tumor growth mediated by CE-induced polymorphonuclear leukocytes. Cancer Immunol Immunother 1985, 19, 73-78.
4. Kralovec, J.A., Metera, K.L., Kumar, J.R., Watson, L.V., Girouard, G.S., Guan, Y., Carr, R.I., Barrow, C.J., Ewart, H.S. Immunostimulatory principles from Chlorella pyrenoidosaYpart 1: Isolation and biological assessment in vitro. Phytomedicine 2007, 14, 57-64.
5. Tanaka, K., Konishi, F., Himeno, K., Taniguchi, K., Nomoto, K. Augmentation of antitumor resistance by a strain of unicellular green algae, Chlorella vulgaris. Cancer Immunol Immunother 1984, 17, 90-94.
6. Pugh, N., Ross, S.A., ElSohly, H.N., ElSohly, M.A., Pasco, D.S. Isolation of three high molecular weight polysaccharide preparations with potent immunostimulatory activity from Spirulina platensis, aphanizomenon flos-aquae and Chlorella pyrenoidosa. Planta Med 2001, 67, 737-742.
7. Cheng, F.C., Lin, A., Feng, J.J., Mizoguchi, T., Takekoshi, H., Kubota, H., Kato, Y., Naoki, Y. Effects of chlorella on activities of protein tyrosine phosphatases, matrix metalloproteinases, caspases, cytokine release, B and T cell proliferations, and phorbol ester receptor binding. J Med Food 2004, 7, 146-152.
8. Diamant, A., Lipshitz, A., Ucko, M. Phylogeny of Coccomyxa (Myxosporea: Myxidiidae) spp. with the description of a new species from Bathygobius cyclopterus (Gobiidae) in the northern Red Sea. Folia Parasitol 2007, 54, 109-116.
9. Crespo, C., Rodríguez, H., Segade, P., Iglesias, R., García-Estévez, J.M. Coccomyxa sp. (chlorophyta: chlorococcales), a new pathogen in mussels (Mytilus galloprovincialis) of Vigo estuary (Galicia, NW Spain). J Invertebr Pathol 2009, 102, 214-219.
10. Dubois, M., Gilles, K., Hamilton, J., Rebers, P., Smith, F. Colorimetric method for determination of sugars and related substances. Anal Chem 1956, 28, 350-356.
11. Vanderlinden, E., Göktas, F., Cesur, Z., Froeyen, M., Reed, M.L., Russell, C.J., Cesur, N., Naesens, L. Novel inhibitors of influenza virus fusion: Structure-activity relationship and interaction with the viral hemagglutinin. J Virol 2010, 84, 4277-4288.
12. Steinhauer, D.A., Sauter, N.K., Skehel, J.J., Wiley, D.C. Receptor binding and cell entry by influenza viruses. SeminVirol 1992, 3, 91-100.
13. Weis, W., Brown, J.H., Cusack, S., Paulson, J.C., Skehel, J.J., Wiley, D.C. Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acid. Nature 1988, 333, 426-431.
14. Wilson, I.A., Skehel, J.J., Wiley, D.C. Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 A resolution. Nature 1981, 289, 366-373.
15. Helenius, A. Unpacking the incoming influenza virus. Cell 1992, 69, 577-578.
16. Stegmann, T., Delfino, J.M., Richards, F.M., Helenius, A. The HA2 subunit of influenza hemagglutinin inserts into the target membrane prior to fusion. J Biol Chem 1991, 266, 18404-18410.
17. Stegmann, T., Doms, R.W., Helenius, A. Protein-mediated membrane fusion. Annu Rev Biophys Biophys Chem 1989, 18, 187-211.
18. Stegmann, T., White, J.M., Helenius, A. Intermediates in influenza induced membrane fusion. EMBO J 1990, 9, 4231-4241.
19. Wiley, D.C., Skehel, J.J. The structure and function of the hemagglutinin membrane glycoprotein of influenza virus. Annu Rev Biochem 1987, 56, 365-394.
20. White, J.M. Viral and cellular membrane fusion proteins. Annu Rev Physiol 1990, 52, 675-697.
21. White, J.M. Membrane fusion. Science 1992, 258, 917-924.
22. Webster, R.G., Bean, W.J., Gorman, O.T., Chambers, T.M., Kawaoka, Y. Evolution and ecology of influenza A viruses. Microbiol Rev 1992, 56, 152-179.
23. Nobusawa, E., Aoyama, T., Kato, H., Suzuki, Y., Tateno, Y., Nakajima, K. Comparison of complete amino acid sequences and receptorbinding properties among 13 serotypes of hemagglutinins of influenza A viruses. Virology 1991, 182, 475-485.
24. Honegger, R., Brunner, U. Sporopollenin in the cell walls of Coccomyxa and Myrmecia phycobionts of various lichens: An ultrastructural and chemical investigation. Can J Bot 1981, 59, 2713-2734.
25. Hayashi, K., Hayashi, T., Kojima, I. A natural sulfated polysaccharide, calcium spirulan, isolated from Spirulina platensis: In vitro and ex vivo evaluation of anti-herpes simplex virus and anti-human immunodeficiency virus activities. AIDS Res Hum Retroviruses 1996, 12, 1463-1471.
26. Lee, J.B., Hayashi, T., Hayashi, K., Sankawa, U. Structural analysis of calcium spirulan (Ca-SP)-derived oligosaccharides using electrospray ionization mass spectrometry. J Nat Prod 2000, 63, 136-138.
27. Kanekiyo, K., Hayashi, K., Takenaka, H., Lee, J.B., Hayashi, T. Antiherpes simplex virus target of an acidic polysaccharide, nostoflan, from the edible blue-green alga Nostoc flagelliforme. Biol Pharm Bull 2007, 30, 1573-1575.
28. Lee, J.B., Hayashi, K., Hashimoto, M., Nakano, T., Hayashi, T. Novel antiviral fucoidan from sporophyll of Undaria pinnatifida (Mekabu). Chem Pharm Bull 2004, 52, 1091-1094.
29. Lee, J.B., Hayashi, K., Hirata, M., Kuroda, E., Suzuki, E., Kubo, Y., Hayashi, T. Antiviral sulfated polysaccharide from Navicula directa, a diatom collected from deep-sea water in Toyama Bay. Biol Pharm Bull 2006, 29, 2135-2139.
30. Kanekiyo, K., Hayashi, K., Lee, J.B., Takenaka, H., Hayashi, T. [Structure and antiviral activity of an acidic polysaccharide from an edible blue-green alga, Nostoc flagelliforme]. Yakugaku Zasshi 2008, 128, 725-731.