Oral cholestyramine is not an effective treatment for uncomplicated erythropoietic protoporphyria

Journal of the American Academy of Dermatology

Volumn 67, Issue 6, 2012, Pages 1383-1384

  Tewari, Angela ^a   Marsden, Joanna ^b   Naik, Harsha ^a   Benton, Emma C ^a   Sarkany, Robert ^a  

^a ST THOMAS HOSPITAL   (United Kingdom)

^b KING'S COLLEGE HOSPITAL NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED CARBON; COLESTYRAMINE; PROTOPORPHYRIN;

DRUG EFFICACY; ERYTHROCYTE; ERYTHROPOIETIC PROTOPORPHYRIA; HUMAN; LETTER; LIVER FUNCTION TEST; PRIORITY JOURNAL;

EID: 84869130094     PISSN: 01909622     EISSN: 10976787     Source Type: Journal    
DOI: 10.1016/j.jaad.2012.02.006     Document Type: Article

References (5)

1. A.J. McCullough, D. Barron, K.D. Mullen, M. Petrelli, M.C. Park, and H. Mukhtar Fecal protoporphyrin excretion in erythropoietic protoporphyria: effect of cholestyramine and bile acid feeding Gastroenterology 94 1988 177 181
2. G.J. Beukeveld, and B.G. Wolthers Cholestyramine orally administered to patients with erythropoietic protoporphyria results in urinary excretion of protoporphyrin: to be explained by the Herbst-Volkheimer effect? Clin Chim Acta 233 1-2 1995 119 126
3. A. Gorchein, and G.R. Foster Liver failure in protoporphyria: long-term treatment with oral charcoal Hepatology 29 1999 995 996
4. E.I. Minder, X. Schneider-Yin, and F. Moll Lack of effect of oral charcoal in congenital erythropoietic porphyria N Engl J Med 330 1994 1092 1094
5. R.J. Hift, G. Todd, P.N. Meissner, and R.E. Kirsch Administration of oral activated charcoal in variegate porphyria results in a paradoxical clinical and biochemical deterioration Br J Dermatol 149 2003 1266 1269