Synthesis, radiolabeling, and preclinical evaluation of a new octreotide analog for somatostatin receptor-positive tumor scintigraphy

Journal of Peptide Science

Volumn 18, Issue 12, 2012, Pages 720-730

  De, Kakali ^a   Bhowmik, Arijit ^a   Behera, Ashok ^a   Banerjee, Indranil ^a   Ghosh, Mrinal Kanti ^a   Misra, Mridula ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

Author keywords

99mTc; C6 glioma; HYNIC; Octreotide; Somatostatin receptor

Indexed keywords

6 HYDRAZINOPYRIDINE 3 CARBOXYLIC ACID SERINE OCTREOTATE; N,N' BIS(2 HYDROXYBENZYL)ETHYLENEDIAMINE N,N' DIACETIC ACID; PERTECHNETIC ACID TC 99M; RADIOPHARMACEUTICAL AGENT; SOMATOSTATIN RECEPTOR 2; TECHNETIUM 99M; UNCLASSIFIED DRUG; OCTREOTIDE; PROTEIN BINDING; SOMATOSTATIN RECEPTOR; SSTR2 PROTEIN, RAT; TECHNETIUM 99M 6-HYDRAZINOPYRIDINE-3-CARBOXYLIC ACID-SER3-OCTREOTATE; TECHNETIUM COMPLEX;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BRAIN CORTEX; CANCER GROWTH; CELL MEMBRANE; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; GLIOMA; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; INTERNALIZATION; INTRACRANIAL TUMOR; ISOTOPE LABELING; NONHUMAN; PARTITION COEFFICIENT; PLASMA CLEARANCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; RADIOACTIVITY; RAT; RECEPTOR BINDING; SOLID; TUMOR SCINTISCANNING; ANALOGS AND DERIVATIVES; ANIMAL; BRAIN TUMOR; CANCER TRANSPLANTATION; DIAGNOSTIC USE; METABOLISM; SCINTISCANNING; SPRAGUE DAWLEY RAT; SYNTHESIS; TISSUE DISTRIBUTION; TUMOR CELL LINE;

RATTUS;

ANIMALS; BRAIN NEOPLASMS; CELL LINE, TUMOR; FEMALE; GLIOMA; NEOPLASM TRANSPLANTATION; OCTREOTIDE; ORGANOTECHNETIUM COMPOUNDS; PROTEIN BINDING; RADIOPHARMACEUTICALS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SOMATOSTATIN; TISSUE DISTRIBUTION;

EID: 84869175246     PISSN: 10752617     EISSN: 10991387     Source Type: Journal    
DOI: 10.1002/psc.2458     Document Type: Article

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