Usefulness of cardiac biomarkers in the prediction of right ventricular dysfunction before echocardiography in acute pulmonary embolism

Journal of Cardiology

Volumn 60, Issue 6, 2012, Pages 508-513

  Choi, Hong Sang ^a   Kim, Kye Hun ^a   Yoon, Hyun Ju ^a   Hong, Young Joon ^a   Kim, Ju Han ^a   Ahn, Youngkeun ^a   Jeong, Myung Ho ^a   Cho, Jeong Gwan ^a   Park, Jong Chun ^a   Kang, Jung Chaee ^a  

^a Chonnam National University Medical School   (South Korea)

Author keywords

Biomarker; Pulmonary embolism; Ventricular dysfunction

Indexed keywords

AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; BIOLOGICAL MARKER; C REACTIVE PROTEIN; CREATINE KINASE; CREATINE KINASE MB; TROPONIN T;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; ECHOCARDIOGRAPHY; FEMALE; HEART RIGHT VENTRICLE FAILURE; HUMAN; LUNG EMBOLISM; MAJOR CLINICAL STUDY; MALE; MEASUREMENT; PREDICTIVE VALUE; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SEROLOGY;

ACUTE DISEASE; AGED; BIOLOGICAL MARKERS; ECHOCARDIOGRAPHY; FEMALE; FORECASTING; HUMANS; MALE; MIDDLE AGED; NATRIURETIC PEPTIDE, BRAIN; PEPTIDE FRAGMENTS; PULMONARY EMBOLISM; RETROSPECTIVE STUDIES; TROPONIN; TROPONIN I; TROPONIN T; VENTRICULAR DYSFUNCTION, RIGHT;

EID: 84869091505     PISSN: 09145087     EISSN: 18764738     Source Type: Journal    
DOI: 10.1016/j.jjcc.2012.07.006     Document Type: Article

References (36)

1. Goldhaber S.Z., Visani L., De Rosa M. Acute pulmonary embolism: clinical outcomes in the International Cooperative Pulmonary Embolism Registry (ICOPER). Lancet 1999, 353:1386-1389.
2. Heit J.A., Melton L.J., Lohse C.M., Petterson T.M., Silverstein M.D., Mohr D.N., O'Fallon W.M. Incidence of venous thromboembolism in hospitalized patients vs community residents. Mayo Clin Proc 2001, 76:1102-1110.
3. Kasper W., Konstantinides S., Geibel A., Olschewski M., Heinrich F., Grosser K.D., Rauber K., Iversen S., Redecker M., Kienast J. Management strategies and determinants of outcome in acute major pulmonary embolism: results of a multicenter registry. J Am Coll Cardiol 1997, 30:1165-1171.
4. Buller H.R., Agnelli G., Hull R.D., Hyers T.M., Prins M.H., Raskob G.E. Antithrombotic therapy for venous thromboembolic disease: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest 2004, 126:401S-428S.
5. Torbicki A., Perrier A., Konstantinides S., Agnelli G., Galie N., Pruszczyk P., Bengel F., Brady A.J., Ferreira D., Janssens U., Klepetko W., Mayer E., Remy-Jardin M., Bassand J.P., Vahanian A., et al. Guidelines on the diagnosis and management of acute pulmonary embolism: the Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC). Eur Heart J 2008, 29:2276-2315.
6. Grifoni S., Olivotto I., Cecchini P., Pieralli F., Camaiti A., Santoro G., Conti A., Agnelli G., Berni G. Short-term clinical outcome of patients with acute pulmonary embolism, normal blood pressure, and echocardiographic right ventricular dysfunction. Circulation 2000, 101:2817-2822.
7. Kreit J.W. The impact of right ventricular dysfunction on the prognosis and therapy of normotensive patients with pulmonary embolism. Chest 2004, 125:1539-1545.
8. Kucher N., Rossi E., De Rosa M., Goldhaber S.Z. Prognostic role of echocardiography among patients with acute pulmonary embolism and a systolic arterial pressure of 90mmHg or higher. Arch Intern Med 2005, 165:1777-1781.
9. Ribeiro A., Lindmarker P., Juhlin-Dannfelt A., Johnsson H., Jorfeldt L. Echocardiography Doppler in pulmonary embolism: right ventricular dysfunction as a predictor of mortality rate. Am Heart J 1997, 134:479-487.
10. Sanchez O., Trinquart L., Colombet I., Durieux P., Huisman M.V., Chatellier G., Meyer G. Prognostic value of right ventricular dysfunction in patients with haemodynamically stable pulmonary embolism: a systematic review. Eur Heart J 2008, 29:1569-1577.
11. Goldhaber S.Z. Echocardiography in the management of pulmonary embolism. Ann Intern Med 2002, 136:691-700.
12. Sato Y., Nishi K., Taniguchi R., Miyamoto T., Fukuhara R., Yamane K., Saijyo S., Tanada Y., Yamamoto E., Goto T., Takahashi N., Fujiwara H., Takatsu Y. In patients with heart failure and non-ischemic heart disease, cardiac troponin T is a reliable predictor of long-term echocardiographic changes and adverse cardiac events. J Cardiol 2009, 54:221-230.
13. Nishikimi T., Kuwahara K., Nakao K. Current biochemistry, molecular biology, and clinical relevance of natriuretic peptides. J Cardiol 2011, 57:131-140.
14. Kline J.A., Hernandez-Nino J., Rose G.A., Norton H.J., Camargo C.A. Surrogate markers for adverse outcomes in normotensive patients with pulmonary embolism. Crit Care Med 2006, 34:2773-2780.
15. Kucher N., Goldhaber S.Z. Cardiac biomarkers for risk stratification of patients with acute pulmonary embolism. Circulation 2003, 108:2191-2194.
16. Mikulewicz M., Lewczuk J. Importance of cardiac biomarkers in risk stratification in acute pulmonary embolism. Cardiol J 2008, 15:17-20.
17. Ten Wolde M., Tulevski I.I., Mulder J.W., Sohne M., Boomsma F., Mulder B.J., Buller H.R. Brain natriuretic peptide as a predictor of adverse outcome in patients with pulmonary embolism. Circulation 2003, 107:2082-2084.
18. Tulevski I.I., Ten Wolde M., van Veldhuisen D.J., Mulder J.W., van der Wall E.E., Buller H.R., Mulder B.J. Combined utility of brain natriuretic peptide and cardiac troponin T may improve rapid triage and risk stratification in normotensive patients with pulmonary embolism. Int J Cardiol 2007, 116:161-166.
19. Krüger S., Graf J., Merx M.W., Koch K.C., Kunz D., Hanrath P., Janssens U. Brain natriuretic peptide predicts right heart failure in patients with acute pulmonary embolism. Am Heart J 2004, 147:60-65.
20. Logeart D., Lecuyer L., Thabut G., Tabet J.Y., Tartiere J.M., Chavelas C., Bonnin F., Stievenart J.L., Solal A.C. Biomarker-based strategy for screening right ventricular dysfunction in patients with non-massive pulmonary embolism. Intensive Care Med 2007, 33:286-292.
21. Meyer T., Binder L., Hruska N., Luthe H., Buchwald A.B. Cardiac troponin I elevation in acute pulmonary embolism is associated with right ventricular dysfunction. J Am Coll Cardiol 2000, 36:1632-1636.
22. Yardan T., Altintop L., Baydin A., Yilmaz O., Guven H. B-type natriuretic peptide as an indicator of right ventricular dysfunction in acute pulmonary embolism. Int J Clin Pract 2008, 62:1177-1182.
23. Pieralli F., Olivotto I., Vanni S., Conti A., Camaiti A., Targioni G., Grifoni S., Berni G. Usefulness of bedside testing for brain natriuretic peptide to identify right ventricular dysfunction and outcome in normotensive patients with acute pulmonary embolism. Am J Cardiol 2006, 97:1386-1390.
24. Lega J.C., Lacasse Y., Lakhal L., Provencher S. Natriuretic peptides and troponins in pulmonary embolism: a meta-analysis. Thorax 2009, 64:869-875.
25. Lang R.M., Bierig M., Devereux R.B., Flachskampf F.A., Foster E., Pellikka P.A., Picard M.H., Roman M.J., Seward J., Shanewise J.S., Solomon S.D., Spencer K.T., Sutton M.S., Stewart W.J., Chamber Quantification Writing Group, et al. Recommendations for chamber quantification: a report from the American Society of Echocardiography's Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J Am Soc Echocardiogr 2005, 18:1440-1463.
26. Konstantinides S., Geibel A., Olschewski M., Kasper W., Hruska N., Jäckle S., Binder L. Importance of cardiac troponins I and T in risk stratification of patients with acute pulmonary embolism. Circulation 2002, 106:1263-1267.
27. Amorim S., Dias P., Rodrigues R.A., Araújo V., Macedo F., Maciel M.J., Gonçalves F.R. Troponin I as a marker of right ventricular dysfunction and severity of pulmonary embolism. Rev Port Cardiol 2006, 25:181-186.
28. Margato R., Carvalho S., Ribeiro H., Mateus P., Fontes P., Moreira J.I. Cardiac troponin I levels in acute pulmonary embolism. Rev Port Cardiol 2009, 28:1213-1222.
29. Januzzi J.L., Bamberg F., Lee H., Truong Q.A., Nichols J.H., Karakas M., Mohammed A.A., Schlett C.L., Nagurney J.T., Hoffmann U., Koenig W. High-sensitivity troponin T concentrations in acute chest pain patients evaluated with cardiac computed tomography. Circulation 2010, 121:1227-1234.
30. Sato Y., Yamamoto E., Sawa T., Toda K., Hara T., Iwasaki T., Fujiwara H., Takatsu Y. High-sensitivity cardiac troponin T in essential hypertension. J Cardiol 2011, 58:226-231.
31. Kusumoto A., Miyata M., Kubozono T., Ikeda Y., Shinsato T., Kuwahata S., Fujita S., Takasaki K., Yuasa T., Hamasaki S., Tei C. Highly sensitive cardiac troponin T in heart failure: comparison with echocardiographic parameters and natriuretic peptides. J Cardiol 2012, 59:202-208.
32. Lagrand W.K., Visser C.A., Hermens W.T., Niessen H.W., Verheugt F.W., Wolbink G.J., Hack C.E. C-reactive protein as a cardiovascular risk factor: more than an epiphenomenon?. Circulation 1999, 100:96-102.
33. Ridker P.M., Rifai N., Rose L., Buring J.E., Cook N.R. Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. N Engl J Med 2002, 347:1557-1565.
34. Abul Y., Karakurt S., Ozben B., Toprak A. C-reactive protein in acute pulmonary embolism. J Investig Med 2011, 59:8-14.
35. Adams J.E., Siegel B.A., Goldstein J.A., Jaffe A.S. Elevations of CK-MB following pulmonary embolism. A manifestation of occult right ventricular infarction. Chest 1992, 101:1203-1206.
36. Stein P.D., Janjua M., Matta F., Pathak P.K., Jaweesh F., Alrifai A., Chughtai H.L., Stein P.D., Janjua M., Matta F., Pathak P.K., Jaweesh F., Alrifai A., Chughtai H.L. Prognosis based on creatine kinase isoenzyme MB, cardiac troponin I, and right ventricular size in stable patients with acute pulmonary embolism. Am J Cardiol 2011, 107:774-777.