Improvement of Left Ventricular Function under Cardiac Resynchronization Therapy Goes along with a Reduced Incidence of Ventricular Arrhythmia

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Eickholt, Christian ^a   Siekiera, Marcus ^a   Kirmanoglou, Kiriakos ^a   Rodenbeck, Astrid ^b   Heussen, Nicole ^b   Schauerte, Patrick ^b   Lichtenberg, Artur ^c   Balzer, Jan ^a   Rassaf, Tienush ^a   Perings, Stefan ^a   Kelm, Malte ^a   Shin, Dong In ^a   Meyer, Christian ^a  

^a Department of Orthopedic Surgery   (Germany)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^c HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMIODARONE; ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIGITALIS; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOOP DIURETIC AGENT; SPIRONOLACTONE;

ADULT; ARTICLE; CARDIAC RESYNCHRONIZATION THERAPY; CONTROLLED STUDY; DEFIBRILLATION; DISEASE SEVERITY; FEMALE; FOLLOW UP; HEART FAILURE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE FUNCTION; HEART VENTRICLE ARRHYTHMIA; HUMAN; IMPLANTABLE CARDIOVERTER DEFIBRILLATOR; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; QRS COMPLEX; RECEIVER OPERATING CHARACTERISTIC; REFERENCE VALUE; SECONDARY PREVENTION; TREATMENT RESPONSE;

AGED; ARRHYTHMIAS, CARDIAC; CARDIAC RESYNCHRONIZATION THERAPY; FEMALE; FOLLOW-UP STUDIES; HEART FAILURE; HUMANS; INCIDENCE; MALE; MIDDLE AGED; ROC CURVE; STROKE VOLUME; TREATMENT OUTCOME; VENTRICULAR FUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 84869025744     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0048926     Document Type: Article

References (46)

1. Linde C, Ellenbogen K, McAlister FA, (2012) Cardiac resynchronization therapy (CRT): Clinical trials, guidelines, and target populations. Heart Rhythm 9: S3-S13.
2. Barsheshet A, Wang PJ, Moss AJ, Solomon SD, Al-Ahmad A, et al. (2011) Reverse remodeling and the risk of ventricular tachyarrhythmias in the MADIT-CRT (Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy). J Am Coll Cardiol 57: 2416-2423.
3. Di Biase L, Gasparini M, Lunati M, Santini M, Landolina M, et al. (2008) Antiarrhythmic effect of reverse ventricular remodeling induced by cardiac resynchronization therapy: the InSync ICD (Implantable Cardioverter-Defibrillator) Italian Registry. J Am Coll Cardiol 52: 1442-1449.
4. Arya A, Haghjoo M, Dehghani MR, Alasti M, Alizadeh H, et al. (2005) Effect of cardiac resynchronization therapy on the incidence of ventricular arrhythmias in patients with an implantable cardioverter-defibrillator. Heart Rhythm 2: 1094-1098.
5. Kurita T, Noda T, Aiba T, Nakajima I, Shimizu W, et al. (2011) Cardiac resynchronization therapy to prevent life-threatening arrhythmias in patients with congestive heart failure. J Electrocardiol 44: 736-741.
6. Fish JM, Brugada J, Antzelevitch C, (2005) Potential proarrhythmic effects of biventricular pacing. J Am Coll Cardiol 46: 2340-2347.
7. Guerra JM, Wu J, Miller JM, Groh WJ, (2003) Increase in ventricular tachycardia frequency after biventricular implantable cardioverter defibrillator upgrade. J Cardiovasc Electrophysiol 14: 1245-1247.
8. Bradley DJ, Bradley EA, Baughman KL, Berger RD, Calkins H, et al. (2003) Cardiac resynchronization and death from progressive heart failure: a meta-analysis of randomized controlled trials. JAMA 289: 730-740.
9. Singh JP, Gras D, (2012) Biventricular pacing: current trends and future strategies. Eur Heart J 33: 305-313.
10. St John Sutton M, Ghio S, Plappert T, Tavazzi L, Scelsi L, et al. (2009) Cardiac resynchronization induces major structural and functional reverse remodeling in patients with New York Heart Association class I/II heart failure. Circulation 120: 1858-1865.
11. Ukkonen H, Sundell J, Knuuti J, (2008) Effects of CRT on myocardial innervation, perfusion and metabolism. Europace 10 (Suppl 3):: iii114-iii117.
12. Sachse FB, Torres NS, Savio-Galimberti E, Aiba T, Kass DA, et al. (2012) Subcellular structures and function of myocytes impaired during heart failure are restored by cardiac resynchronization therapy. Circ Res 110: 588-597.
13. Kass DA, (2009) Pathobiology of cardiac dyssynchrony and resynchronization. Heart Rhythm 6: 1660-1665.
14. Aiba T, Tomaselli G, (2012) Electrical remodeling in dyssynchrony and resynchronization. J Cardiovasc Transl Res 5: 170-179.
15. Chakir K, Daya SK, Aiba T, Tunin RS, Dimaano VL, et al. (2009) Mechanisms of enhanced beta-adrenergic reserve from cardiac resynchronization therapy. Circulation 119: 1231-1240.
16. Knappe D, Pouleur AC, Shah AM, Cheng S, Uno H, et al. (2011) Dyssynchrony, contractile function, and response to cardiac resynchronization therapy. Circ Heart Fail 4: 433-440.
17. Chan CP, Zhang Q, Yip GW, Fung JW, Lam YY, et al. (2008) Relation of left ventricular systolic dyssynchrony in patients with heart failure to left ventricular ejection fraction and to QRS duration. Am J Cardiol 102: 602-605.
18. Butter C, Wellnhofer E, Seifert M, Schlegl M, Hoersch W, et al. (2006) Time course of left ventricular volumes in severe congestive heart failure patients treated by optimized AV sequential left ventricular pacing alone-a 3-dimensional echocardiographic study. Am Heart J 151: 115-123.
19. Penicka M, Bartunek J, De Bruyne B, Vanderheyden M, Goethals M, et al. (2004) Improvement of left ventricular function after cardiac resynchronization therapy is predicted by tissue Doppler imaging echocardiography. Circulation 109: 978-983.
20. Ypenburg C, van Erven L, Bleeker GB, Bax JJ, Bootsma M, et al. (2006) Benefit of combined resynchronization and defibrillator therapy in heart failure patients with and without ventricular arrhythmias. J Am Coll Cardiol 48: 464-470.
21. Daubert JC, Saxon L, Adamson PB, Auricchio A, Berger RD, et al. (2012) 2012 EHRA/HRS expert consensus statement on cardiac resynchronization therapy in heart failure: implant and follow-up recommendations and management. Heart Rhythm 9: 1524-1576.
22. McMurray JJ, Adamopoulos S, Anker SD, Auricchio A, Böhm M, et al. (2012) ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur Heart J 33: 1787-1847.
23. León AR, Delurgio DB, Mera F, (2005) Practical approach to implanting left ventricular pacing leads for cardiac resynchronization. J Cardiovasc Electrophysiol 16: 100-105.
24. Bax JJ, Abraham T, Barold SS, Breithardt OA, Fung JW, et al. (2005) Cardiac resynchronization therapy: Part 2-issues during and after device implantation and unresolved questions. J Am Coll Cardiol 46: 2168-2182.
25. Gehi AK, Mehta D, Gomes JA, (2006) Evaluation and management of patients after implantable cardioverter-defibrillator shock. JAMA 296: 2839-2847.
26. Koneru JN, Swerdlow CD, Wood MA, Ellenbogen KA, (2011) Minimizing inappropriate or "unnecessary" implantable cardioverter-defibrillator shocks: appropriate programming. Circ Arrhythm Electrophysiol 4: 778-790.
27. Meyer C, Schueller P, Rodenbeck A, Hennersdorf M, Merx M, et al. (2009) Primary and secondary prevention of ventricular arrhythmias in dilated cardiomyopathy: nonsustained, sustained, and incessant. Int Heart J 50: 741-751.
28. Lang RM, Bierig M, Devereux RB, Flachskampf FA, Foster E, et al. (2005) Recommendations for chamber quantification: a report from the American Society of Echocardiography's Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J Am Soc Echocardiogr 18: 1440-1463.
29. Pouleur AC, Knappe D, Shah AM, Uno H, Bourgoun M, et al. (2011) Relationship between improvement in left ventricular dyssynchrony and contractile function and clinical outcome with cardiac resynchronization therapy: the MADIT-CRT trial. Eur Heart J 32: 1720-1729.
30. Steffel J, Milosevic G, Hürlimann A, Krasniqi N, Namdar M, et al. (2011) Characteristics and long-term outcome of echocardiographic super-responders to cardiac resynchronisation therapy: 'real world' experience from a single tertiary care centre. Heart 97: 1668-1674.
31. Kiès P, Bax JJ, Molhoek SG, Bleeker GB, Zeppenfeld K, et al. (2005) Effect of cardiac resynchronization therapy on inducibility of ventricular tachyarrhythmias in cardiac arrest survivors with either ischemic or idiopathic dilated cardiomyopathy. Am J Cardiol 95: 1111-1114.
32. Aiba T, Tomaselli GF, (2010) Electrical remodeling in the failing heart. Curr Opin Cardiol 25: 29-36.
33. Higgins SL, Yong P, Sheck D, McDaniel M, Bollinger F, et al. (2000) Biventricular pacing diminishes the need for implantable cardioverter defibrillator therapy. Ventak CHF Investigators. J Am Coll Cardiol 36: 824-827.
34. Anand IS, Carson P, Galle E, Song R, Boehmer J, et al. (2009) Cardiac resynchronization therapy reduces the risk of hospitalizations in patients with advanced heart failure: results from the Comparison of Medical Therapy, Pacing and Defibrillation in Heart Failure (COMPANION) trial. Circulation 119: 969-977.
35. Lellouche N, De Diego C, Boyle NG, Wiener I, Akopyan G, et al. (2011) Relationship between mechanical and electrical remodelling in patients with cardiac resynchronization implanted defibrillators. Europace 13: 1180-1187.
36. Di Cori A, Bongiorni MG, Arena G, Soldati E, Giannola G, et al. (2005) New-onset ventricular tachycardia after cardiac resynchronization therapy. J Interv Card Electrophysiol 12: 231-235.
37. Cleland JG, Daubert JC, Erdmann E, Freemantle N, Gras D, et al. (2006) Longer-term effects of cardiac resynchronization therapy on mortality in heart failure [the CArdiac REsynchronization-Heart Failure (CARE-HF) trial extension phase]. Eur Heart J 27: 1928-1932.
38. Lin G, Rea RF, Hammill SC, Hayes DL, Brady PA, (2008) Effect of cardiac resynchronisation therapy on occurrence of ventricular arrhythmia in patients with implantable cardioverter defibrillators undergoing upgrade to cardiac resynchronisation therapy devices. Heart 94: 186-190.
39. Kronborg MB, Nielsen JC, Mortensen PT, (2010) Electrocardiographic patterns and long-term clinical outcome in cardiac resynchronization therapy. Europace 12: 216-222.
40. Boriani G, Biffi M, Martignani C, Ziacchi M, Saporito D, et al. (2006) Electrocardiographic remodeling during cardiac resynchronization therapy. Int J Cardiol 108: 165-170.
41. Boriani G, Diemberger I, Valzania C, Biffi M, Martignani C, et al. (2010) Role of drugs and devices in patients at risk of sudden cardiac death. Fundam Clin Pharmacol 24: 575-594.
42. Jenkins C, Moir S, Chan J, Rakhit D, Haluska B, et al. (2009) Left ventricular volume measurement with echocardiography: a comparison of left ventricular opacification, three-dimensional echocardiography, or both with magnetic resonance imaging. Eur Heart J 30: 98-106.
43. Metra M, Ponikowski P, Dickstein K, McMurray JJ, Gavazzi A, et al. (2007) Advanced chronic heart failure: A position statement from the Study Group on Advanced Heart Failure of the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail 9: 684-694.
44. Linde C, Leclercq C, Rex S, Garrigue S, Lavergne T, et al. (2002) Long-term benefits of biventricular pacing in congestive heart failure: results from the MUltisite STimulation in cardiomyopathy (MUSTIC) study. J Am Coll Cardiol 40: 111-118.
45. Higgins SL, Hummel JD, Niazi IK, Giudici MC, Worley SJ, et al. (2003) Cardiac resynchronization therapy for the treatment of heart failure in patients with intraventricular conduction delay and malignant ventricular tachyarrhythmias. J Am Coll Cardiol 42: 1454-1459.
46. Ypenburg C, van Bommel RJ, Borleffs CJ, Bleeker GB, Boersma E, et al. (2009) Long-term prognosis after cardiac resynchronization therapy is related to the extent of left ventricular reverse remodeling at midterm follow-up. J Am Coll Cardiol 53: 483-490.