Anti-inflammatory and antinociceptive effects of cordymin, a peptide purified from the medicinal mushroom Cordyceps sinensis

Natural Product Research

Volumn 26, Issue 24, 2012, Pages 2358-2362

  Qian, Gui Min ^a   Pan, Guo Feng ^b   Guo, Jian You ^c  

^a ZHEJIANG PHARMACEUTICAL COLLEGE   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c INSTITUTE OF PSYCHOLOGY   (China)

Author keywords

anti inflammatory; antinociceptive; cordymin; IL 1 ; neurolysin; TAOS; TNF

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTINOCICEPTIVE AGENT; ANTIOXIDANT; CORYDMIN; DICLOFENAC; HERBACEOUS AGENT; INTERLEUKIN 1BETA; NEUROLYSIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG PURIFICATION; ENZYME INHIBITION; FEMALE; HOT PLATE TEST; IC 50; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; MOUSE; NONHUMAN; OPHIOCORDYCEPS; REACTION TIME; STIMULUS RESPONSE; THERMAL STIMULATION; WRITHING TEST;

ACETIC ACID; ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS; COLIC; CORDYCEPS; DOSE-RESPONSE RELATIONSHIP, DRUG; HOT TEMPERATURE; INTERLEUKIN-1BETA; METALLOENDOPEPTIDASES; MICE; PEPTIDES; PLANT EXTRACTS; REACTION TIME; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

BASIDIOMYCOTA; CORDYCEPS SINENSIS; MUS;

EID: 84868703640     PISSN: 14786419     EISSN: 14786427     Source Type: Journal    
DOI: 10.1080/14786419.2012.658800     Document Type: Article

References (9)

1. Collier, HO, Dinneen, JC, Johnson, CA, and, Schneider, C. 1968. The abdominal constriction response and its suppression by analgesic drugs in the mouse. British Journal of Pharmacology and Chemotherapy, 32: 295-310.
2. Guo, JY, Wang, JY, and, Luo, F. 2010. Dissection of placebo analgesia in mice: The conditions for activation of opioid and non-opioid systems. Journal of Psychopharmacology, 24: 1561-1567.
3. Guo, JY, Yuan, XY, Sui, F, Zhang, WC, Wang, JY, Luo, F, and, Luo, J. 2011. Placebo analgesia affects the behavioral despair tests and hormonal secretions in mice. Psychopharmacology, 217: 83-90.
4. Koster, R, Anderson, M, and, DeBeer, EJ. 1959. Acetic acid for analgesic screening. Federation Proceedings, 18: 418-420.
5. Liu, Z, Li, P, Zhao, D, Tang, H, and, Guo, J. 2010. Protective effect of extract of Cordyceps sinensis in middle cerebral artery occlusion-induced focal cerebral ischemia in rats. Behavioral and Brain Functions, 6: 61
6. Tyler, BM, Cusack, B, Douglas, CL, Souder, T, and, Richelson, E. 1998. Evidence for additional neurotensin receptor subtypes: Neurotensin analogues that distinguish between neurotensin-mediated hypothermia and antinociception. Brain Research, 792: 246-252. (Pubitemid 28267537)
7. Wong, JH, Ng, TB, Wang, H, Sze, SC, Zhang, KY, Li, Q, and, Lu, X. 2011. Cordymin, an antifungal peptide from the medicinal fungus Cordyceps militaris. Phytomedicine, 18: 387-392.
8. Yuan, XY, Liu, W, Zhang, P, Wang, RY, and, Guo, JY. 2010. Effects and mechanisms of aloperine on 2,4-dinitrofluorobenzene-induced allergic contact dermatitis in BALB/c mice. European Journal of Pharmacology, 629: 147-152.
9. Zhu, JS, Halper, GM, and, Jones, K. 1998. The scientific rediscovery of an ancient Chinese herbal medicine: Cordyceps sinensis. Journal of Alternative and Complementary Medicine, 4: 289-303. (Pubitemid 128540688)