Evidence required for causal inferences about effects of micronutrient deficiencies during development on brain health: DHA, Choline, Iron, and Vitamin D

Micronutrients and Brain Health

Volumn , Issue , 2009, Pages 355-363

  McCann, Joyce C ^a   Ames, Bruce N ^a  

^a CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84869003052     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (18)

1. McCann, J. C., and Ames, B. N., Is docosahexaenoic acid, an n-3 long chain polyunsaturated fatty acid, required for the development of normal brain function? An overview of evidence from cognitive and behavioral tests in humans and animals. Am J Clin Nutr 82, 281, 2005.
2. McCann, J. C., and Ames, B. N., An overview of evidence for a causal relation between iron deficiency during development and deficits in cognitive or behavioral function. Am J Clin Nutr 85, 931, 2007.
3. McCann, J. C., and Ames, B. N., Is there convincing biological or behavioral evidence linking vitamin D deficiency to brain dysfunction? FASEB J 22, 982, 2008.
4. McCann, J. C., Hudes, M., and Ames, B. N., An overview of evidence for a causal relationship between dietary availability of choline during development and cognitive function in offspring. Neurosci Biobehav Rev 30, 696, 2006.
5. Ames, B. N., Increasing longevity by tuning-up metabolism. EMBO Reports 6, S20, 2005.
6. Ames, B. N., Low micronutrient intake may accelerate the degenerative diseases of aging through allocation of scarce micronutrients by triage. PNAS 103, 17589, 2006.
7. Ames, B. N., Atamna, H., and Killilea, D. W., Mineral and vitamin deficiencies can accelerate the mitochondrial decay of aging. Mol Aspects Med 26, 363, 2005.
8. Ames, B. N., et al., Evidence-based decision making on micronutrients and chronic disease: Long-term randomized controlled trials are not enough. Am J Clin Nutr 86, 522, 2007.
9. Wilkins, C. H., et al., Vitamin D deficiency is associated with low mood and worse cognitive performance in older adults. Am J Geriatr Psychiatry 14, 1032, 2006.
10. Wang, T. T., et al., Large-scale in silico and microarray-based identification of direct 1,25-dihydroxyvitamin D3 target genes. Mol Endocrinol 19, 2685, 2005.
11. Eyles, D., et al., Developmental vitamin D deficiency alters the expression of genes encoding mitochondrial, cytoskeletal and synaptic proteins in the adult rat brain. J Steroid Biochem Mol Biol 2007.
12. McCann, J., and Ames, B. N., DHA and cognitive development: An update on the science. Pediatric Basics 117, 17, 2007.
13. McCann, J. C., and Ames, B. N., Reply to P. Wainwright (Scientific precision and deciding whether to add LCPUFAS to infant formula). Am J Clin Nutr 83, 920, 2006a.
14. Greiner, R. S., et al., Docosapentaenoic acid does not completely replace DHA in n-3 FA-deficient rats during early development. Lipids 38, 431, 2003.
15. Sarkadi-Nagy, E., et al., The influence of prematurity and long chain polyunsaturate supplementation in 4-week adjusted age baboon neonate brain and related tissues. Pediatr Res 54, 244, 2003.
16. Sanders, L. M., and Zeisel, S. H., Choline: Dietary requirements and role in brain development. Nutr Today 42, 181, 2007.
17. Lozoff, B., et al., Dose-response relationships between iron deficiency with or without anemia and infant social-emotional behavior. J Pediatr 152, 696, 2008.
18. Patel, M. S., Srinivasan, M., and Laychock, S. G., Nutrient-induced maternal hyperinsulinemia and metabolic programming in the progeny. Nestle Nutr Workshop Ser Pediatr Program 55, 137, 2005.