Skin autofluorescence and risk of micro- and macrovascular complications in patients with Type2 diabetes mellitus-a multi-centre study

Diabetic Medicine

Volumn 29, Issue 12, 2012, Pages 1556-1561

  Noordzij, M J ^a   Mulder, D J ^a   Oomen, P H N ^b   Brouwer, T ^c   Jager, J ^d   Castro Cabezas, M ^e   Lefrandt, J D ^a   Smit, A J ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b MEDICAL CENTER LEEUWARDEN   (Netherlands)

^c ONZE LIEVE VROUWE GASTHUIS   (Netherlands)

^d Department of Internal Medicine   (Netherlands)

^e SINT FRANCISCUS GASTHUIS   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN A1C;

ADULT; AGED; ARTICLE; AUTOFLUORESCENCE; CARDIOVASCULAR RISK; CONTROLLED STUDY; DISEASE DURATION; FEMALE; HEART ATRIUM FIBRILLATION; HUMAN; KIDNEY DISEASE; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY (TOPIC); NEUROPATHY; NON INSULIN DEPENDENT DIABETES MELLITUS; PREDICTIVE VALUE; RETINOPATHY; RISK ASSESSMENT; SEX DIFFERENCE; SKIN; VASCULAR DISEASE;

AGED; BIOLOGICAL MARKERS; BLOOD PRESSURE; BODY MASS INDEX; CARDIOVASCULAR DISEASES; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; FEMALE; FLUORESCENCE; GLYCOSYLATION END PRODUCTS, ADVANCED; HUMANS; MALE; MIDDLE AGED; NETHERLANDS; REPRODUCIBILITY OF RESULTS; RISK FACTORS; SKIN;

EID: 84869098398     PISSN: 07423071     EISSN: 14645491     Source Type: Journal    
DOI: 10.1111/dme.12005     Document Type: Article

References (15)

1. Goldin A, Beckman JA, Schmidt AM, Creager MA. Advanced glycation end products: sparking the development of diabetic vascular injury. Circulation 2006; 114: 597-605.
2. Brownlee M. Advanced protein glycosylation in diabetes and aging. Annu Rev Med 1995; 46: 223-234.
3. Aronson D. Cross-linking of glycated collagen in the pathogenesis of arterial and myocardial stiffening of aging and diabetes. J Hypertens 2003; 21: 3-12.
4. 1c as markers of diabetic complications. DCCT Skin Collagen Ancillary Study Group. Diabetes Control and Complications Trial. Diabetes 1999; 48: 870-880.
5. Genuth S, Sun W, Cleary P, Sell DR, Dahms W, Malone J et al. Glycation and carboxymethyllysine levels in skin collagen predict the risk of future 10-year progression of diabetic retinopathy and nephropathy in the Diabetes Control and Complications Trial and Epidemiology of Diabetes Interventions and Complications participants with type1 diabetes. Diabetes 2005; 54: 3103-3111.
6. Meerwaldt R, Links T, Graaff R, Thorpe SR, Baynes JW, Hartog J et al. Simple non-invasive measurement of skin autofluorescence. Ann N Y Acad Sci 2005; 1043: 290-298.
7. Mulder DJ, Water TV, Lutgers HL, Graaff R, Gans RO, Zijlstra F et al. Skin autofluorescence, a novel marker for glycemic and oxidative stress-derived advanced glycation endproducts: an overview of current clinical studies, evidence, and limitations. Diabetes Technol Ther 2006; 8: 523-535.
8. Meerwaldt R, Graaff R, Oomen PH, Links TP, Jager JJ, Alderson NL et al. Simple non-invasive assessment of advanced glycation endproduct accumulation. Diabetologia 2004; 47: 1324-1330.
9. Lutgers HL, Graaff R, Links TP, Ubink-Veltmaat LJ, Bilo HJ, Gans RO et al. Skin autofluorescence as a noninvasive marker of vascular damage in patients with type2 diabetes. Diabetes Care 2006; 29: 2654-2659.
10. Gerrits EG, Lutgers HL, Kleefstra N, Graaff R, Groenier KH, Smit AJ et al. Skin autofluorescence: a tool to identify type2 diabetic patients at risk for developing microvascular complications. Diabetes Care 2008; 31: 517-521.
11. Lutgers HL, Gerrits EG, Graaff R, Links TP, Sluiter WJ, Gans RO et al. Skin autofluorescence provides additional information to the UK Prospective Diabetes Study (UKPDS) risk score for the estimation of cardiovascular prognosis in type2 diabetes mellitus. Diabetologia 2009; 52: 789-797.
12. Koetsier M, Nur E, Chunmao H, Lutgers HL, Links TP, Smit AJ et al. Skin color independent assessment of aging using skin autofluorescence. Opt Express 2010; 18: 14416-14429.
13. Koetsier M, Lutgers HL, de Jonge C, Links TP, Smit AJ, Graaff R. Reference values of skin autofluorescence. Diabetes Technol Ther 2010; 12: 399-403.
14. Gerrits EG, Lutgers HL, Kleefstra N, Groenier KH, Smit A, Gans ROB et al. Skin advanced glycation end product accumulation is poorly reflected by glycemic control in type2 diabetic patients (ZODIAC9). J Diabetes Sci Technol 2008; 2: 572-577.
15. Chabroux S, Canoui-Poitrine F, Reffet S, Mills-Joncour G, Morelon E, Colin C et al. Advanced glycation end products assessed by skin autofluorescence in type1 diabetics are associated with nephropathy, but not retinopathy. Diabetes Metab 2010; 36: 152-157.