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Volumn 53, Issue 12, 2012, Pages 2716-2725

STARD4 knockdown in HepG2 cells disrupts cholesterol trafficking associated with the plasma membrane, ER, and ERC

Author keywords

Cholesterol; Endocytic recycling compartment; Endoplasmic reticulum; Hepatocellular carcinoma; Intracellular cholesterol transport; Low density lipoprotein receptor; StAR related lipid transfer domain protein

Indexed keywords

ACETYL COENZYME A ACETYLTRANSFERASE; CHOLESTEROL; CHOLESTEROL ESTER; LIPID TRANSFER PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; MEMBRANE PROTEIN; NIEMANN PICK TYPE C1 PROTEIN; SHORT HAIRPIN RNA; STEROIDOGENIC ACUTE REGULATORY RELATED LIPID TRANSFER DOMAIN PROTEIN 4; UNCLASSIFIED DRUG;

EID: 84869022042     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M032227     Document Type: Article
Times cited : (33)

References (33)
  • 1
    • 0033583562 scopus 로고    scopus 로고
    • Intracellular cholesterol transport
    • Liscum, L., and N. Munn. 1999. Intracellular cholesterol transport. Biochim. Biophys. Acta. 1438: 19-37.
    • (1999) Biochim. Biophys. Acta , vol.1438 , pp. 19-37
    • Liscum, L.1    Munn, N.2
  • 2
    • 0023655537 scopus 로고
    • Subcellular localization of the enzymes of cholesterol biosynthesis and metabolism in rat liver
    • Reinhart, M. P., J. T. Billheimer, J. R. Faust, and J. L. Gaylor. 1987. Subcellular localization of the enzymes of cholesterol biosynthesis and metabolism in rat liver. J. Biol. Chem. 262: 9649-9655.
    • (1987) J. Biol. Chem. , vol.262 , pp. 9649-9655
    • Reinhart, M.P.1    Billheimer, J.T.2    Faust, J.R.3    Gaylor, J.L.4
  • 3
    • 0034681939 scopus 로고    scopus 로고
    • Efflux of cholesterol from different cellular pools
    • Haynes, M. P., M. Phillips, and G. Rothblat. 2000. Efflux of cholesterol from different cellular pools. Biochemistry. 39: 4508-4517.
    • (2000) Biochemistry , vol.39 , pp. 4508-4517
    • Haynes, M.P.1    Phillips, M.2    Rothblat, G.3
  • 5
    • 0029972116 scopus 로고    scopus 로고
    • The distal pathway of lipoprotein-induced cholesterol esterification, but not sphingomyelinase-induced cholesterol esterification, is energy-dependent
    • Skiba, P. J., X. Zha, F. Maxfield, S. Schissel, and I. Tabas. 1996. The distal pathway of lipoprotein-induced cholesterol esterification, but not sphingomyelinase-induced cholesterol esterification, is energy-dependent. J. Biol. Chem. 271: 13392-13400.
    • (1996) J. Biol. Chem. , vol.271 , pp. 13392-13400
    • Skiba, P.J.1    Zha, X.2    Maxfield, F.3    Schissel, S.4    Tabas, I.5
  • 6
    • 77952311395 scopus 로고    scopus 로고
    • Mammalian StAR-related lipid transfer (START) domains with specificity for cholesterol: Structural conservation and mechanism of reversible binding
    • Lavigne, P., R. Najmanivich, and J. G. Lehoux. 2010. Mammalian StAR-related lipid transfer (START) domains with specificity for cholesterol: structural conservation and mechanism of reversible binding. Subcell. Biochem. 51: 425-437.
    • (2010) Subcell. Biochem. , vol.51 , pp. 425-437
    • Lavigne, P.1    Najmanivich, R.2    Lehoux, J.G.3
  • 7
    • 0037591389 scopus 로고    scopus 로고
    • StAR-related Lipid Transfer (START) proteins: Mediators of intracellular lipid metabolism
    • Soccio, R. E. 2003. StAR-related Lipid Transfer (START) proteins: mediators of intracellular lipid metabolism. J. Biol. Chem. 278: 22183-22186.
    • (2003) J. Biol. Chem. , vol.278 , pp. 22183-22186
    • Soccio, R.E.1
  • 8
    • 34249787877 scopus 로고    scopus 로고
    • Steroidogenic acute regulatory protein (StAR), a novel mitochondrial cholesterol transporter
    • Miller, W. 2007. Steroidogenic acute regulatory protein (StAR), a novel mitochondrial cholesterol transporter. Biochim. Biophys. Acta. 1771: 663-676.
    • (2007) Biochim. Biophys. Acta. , vol.1771 , pp. 663-676
    • Miller, W.1
  • 9
    • 33745759439 scopus 로고    scopus 로고
    • Intracellular sterol transport and distribution
    • Maxfield, F. R., and A. K. Menon. 2006. Intracellular sterol transport and distribution. Curr. Opin. Cell Biol. 18: 379-385.
    • (2006) Curr. Opin. Cell Biol. , vol.18 , pp. 379-385
    • Maxfield, F.R.1    Menon, A.K.2
  • 10
    • 34848880480 scopus 로고    scopus 로고
    • Non-vesicular sterol transport in cells
    • Prinz, W. A. 2007. Non-vesicular sterol transport in cells. Prog. Lipid Res. 46: 297-314.
    • (2007) Prog. Lipid Res. , vol.46 , pp. 297-314
    • Prinz, W.A.1
  • 11
    • 0038630960 scopus 로고    scopus 로고
    • START domain proteins and the intracellular trafficking of cholesterol in steroidogenic cells
    • Strauss, J. F, T. Kishida, L. Christenson, T. Fujimoto, and H. Hiroi. 2003. START domain proteins and the intracellular trafficking of cholesterol in steroidogenic cells. Mol. Cell. Endocrinol. 202: 59-65.
    • (2003) Mol. Cell. Endocrinol. , vol.202 , pp. 59-65
    • Strauss, J.F.1    Kishida, T.2    Christenson, L.3    Fujimoto, T.4    Hiroi, H.5
  • 12
    • 23744478870 scopus 로고    scopus 로고
    • Give lipids a START: The StAR-related lipid transfer (START) domain in mammals
    • Alpy, F. 2005. Give lipids a START: the StAR-related lipid transfer (START) domain in mammals. J. Cell Sci. 118: 2791-2801.
    • (2005) J. Cell Sci. , vol.118 , pp. 2791-2801
    • Alpy, F.1
  • 14
    • 50949123980 scopus 로고    scopus 로고
    • Intracellular cholesterol transporter StarD4 binds free cholesterol and increases cholesteryl ester formation
    • Rodriguez-Agudo, D., S. Ren, E. Wong, D. Marques, K. Redford, G. Gil, P. Hylemon, and W. M. Pandak. 2008. Intracellular cholesterol transporter StarD4 binds free cholesterol and increases cholesteryl ester formation. J. Lipid Res. 49: 1409-1419.
    • (2008) J. Lipid Res. , vol.49 , pp. 1409-1419
    • Rodriguez-Agudo, D.1    Ren, S.2    Wong, E.3    Marques, D.4    Redford, K.5    Gil, G.6    Hylemon, P.7    Pandak, W.M.8
  • 15
    • 0037076275 scopus 로고    scopus 로고
    • The cholesterol-regulated StarD4 gene encodes a StAR-related lipid transfer protein with two closely related homologues, StarD5 and StarD6
    • Soccio, R. E., R. Adams, M. Romanowski, E. Sehayek, S. Burley, and J. Breslow. 2002. The cholesterol-regulated StarD4 gene encodes a StAR-related lipid transfer protein with two closely related homologues, StarD5 and StarD6. Proc. Natl. Acad. Sci. USA. 99: 6943-6948.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 6943-6948
    • Soccio, R.E.1    Adams, R.2    Romanowski, M.3    Sehayek, E.4    Burley, S.5    Breslow, J.6
  • 16
    • 0037076327 scopus 로고    scopus 로고
    • Crystal structure of the Mus musculus cholesterol-regulated START protein 4 (StarD4) containing a StAR-related lipid transfer domain
    • Romanowski, M. J., R. Soccio, J. Breslow, and S. Burley. 2002. Crystal structure of the Mus musculus cholesterol-regulated START protein 4 (StarD4) containing a StAR-related lipid transfer domain. Proc. Natl. Acad. Sci. USA. 99: 6949-6954.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 6949-6954
    • Romanowski, M.J.1    Soccio, R.2    Breslow, J.3    Burley, S.4
  • 19
    • 0021352317 scopus 로고
    • Histochemical detection of esterified cholesterol within human atherosclerotic lesions using the fluorescent probe filipin
    • Kruth, H. S. 1984. Histochemical detection of esterified cholesterol within human atherosclerotic lesions using the fluorescent probe filipin. Atherosclerosis. 51: 281-292.
    • (1984) Atherosclerosis , vol.51 , pp. 281-292
    • Kruth, H.S.1
  • 20
    • 0020197884 scopus 로고
    • Lateral mobility in membranes as detected by fluorescence recovery after photobleaching
    • Yguerabide, J., J. A. Schmidt, and E. E. Yguerabide. 1982. Lateral mobility in membranes as detected by fluorescence recovery after photobleaching. Biophys. J. 40: 69-75.
    • (1982) Biophys. J. , vol.40 , pp. 69-75
    • Yguerabide, J.1    Schmidt, J.A.2    Yguerabide, E.E.3
  • 22
    • 21444455252 scopus 로고    scopus 로고
    • Differential gene regulation of StarD4 and StarD5 cholesterol transfer proteins. Activation of StarD4 by sterol regulatory element-binding protein-2 and StarD5 by endoplasmic reticulum stress
    • Soccio, R. E., R. Adams, K. Maxwell, and J. Breslow. 2005. Differential gene regulation of StarD4 and StarD5 cholesterol transfer proteins. Activation of StarD4 by sterol regulatory element-binding protein-2 and StarD5 by endoplasmic reticulum stress. J. Biol. Chem. 280: 19410-19418.
    • (2005) J. Biol. Chem. , vol.280 , pp. 19410-19418
    • Soccio, R.E.1    Adams, R.2    Maxwell, K.3    Breslow, J.4
  • 23
    • 0015890890 scopus 로고
    • Familial hypercholesterolemia: Identification of a defect in the regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity associated with overproduction of cholesterol
    • Goldstein, J. L., and M. S. Brown. 1973. Familial hypercholesterolemia: identification of a defect in the regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity associated with overproduction of cholesterol. Proc. Natl. Acad. Sci. USA. 70: 2804-2808.
    • (1973) Proc. Natl. Acad. Sci. USA , vol.70 , pp. 2804-2808
    • Goldstein, J.L.1    Brown, M.S.2
  • 24
    • 0015989544 scopus 로고
    • Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured human fibroblasts. Comparison of cells from a normal subject and from a patient with homozygous familial hypercholesterolemia
    • Brown, M. S., S. E. Dana, and J. L. Goldstein. 1974. Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured human fibroblasts. Comparison of cells from a normal subject and from a patient with homozygous familial hypercholesterolemia. J. Biol. Chem. 249: 789-796.
    • (1974) J. Biol. Chem. , vol.249 , pp. 789-796
    • Brown, M.S.1    Dana, S.E.2    Goldstein, J.L.3
  • 25
    • 84934434313 scopus 로고    scopus 로고
    • Fractionation of subcellular membrane vesicles of epithelial and nonepithelial cells by OptiPrep density gradient ultracentrifugation
    • Li, X., and M. Donowitz. 2008. Fractionation of subcellular membrane vesicles of epithelial and nonepithelial cells by OptiPrep density gradient ultracentrifugation. Methods Mol. Biol. 440: 97-110.
    • (2008) Methods Mol. Biol. , vol.440 , pp. 97-110
    • Li, X.1    Donowitz, M.2
  • 26
    • 0031687965 scopus 로고    scopus 로고
    • Cholesterol distribution in living cells: Fluorescence imaging using dehydroergosterol as a fluorescent cholesterol analog
    • Mukherjee, S., X. Zha, I. Tabas, and F. Maxfield. 1998. Cholesterol distribution in living cells: fluorescence imaging using dehydroergosterol as a fluorescent cholesterol analog. Biophys. J. 75: 1915-1925.
    • (1998) Biophys. J. , vol.75 , pp. 1915-1925
    • Mukherjee, S.1    Zha, X.2    Tabas, I.3    Maxfield, F.4
  • 28
    • 33846867956 scopus 로고    scopus 로고
    • Fluorescent sterols as tools in membrane biophysics and cell biology
    • Wustner, D. 2007. Fluorescent sterols as tools in membrane biophysics and cell biology. Chem. Phys. Lipids. 146: 1-25.
    • (2007) Chem. Phys. Lipids , vol.146 , pp. 1-25
    • Wustner, D.1
  • 29
    • 0037016677 scopus 로고    scopus 로고
    • Vesicular and non-vesicular sterol transport in living cells. The endocytic recycling compartment is a major sterol storage organelle
    • Hao, M., S. Lin, O. Karylowski, D. Wustner, T. McGraw, and F. Maxfield. 2002. Vesicular and non-vesicular sterol transport in living cells. The endocytic recycling compartment is a major sterol storage organelle. J. Biol. Chem. 277: 609-617.
    • (2002) J. Biol. Chem. , vol.277 , pp. 609-617
    • Hao, M.1    Lin, S.2    Karylowski, O.3    Wustner, D.4    McGraw, T.5    Maxfield, F.6
  • 30
    • 61949446361 scopus 로고    scopus 로고
    • Sterols are mainly in the cytoplasmic leaflet of the plasma membrane and the endocytic recycling compartment in CHO cells
    • Mondal, M., B. Mesmin, S. Mukherjee, and F. R. Maxfield. 2009. Sterols are mainly in the cytoplasmic leaflet of the plasma membrane and the endocytic recycling compartment in CHO cells. Mol. Biol. Cell. 20: 581-588.
    • (2009) Mol. Biol. Cell. , vol.20 , pp. 581-588
    • Mondal, M.1    Mesmin, B.2    Mukherjee, S.3    Maxfield, F.R.4
  • 31
    • 0037119406 scopus 로고    scopus 로고
    • Rapid nonvesicular transport of sterol between the plasma membrane domains of polarized hepatic cells
    • Wustner, D., A. Herrmann, M. Hao, and F. Maxfield. 2002. Rapid nonvesicular transport of sterol between the plasma membrane domains of polarized hepatic cells. J. Biol. Chem. 277: 30325-30336.
    • (2002) J. Biol. Chem. , vol.277 , pp. 30325-30336
    • Wustner, D.1    Herrmann, A.2    Hao, M.3    Maxfield, F.4
  • 32
    • 77951088614 scopus 로고    scopus 로고
    • Targeted disruption of StARD4 leads to modest weight reduction and minor alterations in lipid metabolism
    • Riegelhaupt, J. J., M. P. Waase, J. Garbarino, D. E. Cruz, and J. L. Breslow. 2010. Targeted disruption of StARD4 leads to modest weight reduction and minor alterations in lipid metabolism. J. Lipid Res. 51: 1134-1143.
    • (2010) J. Lipid Res. , vol.51 , pp. 1134-1143
    • Riegelhaupt, J.J.1    Waase, M.P.2    Garbarino, J.3    Cruz, D.E.4    Breslow, J.L.5
  • 33
    • 23244444808 scopus 로고    scopus 로고
    • Niemann-Pick C1 expression is not regulated by the amount of cholesterol flowing through cells in the mouse
    • Garver, W. S., C. Xie, J. J. Repa, S. D. Turley, and J. M. Dietschy. 2005. Niemann-Pick C1 expression is not regulated by the amount of cholesterol flowing through cells in the mouse. J. Lipid Res. 46: 1745-1754.
    • (2005) J. Lipid Res. , vol.46 , pp. 1745-1754
    • Garver, W.S.1    Xie, C.2    Repa, J.J.3    Turley, S.D.4    Dietschy, J.M.5


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