Synthesis of N-phenyl-N-(3-(piperidin-1-yl)propyl)benzofuran-2-carboxamides as new selective ligands for sigma receptors

Bioorganic and Medicinal Chemistry

Volumn 20, Issue 23, 2012, Pages 6856-6861

  Marriott, Karla Sue C ^a   Morrison, Andrew Z ^a   Moore, Misty ^a   Olubajo, Olarongbe ^a   Stewart, Leonard E ^a  

^a SAVANNAH STATE UNIVERSITY   (United States)

Author keywords

Alzheimer's; Benzofuran; Carboxamide; Ligand; Neurodegenerative; Receptor; Sigma

Indexed keywords

3 METHYL N PHENYL N [3 (PIPERIDIN 1 YL)PROPYL]BENZOFURAN 2 CARBOXAMIDE; 3 METHYL N PHENYLBENZOFURAN 2 CARBOXAMIDE; 5,6 DIMETHOXY 3 METHYL N PHENYL N [3 (PIPERIDIN 1 YL)PROPYL]BENZOFURAN 2 CARBOXAMIDE; 5,6 DIMETHOXY 3 METHYL N PHENYLBENZOFURAN 2 CARBOXAMIDE; 6 METHOXY 3 METHYL N PHENYL N [3 (PIPERIDIN 1 YL)PROPYL]BENZOFURAN 2 CARBOXAMIDE; 6 METHOXY 3 METHYL N PHENYLBENZOFURAN 2 CARBOXAMIDE; AMIDE; HALOGEN; N PHENYL N [3 (PIPERIDIN 1 YL)PROPYL]BENZOFURAN 2 CARBOXAMIDE; OPIATE RECEPTOR; SIGMA RECEPTOR LIGAND; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; BINDING SITE; CHEMICAL REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; HALOGENATION; RECEPTOR AFFINITY;

ANIMALS; BENZOFURANS; CELL LINE; HUMANS; LIGANDS; RADIOLIGAND ASSAY; RECEPTORS, SIGMA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84869094922     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2012.09.044     Document Type: Article

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