Effect of the PPARG2 Pro12Ala polymorphism and clinical risk factors for diabetes mellitus on HbA1c in the Japanese general population

Journal of Epidemiology

Volumn 22, Issue 6, 2012, Pages 523-531

  Hara, Megumi ^a   Higaki, Yasuki ^b   Taguchi, Naoto ^a   Shinchi, Koichi ^a   Morita, Emi ^c   Naito, Mariko ^c   Hamajima, Nobuyuki ^c   Takashima, Naoyuki ^d   Suzuki, Sadao ^e   Nakamura, Akihiko ^f   Ohnaka, Keizo ^g   Uemura, Hirokazu ^h   Nishida, Hideki ⁱ   Hosono, Satoyo ^j   Mikami, Haruo ^k   Kubo, Michiaki ^l   Tanaka, Hideo ^j  

^a SAGA UNIVERSITY   (Japan)

^b FUKUOKA UNIVERSITY   (Japan)

^c NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^e NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^f KAGOSHIMA UNIVERSITY   (Japan)

^g KYUSHU UNIVERSITY   (Japan)

^h UNIVERSITY OF TOKUSHIMA   (Japan)

ⁱ KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^j AICHI CANCER CENTER HOSPITAL   (Japan)

^k CHIBA CANCER CENTER   (Japan)

^l RIKEN   (Japan)

more..

Author keywords

Glycated hemoglobin; Interaction; Peroxisome proliferator activated receptor 2; Polymorphism

Indexed keywords

GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C PROTEIN, HUMAN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

ADULT; AGED; ARTICLE; CROSS-SECTIONAL STUDY; DIABETES MELLITUS; FEMALE; GENETIC POLYMORPHISM; GENETICS; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; JAPAN; MALE; MIDDLE AGED; RISK FACTOR;

ADULT; AGED; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS; FEMALE; GENE-ENVIRONMENT INTERACTION; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; JAPAN; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; PPAR GAMMA; RISK FACTORS;

EID: 84869108535     PISSN: 09175040     EISSN: 13499092     Source Type: Journal    
DOI: 10.2188/jea.JE20120078     Document Type: Article

References (32)

1. Amos AF, McCarty DJ, Zimmet P. The rising global burden of diabetes and its complications: estimates and projections to the year 2010. Diabet Med. 1997;14 Suppl 5:S1-85.
2. Whiting DR, Guariguata L, Weil C, Shaw J. IDF Diabetes Atlas:Global estimates of the prevalence of diabetes for 2011 and 2030. Diabetes Res Clin Pract. 2011;94(3):311-21.
3. Ministry of Health, Labour and Welfare in Japan. National health and nutrition survey in 2010 (in Japanese). Available from:http://www.mhlw.go.jp/stf/houdou/2r98520000020qbb.html.
4. Reis JP, Loria CM, Sorlie PD, Park Y, Hollenbeck A, Schatzkin A. Lifestyle factors and risk for new-onset diabetes: a population-based cohort study. Ann Intern Med. 2011;155(5):292-9.
5. Permutt MA, Wasson J, Cox N. Genetic epidemiology of diabetes. J Clin Invest. 2005;115(6):1431-9.
6. Lyssenko V, Jonsson A, Almgren P, Pulizzi N, Isomaa B, Tuomi T, et al. Clinical risk factors, DNAvariants, and the development of type 2 diabetes. N Engl J Med. 2008;359(21):2220-32.
7. Gouda HN, Sagoo GS, Harding AH, Yates J, Sandhu MS,Higgins JP. The association between the peroxisome proliferator-activated receptor-gamma2 (PPARG2) Pro12Ala gene variant and type 2 diabetes mellitus: a HuGE review and meta-analysis. Am J Epidemiol. 2010;171(6):645-55.
8. American Diabetes Association. Diagnosis and classification diabetes mellitus. Diabetes Care. 2010;33 Suppl 1:S62-9.
9. Heianza Y, Hara S, Arase Y, Saito K, Fujiwara K, Tsuji H, et al.HbA1c 5.7-6.4% and impaired fasting plasma glucose for diagnosis of prediabetes and risk of progression to diabetes in Japan (TOPICS 3): a longitudinal cohort study. Lancet.2011;378(9786):147-55.
10. Hamajima N; J-MICC Study Group. The Japan Multi-Institutional Collaborative Cohort Study (J-MICC Study) to detect gene-environment interactions for cancer. Asian Pac J Cancer Prev. 2007;8(2):317-23.
11. Wakai K, Hamajima N, Okada R, Naito M, Morita E, Hishida et al. Profile of participants and genotype distributions of 108 polymorphisms in a cross-sectional study of associations of genotypes with lifestyle and clinical factors: a project in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study.J Epidemiol. 2011;21(3):223-35.
12. Tokudome S, Goto C, Imaeda N, Tokudome Y, Ikeda M, Maki S. Development of a data-based short food frequency questionnaire for assessing nutrient intake by middle-aged Japanese. Asian Pac J Cancer Prev. 2004;5(1):40-3.
13. Tokudome Y, Goto C, Imaeda N, Hasegawa T, Kato R, Hirose K, et al. Relative validity of a short food frequency questionnaire for assessing nutrient intake versus three-day weighed diet records in middle-aged Japanese. J Epidemiol. 2005;15(4):135-45.
14. Imaeda N, Goto C, Tokudome Y, Hirose K, Tajima K, Tokudome S. Reproducibility of a short food frequency questionnaire for Japanese general population. J Epidemiol. 2007;17(3):100-7.
15. Kashiwagi A, Kasuga M, Araki E, Oka Y, Hanafusa T,Ito H, et al. International clinical harmonization of glycated hemoglobin in Japan: From Japan Diabetes Society to National Glycohemoglobin Standadization Program Values. J Diabetes Investig. 2012;3(1):39-40.
16. Ohnishi Y, Tanaka T, Ozaki K, Yamada R, Suzuki H, Nakamura Y. A high-throughput SNP typing system for genome-wide association studies. J Hum Genet. 2001;46(8):471-7.
17. Japan Science and Technology Agency. Standard Tables of Food Composition in Japan, Fifth Revised Edition. Tokyo: Ministry of Finance Printing Bureau; 2000 (in Japanese).
18. Michalik L, Auwerx J, Berger JP, Chatterjee VK, Glass CK,Gonzalez FJ, et al. International Union of Pharmacology. LXI.Peroxisome proliferator-activated receptors. Pharmacol Rev.2006;58(4):726-41.
19. Yamauchi T, Kamon J, Waki H, Murakami K, Motojima K,Komeda K, et al. The mechanisms by which both heterozygous peroxisome proliferator-activated receptor gamma(PPARgamma) deficiency and PPARgamma agonist improve insulin resistance. J Biol Chem. 2001;276(44):41245-54.
20. Hara K, Okada T, Tobe K, Yasuda K, Mori Y, Kadowaki H,et al. The Pro12Ala polymorphism in PPAR gamma2 may confer resistance to type 2 diabetes. Biochem Biophys Res Commun.2000;271(1):212-6.
21. González Sánchez JL, Serrano Ríos M, Fernández Perez C,Laakso M, Martínez Larrad MT. Effect of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor gamma-2 gene on adiposity, insulin sensitivity and lipid profile in the Spanish population. Eur J Endocrinol. 2002;147(4):495-501.
22. Li S, Chen W, Srinivasan SR, Boerwinkle E, Berenson GS;Bogalusa Heart Study. The peroxisome proliferator-activated receptor-gamma2 gene polymorphism (Pro12Ala) beneficially influences insulin resistance and its tracking from childhood to adulthood: the Bogalusa Heart Study. Diabetes. 2003;52(5):1265-9.
23. Ghoussaini M, Meyre D, Lobbens S, Charpentier G, Clément K,Charles MA, et al. Implication of the Pro12Ala polymorphism of the PPAR-gamma 2 gene in type 2 diabetes and obesity in the French population. BMC Med Genet. 2005;6:11.
24. Cauchi S, Nead KT, Choquet H, Horber F, Potoczna N, Balkau B, et al. The genetic susceptibility to type 2 diabetes may be modulated by obesity status: implications for association studies.BMC Med Genet. 2008;9:45.
25. Buzzetti R, Petrone A, Ribaudo MC, Alemanno I, Zavarella S,Mein CA, et al. The common PPAR-gamma2 Pro12Ala variant is associated with greater insulin sensitivity. European journal of human genetics. Eur J Hum Genet. 2004;12(12):1050-4.
26. Danaei G, Finucane MM, Lu Y, Singh GM, Cowan MJ,Paciorek CJ, et al. National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2.7 million participants.Lancet. 2011;378(9785):31-40.
27. Morini E, Tassi V, Capponi D, Ludovico O, Dallapiccola B,Trischitta V, et al. Interaction between PPARgamma2 variants and gender on the modulation of body weight. Obesity (Silver Spring). 2008;16(6):1467-70.
28. Fan W, Yanase T, Morinaga H, Mu YM, Nomura M, Okabe T,et al. Activation of peroxisome proliferator-activated receptorgamma and retinoid X receptor inhibits aromatase transcription via nuclear factor-kappaB. Endocrinology. 2005;146(1):85-92.
29. Meisinger C, Thorand B, Schneider A, Stieber J, Döring A, Löwel H. Sex differences in risk factors for incident type 2 diabetes mellitus: the MONICA Augsburg cohort study. Arch Intern Med. 2002;162(1):82-9.
30. Koppes LL, Dekker JM, Hendriks HF, Bouter LM, Heine RJ.Moderate alcohol consumption lowers the risk of type 2 diabetes: a meta-analysis of prospective observational studies.Diabetes Care. 2005;28(3):719-25.
31. Seike N, Noda M, Kadowaki T. Alcohol consumption and risk of type 2 diabetes mellitus in Japanese: a systematic review.Asia Pac J Clin Nutr. 2008;17(4):545-51.
32. Sato KK, Hayashi T, Harita N, Yoneda T, Nakamura Y, Endo G,et al. Combined measurement of fasting plasma glucose and A1C is effective for the prediction of type 2 diabetes: the Kansai Healthcare Study. Diabetes Care. 2009;32(4):644-6.