Equivalence of generic and brand-name drugs for cardiovascular disease

JAMA

Volumn 301, Issue 16, 2009, Pages 1654-

  Carter, Barry L ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENERIC DRUG; VERAPAMIL; ANTIARRHYTHMIC AGENT; CALCIUM CHANNEL BLOCKING AGENT; CARDIOVASCULAR AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; VERAPAMIL DERIVATIVE;

BIOEQUIVALENCE; CARDIOVASCULAR DISEASE; DRUG BIOAVAILABILITY; DRUG FORMULATION; DRUG SOLUBILITY; LETTER; PRIORITY JOURNAL; FOOD AND DRUG ADMINISTRATION; AGE; AGED; HUMAN; NOTE; PHARMACOKINETICS; STEREOISOMERISM; BLOOD PRESSURE REGULATION; DRUG ABSORPTION; DRUG METABOLISM; DRUG POTENCY;

AGE FACTORS; AGED; CALCIUM CHANNEL BLOCKERS; CARDIOVASCULAR AGENTS; DRUGS, GENERIC; HUMANS; THERAPEUTIC EQUIVALENCY; VERAPAMIL; STEREOISOMERISM;

EID: 84868927611     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.2009.520     Document Type: Letter

References (5)

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2. Carter BL, Gersema LM, Williams GO, Schabold K. Once-daily propranolol for hypertension: acomparison of regular-release, long-acting, and genericformulations. Pharmaco therapy. 1989;9(1):17-22.
3. Saseen JJ, Porter JA, Barnette DJ, Bauman JL, Zajac EJ Jr, Carter BL. Postabsorption concentration peaks with brand-name and generic verapamil: a doubleblind, crossover study in elderly hypertensive patients. J Cin Pharmacol. 1997; 37(6):526-534.
4. Carter BL, Noyes MA, Demmler RW. Differences in serum concentrations of and responses to generic verapamil in the elderly. Pharmacotherapy. 1993; 13(4):359-368.
5. Porter JE, Brown TE, Carter BL, Noyes MA, Demmler RW. Age and genderrelated differences in oral verapamil pharmacokinetics and pharmacodynamics. J Appl Ther. 1996;1:27-37. © 2009 American Medical Association.