Demographics, trends, and outcomes in pediatric acute myocarditis in the United States, 2006 to 2011

Circulation: Cardiovascular Quality and Outcomes

Volumn 5, Issue 5, 2012, Pages 622-627

  Ghelani, Sunil J ^a   Spaeder, Michael C ^a   Pastor, William ^a   Spurney, Christopher F ^a   Klugman, Darren ^a  

^a CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

Author keywords

Myocarditis; Outcome; Pediatrics; Regional variation

Indexed keywords

ACUTE DISEASE; ACUTE MYOCARDITIS; ADOLESCENT; ARTICLE; CARDIOVASCULAR MORTALITY; CHILD; DEMOGRAPHY; EXTRACORPOREAL OXYGENATION; FEMALE; HEART FUNCTION; HEART MUSCLE BIOPSY; HEART TRANSPLANTATION; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MYOCARDITIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; UNITED STATES; VENTRICULAR ASSIST DEVICE;

ACUTE DISEASE; ADOLESCENT; AGE DISTRIBUTION; AGE FACTORS; BIOPSY; CARDIOVASCULAR AGENTS; CHI-SQUARE DISTRIBUTION; CHILD; CHILD, PRESCHOOL; EXTRACORPOREAL MEMBRANE OXYGENATION; FEMALE; HEALTHCARE DISPARITIES; HEART TRANSPLANTATION; HEART-ASSIST DEVICES; HUMANS; INFANT; LINEAR MODELS; LOGISTIC MODELS; MAGNETIC RESONANCE IMAGING; MALE; MULTIVARIATE ANALYSIS; MYOCARDITIS; ODDS RATIO; PHYSICIAN'S PRACTICE PATTERNS; PREDICTIVE VALUE OF TESTS; RECOVERY OF FUNCTION; RESIDENCE CHARACTERISTICS; RETROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; SURVIVAL ANALYSIS; TIME FACTORS; TREATMENT OUTCOME; UNITED STATES; YOUNG ADULT;

EID: 84868657286     PISSN: 19417713     EISSN: 19417705     Source Type: Journal    
DOI: 10.1161/CIRCOUTCOMES.112.965749     Document Type: Article

References (24)

1. Cooper LT Jr. Myocarditis. N Engl J Med. 2009;360:1526-1538.
2. Smith NM, Bourne AJ, Clapton WK, Byard RW. The spectrum of presentation at autopsy of myocarditis in infancy and childhood. Pathology. 1992;24:129-131.
3. Wren C, O'Sullivan JJ, Wright C. Sudden death in children and adolescents. Heart. 2000;83:410-413. (Pubitemid 30316754)
4. Klugman D, Berger JT, Sable CA, He J, Khandelwal SG, Slonim AD. Pediatric patients hospitalized with myocarditis: A multi-institutional analysis. Pediatr Cardiol. 2010;31:222-228.
5. Baughman KL. Diagnosis of myocarditis: death of Dallas criteria. Circulation. 2006;113:593-595.
6. Aziz KU, Patel N, Sadullah T, Tasneem H, Thawerani H, Talpur S. Acute viral myocarditis: role of immunosuppression: A prospective randomised study. Cardiol Young. 2010;20:509-515.
7. Robinson JL, Hartling L, Crumley E, Vandermeer B, Klassen TP. A systematic review of intravenous gamma globulin for therapy of acute myocarditis. BMC Cardiovasc Disord. 2005;5:12.
8. Lee KJ, McCrindle BW, Bohn DJ, Wilson GJ, Taylor GP, Freedom RM, Smallhorn JF, Benson LN. Clinical outcomes of acute myocarditis in childhood. Heart. 1999;82:226-233. (Pubitemid 29362876)
9. Stiller B. Management of myocarditis in children: the current situation. Adv Exp Med Biol. 2008;609:196-215.
10. Wilmot I, Morales DL, Price JF, Rossano JW, Kim JJ, Decker JA, McGarry MC, Denfibro SW, Dreyer WJ, Towbin JA, Jefferies JL. Effectiveness of mechanical circulatory support in children with acute fulminant and persistent myocarditis. J Card Fail. 2011;17:487-494.
11. Hetzer R, Stiller B. Technology insight: Use of ventricular assist devices in children. Nat Clin Pract Cardiovasc Med. 2006;3:377-386. (Pubitemid 43978398)
12. Potapov E V, Stiller B, Hetzer R. Ventricular assist devices in children: current achievements and future perspectives. Pediatr Transplant. 2007;11:241-255. (Pubitemid 46570136)
13. Teele SA, Allan CK, Laussen PC, Newburger JW, Gauvreau K, Thiagarajan RR. Management and outcomes in pediatric patients presenting with acute fulminant myocarditis. J Pediatr. 2011;158:638-643.e1.
14. Duncan BW, Bohn DJ, Atz AM, French JW, Laussen PC, Wessel DL. Mechanical circulatory support for the treatment of children with acute fulminant myocarditis. J Thorac Cardiovasc Surg. 2001;122:440-448. (Pubitemid 32843941)
15. Friedrich MG, Sechtem U, Schulz-Menger J, Holmvang G, Alakija P, Cooper LT, White JA, Abdel-Aty H, Gutberlet M, Prasad S, Aletras A, Laissy JP, Paterson I, Filipchuk NG, Kumar A, Pauschinger M, Liu P; International Consensus Group on Cardiovascular Magnetic Resonance in Myocarditis. Cardiovascular magnetic resonance in myocarditis: A JACC White Paper. J Am Coll Cardiol. 2009;53:1475-1487.
16. Pophal SG, Sigfusson G, Booth KL, Bacanu SA, Webber SA, Ettedgui JA, Neches WH, Park SC. Complications of endomyocardial biopsy in children. J Am Coll Cardiol. 1999;34:2105-2110. (Pubitemid 30002672)
17. Drucker NA, Colan SD, Lewis AB, Beiser AS, Wessel DL, Takahashi M, Baker AL, Perez-Atayde AR, Newburger JW. Gamma-globulin treatment of acute myocarditis in the pediatric population. Circulation. 1994;89:252-257. (Pubitemid 24026497)
18. Mason JW, O'Connell JB, Herskowitz A, Rose NR, McManus BM, Billingham ME, Moon TE. A clinical trial of immunosuppressive therapy for myocarditis. The Myocarditis Treatment Trial Investigators. N Engl J Med. 1995;333:269-275.
19. Hia CP, Yip WC, Tai BC, Quek SC. Immunosuppressive therapy in acute myocarditis: An 18 year systematic review. Arch Dis Child. 2004;89:580-584.
20. Lyden D, Olszewski J, Huber S. Variation in susceptibility of Balb/c mice to coxsackievirus group B type 3-induced myocarditis with age. Cell Immunol. 1987;105:332-339. (Pubitemid 17074656)
21. Frisancho-Kiss S, Nyland JF, Davis SE, Frisancho JA, Barrett MA, Rose NR, Fairweather D. Sex differences in coxsackievirus B3-induced myocarditis: IL-12Rbeta1 signaling and IFN-gamma increase infilammation in males independent from STAT4. Brain Res. 2006;1126:139-147. (Pubitemid 44880925)
22. Huber SA, Kupperman J, Newell MK. Hormonal regulation of CD4 (+) T-cell responses in coxsackievirus B3-induced myocarditis in mice. J Virol. 1999;73:4689-4695. (Pubitemid 29246727)
23. Lyden DC, Olszewski J, Feran M, Job LP, Huber SA. Coxsackievirus B-3-induced myocarditis. Effect of sex steroids on viremia and infectivity of cardiocytes. Am J Pathol. 1987;126:432-438. (Pubitemid 17040671)
24. Costantini M, Oreto G, Albanese A, Ranieri A, De Fabrizio G, Sticchi I, Lauretti A, Capone S, Tritto C, Fachechi C, Renna R, Montinaro A, Pi-cano E. Presumptive myocarditis with ST-Elevation myocardial infarction presentation in young males as a new syndrome. Clinical significance and long term follow up. Cardiovasc Ultrasound. 2011;9:1.