A strength exercise program in rats with epilepsy is protective against seizures

Epilepsy and Behavior

Volumn 25, Issue 3, 2012, Pages 323-328

  Peixinho Pena, Luiz Fernando ^a   Fernandes, Jansen ^a   de Almeida, Alexandre Aparecido ^a   Gomes, Fabiano Guimarães Novaes ^a   Cassilhas, Ricardo ^a   Venancio, Daniel Paulino ^a   de Mello, Marco Tulio ^a   Scorza, Fulvio Alexandre ^a   Cavalheiro, Esper Abrão ^a   Arida, Ricardo Mario ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Epilepsy; Exercise; Pilocarpine; Resistance training; Seizure; Strength training

Indexed keywords

PILOCARPINE;

AEROBIC EXERCISE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EPILEPTIC STATE; FLEXOR MUSCLE; MALE; MUSCLE HYPERTROPHY; NONHUMAN; RAT; RESISTANCE TRAINING; SEIZURE; SOMNOLENCE;

ANALYSIS OF VARIANCE; ANIMALS; DISEASE MODELS, ANIMAL; EPILEPSY; MALE; MUSCARINIC AGONISTS; MUSCLE FIBERS, SKELETAL; MYOSINS; PHYSICAL CONDITIONING, ANIMAL; PILOCARPINE; RATS; RATS, WISTAR; SEIZURES; TIME FACTORS;

EID: 84868693355     PISSN: 15255050     EISSN: 15255069     Source Type: Journal    
DOI: 10.1016/j.yebeh.2012.08.011     Document Type: Article

References (49)

1. Eriksen H.R., Bjørn E., Grønningsaeter H., Nakken K.O., Løyning Y., Ursin H. Physical exercise in women with intractable epilepsy. Epilepsia 1994, 35:1256-1264.
2. Nakken K.O., Bjorholt P.G., Johannesen S.L., Loyning T., Lind E. Effect of physical training on aerobic capacity, seizure occurrence, and serum level of antiepileptic drugs in adults with epilepsy. Epilepsia 1990, 31:88-94.
3. McAuley J.W., Long L., Heise J., et al. A prospective evaluation of the effects of a 12-week outpatient exercise program on clinical and behavioral outcomes in patients with epilepsy. Epilepsy Behav 2001, 2:592-600.
4. Camilo F., Scorza F.A., de Albuquerque M., Vancini R.L., Cavalheiro E.A., Arida R.M. Evaluation of intense physical effort in subjects with temporal lobe epilepsy. Arq Neuropsiquiatr 2009, 67:1007-1012.
5. Vancini R.L., de Lira C.A., Scorza F.A., et al. Cardiorespiratory and electroencephalographic responses to exhaustive acute physical exercise in people with temporal lobe epilepsy. Epilepsy Behav 2010, 19(3):504-508.
6. Arida R.M., de Jesus Vieira A., Cavalheiro E.A. Effect of physical exercise on kindling development. Epilepsy Res 1998, 30:127-132.
7. Arida R.M., Scorza F.A., dos Santos N.F., Peres C.A., Cavalheiro E.A. Effect of physical exercise on seizure occurrence in a model of temporal lobe epilepsy in rats. Epilepsy Res 1999, 37:45-52.
8. Arida R.M., Sanabria E.R., da Silva A.C., Faria L.C., Scorza F.A., Cavalheiro E.A. Physical training reverts hippocampal electrophysiological changes in rats submitted to the pilocarpine model of epilepsy. Physiol Behav 2004, 83:165-171.
9. Arida R.M., Scorza C.A., Scorza F.A., Gomes da Silva S., da Graça Naffah Mazzacoratti M., Cavalheiro E.A. Effects of different types of physical exercise on the staining of parvalbumin-positive neurons in the hippocampal formation of rats with epilepsy. Prog Neuropsychopharmacol Biol Psychiatry 2007, 31:814-822.
10. Arida R.M., Cavalheiro E.A., da Silva A.C., Scorza F.A. Physical activity and epilepsy: proven and predicted benefits. Sports Med 2008, 38(7):607-615.
11. Arida R.M., Scorza F.A., Scorza C.A., Cavalheiro E.A. Is physical activity beneficial for recovery in temporal lobe epilepsy? Evidences from animal studies. Neurosci Biobehav Rev 2009, 33:422-431.
12. Kohrt W.M., Bloomfield S.A., Little K.D., Nelson M.E., Yingling V.R. American College of Sports Medicine. American College of Sports Medicine position stand: physical activity and bone health. Med Sci Sports Exerc 2004, 36(11):1985-96.
13. Suominen H. Muscle training for bone strength. Aging Clin Exp Res 2006, 18(2):85-93.
14. Garber C.E., Blissmer B., Deschenes M.R., et al. American College of Sports Medicine. American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise. Med Sci Sports Exerc 2011, 43(7):1334-1359.
15. Kim E., Dear A., Ferguson S.L., Seo D., Bemben M.G. Effects of 4weeks of traditional resistance training vs. superslow strength training on early phase adaptations in strength, flexibility, and aerobic capacity in college-aged women. J Strength Cond Res 2011, 25(11):3006-3013.
16. Da Silva A., Almeida G.J.M., Cassilhas R.C., et al. Balance, coordination and agility of older individuals submitted to physical resisted exercises practice. Rev Bras Med Esporte 2008, 14(2). [cited 2011 Dec 29]. 10.1590/S1517-86922008000200001.
17. Cassilhas R.C., Antunes H.K., Tufik S., de Mello M.T. Mood, anxiety, and serum IGF-1 in elderly men given 24weeks of high resistance exercise. Percept Mot Skills 2010, 110(1):265-276.
18. Nelson M., Fiatarone M., Morganti C., Trice I., Greenberg R., Evans W. Effects of high-intensity strength training on multiple risk factors for osteoporotic fractures. JAMA 1994, 272:1909-1914.
19. Singh N., Clements K., Fiatarone M. A randomized controlled trial of progressive resistance training in depressed elders. J Gerontol 1997, 52:27-35.
20. Thomas K., Muir K., Doherty M., Jones A., O'Reilly S., Bassey E. Home based exercise programme for knee pain and knee osteoarthritis: randomized controlled trial. BMJ 2002, 325:752.
21. Castaneda C., Layne J., Munoz-Orians L., et al. A randomized control trial of progressive resistance exercise training in older adults with type-2 diabetes. Diabetes Care 2002, 25:235-241.
22. Buchner D., Cress M., de Lateur B., et al. The effect of strength and endurance training on gait, balance, fall risk, and health services use in community-living older adults. J Gerontol 1997, 52:218-224.
23. Cassilhas R.C., Lee K.S., Fernandes J., et al. Spatial memory is improved by aerobic and resistance exercise through divergent molecular mechanisms. Neuroscience 2012, 202:309-317.
24. Heise J., Buckworth J., McAuley J.W., Long L., Kirby T. Exercise training results in positive outcomes in persons with epilepsy. Clin Exerc Physiol 2002, 4:79-84.
25. Turski W.A., Cavalheiro E.A., Schwarz M., Czuczwar S.J., Kleinrok Z., Turski L. Limbic seizures produced by pilocarpine in rats: behavioural, electroencephalographic and neuropathological study. Behav Brain Res 1983, 9:315-335.
26. Yarasheski K.E., Lemon P.W., Gilloteaux J. Effect of heavy resistance exercise training on muscle fiber composition in young rats. J Appl Physiol 1990, 69:434-437.
27. Duncan N.D., Williams D.A., Lynch G.S. Adaptations in rat skeletal muscle following long-term resistance exercise training. Eur J Appl Physiol Occup Physiol 1998, 77:372-378.
28. Hornberger T.A., Farrar R.P. Physiological hypertrophy of the FHL muscle following 8weeks of progressive resistance exercise in the rat. Can J Appl Physiol 2004, 29:16-31.
29. Prestes J., de Cassia M.R., Shiguemoto G.E., et al. Effects of ovariectomy and resistance training on MMP-2 activity in skeletal muscle. Appl Physiol Nutr Metab 2009, 34:700-706.
30. Pereira G.B., Prestes J., Leite R.D., et al. Effects of ovariectomy and resistance training on MMP-2 activity in rat calcaneal tendon. Connect Tissue Res 2010, 51:459-466.
31. Turski W.A., Cavalheiro E.A., Turski L., Kleinrok Z. Intrahippocampal bethanechol in rats: behavioral, electroencephalographic and neuropathological correlates. Behav Brain Res 1983, 7:361-370.
32. Cavalheiro E.A., Leite J.P., Bortolotto Z.A., Turski W.A., Ikonomidou C., Turski L. Long-term effects of pilocarpine in rats: structural damage of the brain triggers kindling and spontaneous recurrent seizures. Epilepsia 1991, 32:778-782.
33. Arida R.M., Fernandes M.J., Scorza F.A., Preti S.C., Cavalheiro E.A. Physical training does not influence interictal LCMRglu in pilocarpine-treated rats with epilepsy. Physiol Behav 2003, 79:789-794.
34. Nakken K.O., Solaas M.H., Kjeldsen M.J., Friis M.L., Pellock J.M., Corey L.A. Which seizure-precipitating factors do patients with epilepsy most frequently report?. Epilepsy Behav 2005, 6:85-89.
35. Haut S.R., Hall C.B., Masur J., Lipton R.B. Seizure occurrence: precipitants and prediction. Neurology 2007, 69:1905-20.
36. Sperling M.R., Schilling C.A., Glosser D., Tracy J.I., Asadi-Pooya A.A. Self-perception of seizure precipitants and their relation to anxiety level, depression, and health locus of control in epilepsy. Seizure 2008, 17:302-307.
37. Götze W., Kubicki S., Munter M., Teichmann J. Effect of physical exercise on seizure threshold (investigated by electroencephalographic telemetry). Dis Nerv Syst 1967, 28:664-667.
38. Perrig-Chiello P., Perrig W.J., Ehrsam R., Staehelin H.B., Krings F. The effects of resistance training on well-being and memory in elderly volunteers. Age Ageing 1998, 27(4):469-475.
39. Heyn P.C., Johnson K.E., Kramer A.F. Endurance and strength training outcomes on cognitively impaired and cognitively intact older adults: a meta-analysis. J Nutr Health Aging 2008, 12(6):401-409.
40. Cassilhas R.C., Viana V.A., Grassmann V., et al. The impact of resistance exercise on the cognitive function of the elderly. Med Sci Sports Exerc 2007, 39(8):1401-1407.
41. Liu-Ambrose T., Nagamatsu L.S., Graf P., Beattie B.L., Ashe M.C., Handy T.C. Resistance training and executive functions: a 12-month randomized controlled trial. Arch Intern Med 2010, 170(2):170-178.
42. Bertram E.H., Cornett J.F. The evolution of a rat model of chronic spontaneous limbic seizures. Brain Res 1994, 661(1-2):157-162.
43. Quigg M., Straume M., Menaker M., Bertram E.H. Temporal distribution of partial seizures: comparison of an animal model with human partial epilepsy. Ann Neurol 1998, 43(6):748-755.
44. Arida R.M., Scorza F.A., Peres C.A., Cavalheiro E.A. The course of untreated seizures in the pilocarpine model of epilepsy. Epilepsy Res 1999, 34(2-3):99-107.
45. Hellier J.L., Dudek F.E. Spontaneous motor seizures of rats with kainate-induced epilepsy: effect of time of day and activity state. Epilepsy Res 1999, 35(1):47-57.
46. Bajorat R., Wilde M., Sellmann T., Kirschstein T., Köhling R. Seizure frequency in pilocarpine-treated rats is independent of circadian rhythm. Epilepsia 2011, 52(9):118-122.
47. Matos G., Tufik S., Scorza F.A., Cavalheiro E.A., Andersen M.L. Sleep, epilepsy and translational research: what can we learn from the laboratory bench?. Prog Neurobiol 2011, 95(3):396-405.
48. Goffin K., Nissinen J., Van Laere K., Pitkänen A. Cyclicity of spontaneous recurrent seizures in pilocarpine model of temporal lobe epilepsy in rat. Exp Neurol 2007, 205(2):501-505.
49. Matos G., Tsai R., Baldo M.V., de Castro I., Sameshima K., Valle A.C. The sleep-wake cycle in adult rats following pilocarpine-induced temporal lobe epilepsy. Epilepsy Behav 2010, 17(3):324-331.