Core antigen tests for hepatitis C virus: A meta-analysis

Molecular Biology Reports

Volumn 39, Issue 8, 2012, Pages 8197-8208

  Gu, Shuijun ^a   Liu, Jun ^a   Zhang, Huijun ^a   Gu, Baoluo ^a   Lai, Hanjiang ^a   Zhou, Hongliang ^a   He, Chaoqi ^a   Chen, Yingying ^b  

^a HANGZHOU NORMAL UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

Antibody; Core antigen; Diagnosis; Hepatitis C virus; Meta analysis

Indexed keywords

HEPATITIS C ANTIGEN; HEPATITIS C CORE ANTIGEN; UNCLASSIFIED DRUG; VIRUS RNA; CORE PROTEIN;

AGED; ANTIGEN DETECTION; ARTICLE; CHILD; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC KIT; DIAGNOSTIC TEST ACCURACY STUDY; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; IMMUNOASSAY; INTERMETHOD COMPARISON; NONHUMAN; PRESCHOOL CHILD; RNA ANALYSIS; SCREENING TEST; SENSITIVITY AND SPECIFICITY; SYSTEMATIC REVIEW; IMMUNOLOGICAL PROCEDURES; IMMUNOLOGY; META ANALYSIS; METHODOLOGY; PUBLISHING;

HEPATITIS C VIRUS;

HEPACIVIRUS; HEPATITIS C; HEPATITIS C ANTIGENS; HUMANS; IMMUNOLOGIC TESTS; PUBLICATION BIAS; SENSITIVITY AND SPECIFICITY; VIRAL CORE PROTEINS;

EID: 84868651861     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-012-1667-z     Document Type: Article

References (37)

1. Daniel HDJ, Vivekanandan P, Raghuraman S, Sridharan G, Chandy GM, Abraham P (2007) Significance of the hepatitis C virus (HCV) core antigen as an alternative plasma marker of active HCV infection. Indian J Med Microbiol 25(1):37-42
2. Bouvier-Alias M, Patel K, Dahari H, Beaucourt S, Larderie P, Blatt L, Hezode C, Picchio G, Dhumeaux D, Neumann AU, McHutchison JG, Pawlotsky JM (2002) Clinical utility of total HCV core antigen quantification: a new indirect marker of HCV replication. Hepatology 36(1):211-218. doi: 10.1053/jhep.2002. 34130
3. Chevaliez S, Pawlotsky JM (2008) Diagnosis and management of chronic viral hepatitis: antigens, antibodies and viral genomes. Best Pract Res Clin Gastroenterol 22(6):1031-1048. doi: 10.1016/j.bpg.2008.11.004
4. Pawlotsky J-M (2003) Use and interpretation of hepatitis C virus diagnostic assays. Clin Liver Dis 7(1):127-137
5. Forns X, Costa J (2006) HCV virological assessment. J Hepatol 44:S35-S39. doi: 10.1016/j.jhep.2005.11.010
6. Seme K, Poljak M, Babic DZ, Mocilnik T, Vince A (2005) The role of core antigen detection in management of hepatitis C: a critical review. J Clin Virol 32(2):92-101. doi: 10.1016/j.jcv.2004.10.005
7. Sanz C, Tassies D, Costa J, Freire C, Pereira A (2002) The first case of HCV infection detected before seroconversion in blood donors tested by HCV core antigen ELISA. Transfusion 42(4):505-506
8. Schnuriger A, Dominguez S, Valantin MA, Tubiana R, Duvivier C, Ghosn J, Simon A, Katlama C, Thibault V (2006) Early detection of hepatitis C virus infection by use of a new combined antigen-antibody detection assay: potential use for high-risk individuals. J Clin Microbiol 44(4):1561-1563. doi: 10.1128/jcm.44.4.1561-1563.2006
9. Leary TP, Gutierrez RA, Muerhoff AS, Birkenmeyer LG, Desai SM, Dawson GJ (2006) A chemiluminescent, magnetic particle-based immunoassay for the detection of hepatitis C virus core antigen in human serum or plasma. J Med Virol 78(11):1436-1440. doi: 10.1002/jmv.20716
10. Whiting P, Rutjes AWS, Reitsma JB, Bossuyt PMM, Kleijnen J (2003) The development of QUADAS: a tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews. BMC Med Res Methodol 3(1):25
11. Zamora J, Abraira V, Muriel A, Khan K, Coomarasamy A (2006) Meta-DiSc: a software for meta-analysis of test accuracy data. BMC Med Res Methodol 6(1):31
12. Lijmer JG, Bossuyt PMM, Heisterkamp SH (2002) Exploring sources of heterogeneity in systematic reviews of diagnostic tests. Stat Med 21(11):1525-1537
13. Egger M, Smith GD, Schneider M, Minder C (1997) Bias in meta-analysis detected by a simple, graphical test. British Med J 315(7109):629-634
14. Lu YC, Jiang ZY, Kuang YL, Chen WS, Tan YZ, Li DR (2007) Clinical value of the detection of hepatitisC virus core antigen. Chin J Cell Mol Immunol 23(7):635-637
15. Bouzgarrou N, Fodha I, Ben Othman S, Achour A, Grattard F, Trabelsi A, Pozzetto B (2005) Evaluation of a total core antigen assay for the diagnosis of hepatitis C virus infection in hemodialysis patients. J Med Virol 77(4):502-508. doi: 10.1002/jmv.20485
16. Zhu H, Zhang T, Fan CL, Xiao XG, Zhang FH (2010) Clinical significance of testing hepatitis C virus core antigen. J Dalian Med Univ 32(2):211-212
17. Fabrizi F, Lunghi G, Aucella F, Mangano S, Barbisoni F, Bisegna S, Vigilante D, Limido A, Martin P (2005) Novel assay using total hepatitis C virus (HCV) core antigen quantification for diagnosis of HCV infection in dialysis patients. J Clin Microbiol 43(1):414-420. doi: 10.1128/jcm.43.1.414-420.2005
18. Medhi S, Potukuchi SK, Polipalli SK, Swargiary SS, Deka P, Choudhary A, BegUin N, Hussain Z, Ahlawat RS, Kar P (2008) Diagnostic utility of hepatitis C virus core antigen in hemodialysis patients. Clin Biochem 41(7-8):447-452. doi: 10.1016/j.clinbiochem.2007.12.024
19. Xiao Z, Zhou G (2009) A comparative investigation on the detection of HCV antigen and the detection of its antibody as well as the HCV-RNA. Chinese J Zoonoses 25(6):539
20. Courouce AM, Le Marrec N, Bouchardeau F, Razer A, Maniez M, Laperche S, Simon N (2000) Efficacy of HCV core antigen detection during the preseroconversion period. Transfusion 40(10):1198-1202
21. Laperche S, Le Marrec N, Simon N, Bouchardeau F, Defer C, Maniez-Montreuil M, Levayer T, Zappitelli JP, Lefrere JJ (2003) A new HCV core antigen assay based on disassociation of immune complexes: an alternative to molecular biology in the diagnosis of early HCV infection. Transfusion 43(7):958-962
22. Agha S, Tanaka Y, Saudy N, Kurbanov F, Abo-Zeid M, EL-Malky M, Khalaf M, Ohta N, Yoshizawa H, Mizokami M (2004) Reliability of hepatitis C virus core antigen assay for detection of viremia in HCV genotypes 1, 2, 3, and 4 infected blood donors: a collaborative study between Japan, Egypt, and Uzbekistan. J Med Virol 73(2):216-222
23. Aoyagi K, Ohue C, Iida K, Kimura T, Tanaka E, Kiyosawa K, Yagi S (1999) Development of a simple and highly sensitive enzyme immunoassay for hepatitis C virus core antigen. J Clin Microbiol 37(6):1802-1808
24. Krajden M, Shivji R, Gunadasa K, Mak A, McNabb G, Friesenhahn M, Hendricks D, Comanor L (2004) Evaluation of the core antigen assay as a second-line supplemental test for diagnosis of active hepatitis C virus infection. J Clin Microbiol 42(9):4054-4059. doi: 10.1128/jcm.42.9.4054-4059. 2004
25. Long RX, Yang R, Bai HZ, Li H, Wang JJ, Liao Y, Tan ZG, Xie ZP (2010) HCV RNA and core antigen (HCV-cAg) analysis in HCV-Ab positive sample. J Med Res 39(12)
26. Netski DM, Wang XH, Mehta SH, Nelson K, Celentano D, Thongsawat S, Maneekarn N, Suriyanon V, Jittiwutikorn J, Thomas DL, Ticehurst JR (2004) Hepatitis C virus (HCV) core antigen assay to detect ongoing HCV infection in Thai injection drug users. J Clin Microbiol 42(4):1631-1636. doi: 10.1128/jcm.42.4.1631-1636.2004
27. Ouyang Y, Tan DM, Li TG, Zhou H, Tan C (2006) Qualitative detection of hepatitis C virus core antigen in the serum in patients with chronic hepatitis C. J Cent South Univ (Med Sci) 31(6):894-896
28. Tanaka E, Ohue C, Aoyagi K, Yamaguchi K, Yagi S, Kiyosawa K, Alter HJ (2000) Evaluation of a new enzyme immunoassay for hepatitis C virus (HCV) core antigen with clinical sensitivity approximating that of genomic amplification of HCV RNA. Hepatology 32(2):388-393
29. Valcavi P, Medici MC, Casula F, Arcangeletti MC, De Conto F, Pinardi F, Calderaro A, Chezzi C, Dettori G (2004) Evaluation of a total hepatitis C virus (HCV) core antigen assay for the detection of antigenaemia in anti-HCV positive individuals. J Med Virol 73(3):397-403. doi: 10.1002/jmv.20105
30. Kurtz JB, Boxall E, Qusir N, Shirley J, Coleman D, Chandler C (2001) The diagnostic significance of an assay for 'total' hepatitis C core antigen. J Virol Methods 96(2):127-132
31. Lorenzo J, Castro A, Aguilera A, Prieto E, Lopez-Calvo S, Regueiro B, Pedreira J (2004) Total HCV core antigen assay - a new marker of HCV viremia and its application during treatment of chronic hepatitis C. J Virol Methods 120(2):173-177. doi: 10.1016/j.viromet.2004.05.002
32. Zanetti AR, Romano L, Brunetto M, Colombo M, Bellati G, Tackney C (2003) Total HCV core antigen assay: a new marker of hepatitis C viremia for monitoring the progress of therapy. J Med Virol 70(1):27-30. doi: 10.1002/jmv.10355
33. Chen ZQ (2010) Clinical application of the detection technique of hepatitis C virus core antigen. J Pract Med Tech 01:14-16
34. Miedouge M, Saune K, Kamar N, Rieu M, Rostaing L, Izopet J (2010) Analytical evaluation of HCV core antigen and interest for HCV screening in haemodialysis patients. J Clin Virol 48(1):18-21. doi: 10.1016/j.jcv.2010.02.012
35. Reddy AK, Dakshinamurty KV, Lakshmi V (2006) Utility of HCV core antigen ELISA in the screening for hepatitis C virus infection in patients on hemodialysis. Indian J Med Microbiol 24(1):55-57
36. Yu JH, Zhou ZX, Zhang YC, Wang L, Zhou JY, Ji XH (2009) The value of HCVcAg detection by a sandwich-ELISA system in clinical diagnosis of HCV infection. Acta Univ Med Nanjing 29(11):1545-1549
37. Zhang HQ, Li SB, Wang GH, Chen K, Song XG, Feng XY (2007) Detection of hepatitis C virus core antigen for early diagnosis of hepatitis C virus infection in plasma donor in China. World J Gastroenterol 13(19):2738-2742