Prediction of inflicted brain injury in infants and children using retinal imaging

Pediatrics

Volumn 130, Issue 5, 2012, Pages

  Minns, Robert A ^a   Jones, Patricia A ^a   Tandon, Anamika ^a   Fleck, Brian W ^a   Mulvihill, Alan O ^a   Elton, Robert A ^b  

^a PRINCESS ALEXANDRA EYE PAVILION   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Infants and children; Inflicted brain injury; Predictive probability; Retinal hemorrhages

Indexed keywords

ACCIDENTAL TRAUMATIC BRAIN INJURY; ARTICLE; CHILD; DIFFERENTIAL DIAGNOSIS; EYE PHOTOGRAPHY; FEMALE; HOSPITAL ADMISSION; HUMAN; IMAGE ANALYSIS; INFANT; INFLICTED TRAUMATIC BRAIN INJURY; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; MEDICOLEGAL ASPECT; OBSERVATIONAL STUDY; OPTIC DISK; PREDICTION; PREDICTIVE VALUE; PRESCHOOL CHILD; PRIORITY JOURNAL; PROSPECTIVE STUDY; RETINA HEMORRHAGE; SENSITIVITY AND SPECIFICITY; TRAUMATIC BRAIN INJURY;

EID: 84868621747     PISSN: 00314005     EISSN: 10984275     Source Type: Journal    
DOI: 10.1542/peds.2011-3274     Document Type: Article

References (34)

1. Duhaime AC, Alario AJ, Lewander WJ, et al. Head injury in very young children: mechanisms, injury types, and ophthalmologic findings in 100 hospitalized patients younger than 2 years of age. Pediatrics. 1992;90 (2 Pt 1):179-185
2. Ewing-Cobbs L, Kramer L, Prasad M, et al. Neuroimaging, physical, and developmental findings after inflicted and noninflicted traumatic brain injury in young children. Pediatrics. 1998;102(2 pt 1):300-307 (Pubitemid 28354993)
3. Pierre-Kahn V, Roche O, Dureau P, et al. Ophthalmologic findings in suspected child abuse victims with subdural hematomas. Ophthalmology. 2003;110(9):1718-1723 (Pubitemid 37025429)
4. Bechtel K, Stoessel K, Leventhal JM, et al. Characteristics that distinguish accidental from abusive injury in hospitalized young children with head trauma. Pediatrics. 2004;114(1):165-168 (Pubitemid 38857581)
5. Vinchon M, Defoort-Dhellemmes S, Desurmont M, Dhellemmes P. Accidental and nonaccidental head injuries in infants: a prospective study. J Neurosurg . 2005;102 (4 suppl):380-384 (Pubitemid 44968473)
6. Betz P, Puschel K, Miltner E, Lignitz E, Eisenmenger W. Morphometrical analysis of retinal hemorrhages in the shaken baby syndrome. Forensic Sci Int. 1996;78(1):71- 80
7. Binenbaum G, Mirza-George N, Christian CW, Forbes BJ. Odds of abuse associated with retinal hemorrhages in children suspected of child abuse. J AAPOS. 2009;13(3): 268-272
8. Budenz DL, Farber MG, Mirchandani HG, Park H, Rorke LB. Ocular and optic nerve hemorrhages in abused infants with intracranial injuries. Ophthalmology. 1994; 101(3):559- 565
9. Gilles EE, McGregor ML, Levy-Clarke G. Retinal hemorrhage asymmetry in inflicted head injury: a clue to pathogenesis? J Pediatr. 2003;143(4):494-499 (Pubitemid 37352509)
10. Gilliland MGF. Extent and distribution of retinal hemorrhages in abusive and nonabusive head injury. In: Proceedings of the 55th. Annual Meeting of the American Academy of Forensic Sciences; Chicago, IL, February 17-22, 2003; Abstract G86:232-233
11. Kivlin JD, Simons KB, Lazoritz S, Ruttum MS. Shaken baby syndrome. Ophthalmology. 2000;107(7):1246-1254
12. Morad Y, Kim YM, Armstrong DC, Huyer D, Mian M, Levin AV. Correlation between retinal abnormalities and intracranial abnormalities in the shaken baby syndrome. Am J Ophthalmol. 2002;134(3):354- 359
13. Munger CE, Peiffer RL, Bouldin TW, Kylstra JA, Thompson RL. Ocular and associated neuropathologic observations in suspected whiplash shaken infant syndrome. A retrospective study of 12 cases. Am J Forensic Med Pathol. 1993;14(3):193- 200
14. Riffenburgh RS, Sathyavagiswaran L. Ocular findings at autopsy of child abuse victims. Ophthalmology. 1991;98(10):1519 - 1524
15. Wilkinson WS, Han DP, Rappley MD, Owings CL. Retinal hemorrhage predicts neurologic injury in the shaken baby syndrome. Arch Ophthalmol. 1989;107(10):1472-1474 (Pubitemid 19247251)
16. Fleck BW, Tandon A, Jones PA, Mulvihill AO, Minns RA. An interrater reliability study of a new 'zonal' classification for reporting the location of retinal haemorrhages in childhood for clinical, legal and research purposes. Br J Ophthalmol. 2010;94(7):886- 890
17. Mulvihill AO, Jones PA, Tandon A, Fleck BW, Minns RA. An inter-observer and intraobserver study of a classification of RetCam images of retinal haemorrhages in children. Br J Ophthalmol . 2011;95(1):99- 104
18. Tandon A, McIntyre S, Yu A, et al. Retinal haemorrhage description tool. Br J Ophthalmol. 2011;95(12):1719-1722
19. Mok JYQ, Busuttil A, Hammond HF. The joint paediatric-forensic examination in child abuse. Child Abuse Rev. 1998;7(3):194- 203
20. Keenan H. Nomenclature, definitions, incidence and demographics of inflicted childhood neurotrauma. In: Reece RM, Nicholson CE, eds. In fl icted Childhood Neurotrauma. Elk Groove City, IL: American Academy of Pediatrics; 2002:3-11
21. Thomas SA, Rosenfield NS, Leventhal JM, Markowitz RI. Long-bone fractures in young children: distinguishing accidental injuries from child abuse. Pediatrics. 1991;88(3): 471-476
22. Maguire S, Pickerd N, Farewell D, Mann M, Tempest V, Kemp AM. Which clinical features distinguish inflicted from noninflicted brain injury? A systematic review. Arch Dis Child. 2009;94(11):860-867
23. Maguire S, Moynihan S, Mann M, Potokar T, Kemp AM. A systematic review of the features that indicate intentional scalds in children. Burns. 2008;34(8):1072-1081
24. Bhardwaj G, Chowdhury V, Jacobs MB, Moran KT, Martin FJ, Coroneo MT. A systematic review of the diagnostic accuracy of ocular signs in pediatric abusive head trauma. Ophthalmology. 2010;117(5):983- 992.e17
25. Shaw AD, Watts P, Maguire S, Holden S, Mann M, Kemp AM. Are retinal findings in abused children different from those who suffer accidental head trauma? Results of a systematic review. J AAPOS. 2010;14(1): e27
26. Togioka BM, Arnold MA, Bathurst MA, et al. Retinal hemorrhages and shaken baby syndrome: an evidence-based review. J Emerg Med. 2009;37(1):98-106
27. Arlotti SA, Forbes BJ, Dias MS, Bonsall DJ. Unilateral retinal hemorrhages in shaken baby syndrome. J AAPOS. 2007;11(2):175- 178
28. Barry GP, Romero KE, Forbes BJ, Christian CW, Binenbaum G. Pathologic brain and head findings associated with retinal hemorrhages in young children with abusive or accidental head injuries. J AAPOS. 2010;14(1):e11
29. Healey K, Schrading W. A case of shaken baby syndrome with unilateral retinal hemorrhage with no associated intracranial hemorrhage. Am J Emerg Med. 2006;24(5):616-617 (Pubitemid 44287244)
30. Sturm V, Knecht PB, Landau K, Menke MN. Rare retinal haemorrhages in translational accidental head trauma in children. Eye (Lond). 2009;23(7):1535-1541
31. Trenchs V, Curcoy AI, Morales M, Serra A, Navarro R, Pou J. Retinal haemorrhages inhead trauma resulting from falls: differential diagnosis with non-accidental trauma in patients younger than 2 years of age. Childs Nerv Syst. 2008;24(7):815-820
32. Vinchon M, Noizet O, Defoort-Dhellemmes S, Soto-Ares G, Dhellemmes P. Infantile subdural hematomas due to traffic accidents. Pediatr Neurosurg. 2002;37(5):245 -253
33. Vinchon M, de Foort-Dhellemmes S, Desurmont M, Delestret I. Confessed abuse versus witnessed accidents in infants: comparison of clinical, radiological, and ophthalmological data in corroborated cases. Childs Nerv Syst. 2010;26(5):637-645
34. Dinakaran S, Chan TK, Rogers NK, Brosnahan DM. Retinal hemorrhages in meningococcal septicemia. J AAPOS . 2002;6(4): 221 -223