Introduction of β-Carotene-Rich orange sweet potato in rural Uganda resulted in increased vitamin a intakes among children and women and improved vitamin a status among children

Journal of Nutrition

Volumn 142, Issue 10, 2012, Pages 1871-1880

  Hotz, Christine ^a   Loechl, Cornelia ^b   Lubowa, Abdelrahman ^c   Tumwine, James K ^d   Masawi, Grace Ndeezi ^d,e   Baingana, Rhona ^e   Carriquiry, Alicia ^f   de Brauw Meenakshi, Alan ^a   Gilligan, Daniel O ^a  

^a INTERNATIONAL FOOD POLICY RESEARCH INSTITUTE   (United States)

^b International Potato Center   (Uganda)

^c CIAT Uganda   (Uganda)

^d Department of Epidemiology and Molecular Microbiology Immunology   (Uganda)

^e MAKERERE UNIVERSITY   (Uganda)

^f Department of Statistics Center for Statistics and Applications in Forensic Evidence Iowa State University 2438 Osborn Dr Ames   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CAROTENE; RETINOL;

ANTHROPOMETRY; ARTICLE; BLOOD LEVEL; CHILD; CHILD NUTRITION; DIETARY INTAKE; FEMALE; HEALTH PROMOTION; HUMAN; INFANT; NUTRITIONAL ASSESSMENT; NUTRITIONAL STATUS; NUTRITIONAL VALUE; ORANGE SWEET POTATO; PRESCHOOL CHILD; RETINOL DEFICIENCY; ROOT VEGETABLE; RURAL AREA; UGANDA;

ADULT; ANTHROPOMETRY; BETA CAROTENE; CHILD, PRESCHOOL; CROSS-SECTIONAL STUDIES; FAMILY CHARACTERISTICS; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFANT; IPOMOEA BATATAS; MALE; NUTRITION ASSESSMENT; NUTRITIONAL STATUS; REGRESSION ANALYSIS; RURAL POPULATION; UGANDA; VITAMIN A; VITAMIN A DEFICIENCY;

IPOMOEA BATATAS;

EID: 84869111111     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.111.151829     Document Type: Article

References (39)

1. WHO. Global prevalence of vitamin A deficiency in populations at risk 1995-2005. WHO Global Database on Vitamin A Deficiency. Geneva: WHO; 2009.
2. Black RE, Allen LH, Bhutta ZA, Caulfield LE, de Onis M, Ezzati M, Mathers C, Rivera J, Maternal and Child Undernutrition Study Group. Maternal and child undernutrition: global and regional exposures and health consequences. Lancet. 2008;371:243-60.
3. Beaton GH, Martorell R, Aronson KJ, Edmonston B, McCabe G, Ross AC, Harvey B. Effectiveness of vitamin A supplementation in the control of young child morbidity and mortality in developing countries. United Nations Administrative Committee on Coordination, Sub-committee on Nutrition State-of-the-Art Series: nutrition policy discussion paper no. 13. Geneva: United Nations; 1993.
4. WHO. Vitamin A deficiency and xerophthalmia. Report of a joint WHO/USAID meeting. WHO Technical Report Series 590. Geneva: WHO; 1976.
5. West KP Jr, Gernand A, Sommer A. Vitamin A in nutritional anemia. In: Kraemer K, Zimmermann MB, editors. Nutritional anemia. Basel: Sight and Life Press; 2007. p. 133-53.
6. Christian P, West KP Jr, Khatry SK, Katz J, LeClerq S, Kimbrough Pradhan E, Shrestha SR. Vitamin A or b-carotene supplementation reduces but does not eliminate maternal night blindness in Nepal. J Nutr. 1998;128:1458-63.
7. Bouis HE, Hotz C, McClafferty B, Meenakshi JV, Pfeiffer W. Biofortification: a new tool to reduce micronutrient malnutrition. Food Nutr Bull. 2011;32:S31-40.
8. Uganda Bureau of Statistics and ORC Macro. Uganda Demographic and Health Survey, 2000-2001. Calverton (MD): UBOS and ORC Macro; 2001.
9. UNICEF. State of the world's children. Special edition. Statistical tables. New York: UNICEF; 2009.
10. Allen LH, Haskell M. Estimating the potential for vitamin A toxicity in women and young children. J Nutr. 2002;132:S2907-19.
11. Harvey P, Rambeloson Z, Dary O. The 2008 Uganda food consumption survey. Determining the dietary patterns of Ugandan women and children. Washington, DC: Academy for Educational Development; 2010.
12. FAO. FAOSTAT food balance sheets. Rome; 2007 [cited 2010 Oct 11]. Available from: http://faostat.fao.org/site/368/DesktopDefault.aspx?PageID=368#ancor.
13. Takahata Y, Noda T, Nagata T. HPLC determination of b-carotene content of sweet potato cultivars and its relationship with color values. Japan J Breed. 1993;43:421-7.
14. Jalal F, Nesheim MC, Agus Z, Sanjur D, Habicht JP. Serum retinol concentrations in children are affected by food sources of b-carotene, fat intake, and anthelmintic drug treatment. Am J Clin Nutr. 1998; 68:623-9.
15. Haskell MJ, Jamil KM, Hassan F, Peerson JM, Hossain MI, Fuchs GJ, Brown KH. Daily consumption of Indian spinach (Basella alba) or sweet potatoes has a positive effect on total-body vitamin A stores in Bangladeshi men. Am J Clin Nutr. 2004;80:705-14.
16. van Jaarsveld PJ, Faber M, Tanumihardjo SA, Nestel P, Lombard CJ, Spinnler Benade AJ. b-Carotene-rich orange-fleshed sweet potato improves the vitamin A status of primary school children assessed with the modified-relative-dose-response test. Am J Clin Nutr. 2005; 81:1080-7.
17. Low JW, Arimond M, Osman N, Dunguara B, Zano F, Tschirley D. Orange-fleshed sweet potatoes increased vitamin A intake and serum retinol concentrations in young children in rural Mozambique. J Nutr. 2007;137:1320-7.
18. Gibson RS, Ferguson EL. An interactive 24-hour recall for assessing the adequacy of iron and zinc intakes in developing countries. HarvestPlus technical monograph 8. Washington, DC: HarvestPlus; 2008.
19. Hotz C, Abdelrahman L, Sison C, Moursi M, Loechl C. A food composition table for central and eastern Uganda. Washington, DC: HarvestPlus; 2011.
20. USDA, Agricultural Research Service, USDA Nutrient Data Laboratory. USDA National Nutrient Database for Standard Reference, release 21. Beltsville (MD): USDA; 2008.
21. Food and Nutrition Board, Institute of Medicine. Dietary reference intakes: applications in dietary assessment. Washington, DC: National Academy Press; 2000.
22. Nusser SM, Carriquiry AL, Dodd KW, Fuller WA. A semi-parametric approach to estimating usual nutrient intake distributions. J Am Stat Assoc. 1996;91:1440-9.
23. Fuller WA. Measurement error models. New York: Wiley, 1987.
24. Food and Nutrition Board and Institute of Medicine. Vitamin A. In: Dietary Reference Intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. Washington, DC: National Academy Press; 2001.
25. Bengtsson A, Namuebi A, Larsson Alminger M, Svanberg U. Effects of various traditional processing methods on the all-trans-b-carotene content of orange-fleshed sweet potato. J Food Compost Anal. 2008;21:134-43.
26. Thurnham DI, McCabe GP, Northrop-Clewes CA, Nestel P. Effects of subclinical infection on plasma retinol concentrations and assessment of prevalence of vitamin A deficiency: meta-analysis. Lancet. 2003;362: 2052-8.
27. Craft NE, Furr HC, Price L. Vitamin A in dried blood spots: update on HPLC method changes to measure retinol. Abstract T57. Washington, DC: Micronutrient Forum; 2007.
28. WHO Multicentre Growth Reference Study Group. WHO child growth standards: length/height-for-age, weight-for-age, weight-for-length, weight-for-height and body mass index-for-age: methods and development. Geneva: WHO; 2006.
29. Pilch SM. Analysis of vitamin A data from health and nutrition examination surveys. J Nutr. 1987;117:636-40.
30. Box GEP, Cox DR. An analysis of transformations. J R Stat Soc Series B Stat Methodol. 1964;26:211-52.
31. Tomlins K, Ndunguru B, Stambul K, Joshua N, Ngendello T, Rwiza E, Amour R, Ramadhani B, Kapande A, Westby A. Sensory evaluation and consumer acceptability of pale-fleshed and orange-fleshed sweetpotato by school children and mothers with preschool children. J Sci Food Agric. 2007;87:2436-46.
32. Chowdhury S, Meenakshi JV, Tomlins KI, Owori C. Are consumers in developing countries willing to pay for micronutrient-dense biofortified foods? Evidence from a field experiment in Uganda. Am J Agric Econ. 2011;93:83-97.
33. WHO. Complementary feeding of young children in developing countries: a review of current scientific knowledge. Brown KH, Dewey K, Allen L, editors. Geneva: WHO; 1998.
34. de Pee S, West CE, Permaesih D, Martuti S, Muhilal, Hautvast JGAJ. Orange fruit is more effective than are dark-green, leafy vegetables in increasing serum concentrations of retinol and b-carotene in schoolchildren in Indonesia. Am J Clin Nutr. 1998;68:1058-67.
35. Tang G, Gu X-F, Hu S-M, Su Q-M, Qin J, Dolnikowski GG, Fjeld CR, Gao X, Russell RM, Yin S-A. Green and yellow vegetables can maintain body stores of vitamin A in Chinese children. Am J Clin Nutr. 1999;70:1069-76.
36. Vuong T, Dueker SR, Murphy SP. Plasma b-carotene and retinol concentrations of children increase after a 30-d supplementation with the fruit Momordica cochinchinensis (gac). Am J Clin Nutr. 2002; 75:872-9.
37. Faber M, Phungula MAS, Venter SL, Dhansay MA, Spinnler Benade AJ. Home gardens focusing on the production of yellow and dark-green leafy vegetables increase the serum retinol concentrations of 2-5 y-old children in South Africa. Am J Clin Nutr. 2002;76:1048-54.
38. Miller M, Humphrey J, Johnson E, Marinda E, Brookmeyer R, Katz J. Why do children become vitamin A deficient? J Nutr. 2002;132:S2867-80.
39. Uganda Bureau of Statistics and Macro International Inc. Uganda demographic and health survey 2006. Calverton (MD): UBOS and Macro International Inc; 2007.