메뉴 건너뛰기




Volumn 28, Issue 11, 2012, Pages 1444-1457

The thai phase III HIV type 1 vaccine trial (RV144) regimen induces antibodies that target conserved regions within the V2 loop of gp120

(37)  Karasavvas, Nicos a   Billings, Erik b   Rao, Mangala c   Williams, Constance d   Zolla Pazner, Susan d,e   Bailer, Robert T f   Koup, Richard A f   Madnote, Sirinan a   Arworn, Duangnapa a   Shen, Xiaoying g   Tomaras, Georgia D g   Currier, Jeffrey R b   Jiang, Mike h   Magaret, Craig h   Andrews, Charla b   Gottardo, Raphael h   Gilbert, Peter h   Cardozo, Timothy J d   Rerks Ngarm, Supachai i   Nitayaphan, Sorachai a   more..


Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; GLYCOPROTEIN GP 120; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; PLACEBO; VALINE;

EID: 84868589536     PISSN: 08892229     EISSN: 19318405     Source Type: Journal    
DOI: 10.1089/aid.2012.0103     Document Type: Article
Times cited : (177)

References (69)
  • 1
    • 73349094086 scopus 로고    scopus 로고
    • Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand
    • Rerks-Ngarm S, Pitisuttithum P, Nitayaphan S, et al.: Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand. N Engl J Med 2009;361(23):2209-2220.
    • (2009) N Engl J Med , vol.361 , Issue.23 , pp. 2209-2220
    • Rerks-Ngarm, S.1    Pitisuttithum, P.2    Nitayaphan, S.3
  • 4
    • 20244383550 scopus 로고    scopus 로고
    • Safety and immunogenicity of an HIV subtype B and e prime-boost vaccine combination in HIV-negative Thai adults
    • Nitayaphan S, Pitisuttithum P, Karnasuta C, et al.: Safety and immunogenicity of an HIV subtype B and E prime-boost vaccine combination in HIV-negative Thai adults. J Infect Dis 2004;190(4):702-706.
    • (2004) J Infect Dis , vol.190 , Issue.4 , pp. 702-706
    • Nitayaphan, S.1    Pitisuttithum, P.2    Karnasuta, C.3
  • 5
    • 20044364751 scopus 로고    scopus 로고
    • Antibody-dependent cell-mediated cytotoxic responses in participants enrolled in a phase I/II ALVAC-HIV/AIDSVAX B/E prime-boost HIV-1 vaccine trial in Thailand
    • Karnasuta C, Paris RM, Cox JH, et al.: Antibody-dependent cell-mediated cytotoxic responses in participants enrolled in a phase I/II ALVAC-HIV/AIDSVAX B/E prime-boost HIV-1 vaccine trial in Thailand. Vaccine 2005;23(19):2522-2529.
    • (2005) Vaccine , vol.23 , Issue.19 , pp. 2522-2529
    • Karnasuta, C.1    Paris, R.M.2    Cox, J.H.3
  • 6
    • 0037444039 scopus 로고    scopus 로고
    • Immunogenicity of a recombinant human immunodeficiency virus (HIV)-canar-ypox vaccine in HIV-seronegative Ugandan volunteers: Results of the HIV Network for Prevention Trials 007 Vaccine Study
    • Cao H, Kaleebu P, Hom D, et al.: Immunogenicity of a recombinant human immunodeficiency virus (HIV)-canar-ypox vaccine in HIV-seronegative Ugandan volunteers: Results of the HIV Network for Prevention Trials 007 Vaccine Study. J Infect Dis 2003;187(6):887-895.
    • (2003) J Infect Dis , vol.187 , Issue.6 , pp. 887-895
    • Cao, H.1    Kaleebu, P.2    Hom, D.3
  • 7
    • 0036500532 scopus 로고    scopus 로고
    • Safety and immuno-genicity of a high-titered canarypox vaccine in combination with rgp120 in a diverse population of HIV-1-uninfected adults: AIDS Vaccine Evaluation Group Protocol 022A
    • Gupta K, Hudgens M, Corey L, et al.: Safety and immuno-genicity of a high-titered canarypox vaccine in combination with rgp120 in a diverse population of HIV-1-uninfected adults: AIDS Vaccine Evaluation Group Protocol 022A. J Acquir Immune Defic Syndr 2002;29(3):254-261.
    • (2002) J Acquir Immune Defic Syndr , vol.29 , Issue.3 , pp. 254-261
    • Gupta, K.1    Hudgens, M.2    Corey, L.3
  • 8
    • 0033496071 scopus 로고    scopus 로고
    • A canarypox vaccine expressing multiple human immunodeficiency virus type 1 genes given alone or with rgp120 elicits broad and durable CD8+ cytotoxic T lymphocyte responses in seronegative volunteers
    • Evans TG, Keefer MC, Weinhold KJ, et al.: A canarypox vaccine expressing multiple human immunodeficiency virus type 1 genes given alone or with rgp120 elicits broad and durable CD8+ cytotoxic T lymphocyte responses in seronegative volunteers. J Infect Dis 1999;180(2):290-298.
    • (1999) J Infect Dis , vol.180 , Issue.2 , pp. 290-298
    • Evans, T.G.1    Keefer, M.C.2    Weinhold, K.J.3
  • 9
    • 7844229165 scopus 로고    scopus 로고
    • Induction of immune responses to HIV-1 by canarypox virus (ALVAC) HIV-1 and gp120 SF-2 recombinant vaccines in uninfected volunteers. NIAID AIDS Vaccine Evaluation Group
    • Belshe RB, Gorse GJ, Mulligan MJ, et al.: Induction of immune responses to HIV-1 by canarypox virus (ALVAC) HIV-1 and gp120 SF-2 recombinant vaccines in uninfected volunteers. NIAID AIDS Vaccine Evaluation Group. AIDS 1998;12(18):2407-2415.
    • (1998) AIDS , vol.12 , Issue.18 , pp. 2407-2415
    • Belshe, R.B.1    Gorse, G.J.2    Mulligan, M.J.3
  • 10
    • 33845433434 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand
    • Pitisuttithum P, Gilbert P, Gurwith M, et al.: Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand. J Infect Dis 2006; 194(12):1661-1671.
    • (2006) J Infect Dis , vol.194 , Issue.12 , pp. 1661-1671
    • Pitisuttithum, P.1    Gilbert, P.2    Gurwith, M.3
  • 11
    • 13944254982 scopus 로고    scopus 로고
    • Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection
    • Flynn NM, Forthal DN, Harro CD, et al.: Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection. J Infect Dis 2005;191(5):654-665.
    • (2005) J Infect Dis , vol.191 , Issue.5 , pp. 654-665
    • Flynn, N.M.1    Forthal, D.N.2    Harro, C.D.3
  • 12
    • 13944250922 scopus 로고    scopus 로고
    • Correlation between immunologic responses to a recombinant glycoprotein 120 vaccine and incidence of HIV-1 infection in a phase 3 HIV-1 preventive vaccine trial
    • Gilbert PB, Peterson ML, Follmann D, et al.: Correlation between immunologic responses to a recombinant glycoprotein 120 vaccine and incidence of HIV-1 infection in a phase 3 HIV-1 preventive vaccine trial. J Infect Dis 2005;191(5):666-677.
    • (2005) J Infect Dis , vol.191 , Issue.5 , pp. 666-677
    • Gilbert, P.B.1    Peterson, M.L.2    Follmann, D.3
  • 13
    • 68349160853 scopus 로고    scopus 로고
    • Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques
    • Hessell AJ, Poignard P, Hunter M, et al.: Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques. Nat Med 2009;15(8):951-954.
    • (2009) Nat Med , vol.15 , Issue.8 , pp. 951-954
    • Hessell, A.J.1    Poignard, P.2    Hunter, M.3
  • 14
    • 0032907674 scopus 로고    scopus 로고
    • Neutralizing antibody directed against the HIV-1 envelope glycoprotein can completely block HIV-1/SIV chimeric virus infections of macaque monkeys
    • Shibata R, Igarashi T, Haigwood N, et al.: Neutralizing antibody directed against the HIV-1 envelope glycoprotein can completely block HIV-1/SIV chimeric virus infections of macaque monkeys. Nat Med 1999;5(2):204-210.
    • (1999) Nat Med , vol.5 , Issue.2 , pp. 204-210
    • Shibata, R.1    Igarashi, T.2    Haigwood, N.3
  • 15
    • 0033952103 scopus 로고    scopus 로고
    • Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection
    • Baba TW, Liska V, Hofmann-Lehmann R, et al.: Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection. Nat Med 2000;6(2):200-206.
    • (2000) Nat Med , vol.6 , Issue.2 , pp. 200-206
    • Baba, T.W.1    Liska, V.2    Hofmann-Lehmann, R.3
  • 16
    • 0033951746 scopus 로고    scopus 로고
    • Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies
    • Mascola JR, Stiegler G, VanCott TC, et al.: Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies. Nat Med 2000;6(2):207-210.
    • (2000) Nat Med , vol.6 , Issue.2 , pp. 207-210
    • Mascola, J.R.1    Stiegler, G.2    Vancott, T.C.3
  • 17
    • 84856482137 scopus 로고    scopus 로고
    • Vaccine protection against acquisition of neutralization-resistant siv challenges in rhesus monkeys
    • Barouch DH, Liu J, Li H, et al.: Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys. Nature 2012;482:89-93.
    • (2012) Nature , vol.482 , pp. 89-93
    • Barouch, D.H.1    Liu, J.2    Li, H.3
  • 18
    • 77952688015 scopus 로고    scopus 로고
    • Antibody-mediated protection against mucosal simian-human immunodeficiency virus challenge of macaques immunized with alphavirus replicon particles and boosted with trimeric envelope gly-coprotein in MF59 adjuvant
    • Barnett SW, Burke B, Sun Y, et al.: Antibody-mediated protection against mucosal simian-human immunodeficiency virus challenge of macaques immunized with alphavirus replicon particles and boosted with trimeric envelope gly-coprotein in MF59 adjuvant. J Virol 2010;84(12):5975-5985.
    • (2010) J Virol , vol.84 , Issue.12 , pp. 5975-5985
    • Barnett, S.W.1    Burke, B.2    Sun, Y.3
  • 19
    • 17344391461 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of hyperimmune anti-human immunodeficiency virus (HIV) immunoglobulin administered to HIV-infected pregnant women and their newborns. Pediatric AIDS Clinical Trials Group Protocol 185 Pharmacokinetic Study Group
    • Lambert JS, Mofenson LM, Fletcher CV, et al.: Safety and pharmacokinetics of hyperimmune anti-human immunodeficiency virus (HIV) immunoglobulin administered to HIV-infected pregnant women and their newborns. Pediatric AIDS Clinical Trials Group Protocol 185 Pharmacokinetic Study Group. J Infect Dis 1997;175(2):283-291.
    • (1997) J Infect Dis , vol.175 , Issue.2 , pp. 283-291
    • Lambert, J.S.1    Mofenson, L.M.2    Fletcher, C.V.3
  • 20
    • 84859393693 scopus 로고    scopus 로고
    • Immune-correlates analysis of an HIV-1 vaccine efficacy trial
    • Haynes BF, Gilbert PB, McElrath MJ, et al.: Immune-correlates analysis of an HIV-1 vaccine efficacy trial. N Engl J Med 2012;366(14):1275-1286.
    • (2012) N Engl J Med , vol.366 , Issue.14 , pp. 1275-1286
    • Haynes, B.F.1    Gilbert, P.B.2    McElrath, M.J.3
  • 21
    • 84863932778 scopus 로고    scopus 로고
    • Magnitude and breadth of the neutralizing antibody response in the RV144 and Vax003 HIV-1 vaccine efficacy trials
    • Montefiori DC, Karnasuta C, Huang Y, et al.: Magnitude and breadth of the neutralizing antibody response in the RV144 and Vax003 HIV-1 vaccine efficacy trials. J Infect Dis 2012; 206(3):431-441.
    • (2012) J Infect Dis , vol.206 , Issue.3 , pp. 431-441
    • Montefiori, D.C.1    Karnasuta, C.2    Huang, Y.3
  • 22
    • 13844302894 scopus 로고    scopus 로고
    • Structure of an un-liganded simian immunodeficiency virus gp120 core
    • Chen B, Vogan EM, Gong H, et al.: Structure of an un-liganded simian immunodeficiency virus gp120 core. Nature 2005;433(7028):834-841.
    • (2005) Nature , vol.433 , Issue.7028 , pp. 834-841
    • Chen, B.1    Vogan, E.M.2    Gong, H.3
  • 23
    • 39449098115 scopus 로고    scopus 로고
    • HIV-1 envelope protein binds to and signals through integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells
    • Arthos J, Cicala C, Martinelli E, et al.: HIV-1 envelope protein binds to and signals through integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells. Nat Immunol 2008;9(3):301-309.
    • (2008) Nat Immunol , vol.9 , Issue.3 , pp. 301-309
    • Arthos, J.1    Cicala, C.2    Martinelli, E.3
  • 24
    • 73949112038 scopus 로고    scopus 로고
    • The integrin al-pha4beta7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1
    • Cicala C, Martinelli E, McNally JP, et al.: The integrin al-pha4beta7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1. Proc Natl Acad Sci USA 2009;106(49):20877- 20882.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.49 , pp. 20877-20882
    • Cicala, C.1    Martinelli, E.2    McNally, J.P.3
  • 25
    • 77958115264 scopus 로고    scopus 로고
    • A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals
    • Walker LM, Simek MD, Priddy F, et al.: A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals. PLoS Pathog 2010;6(8).
    • (2010) PLoS Pathog , vol.6 , Issue.8
    • Walker, L.M.1    Simek, M.D.2    Priddy, F.3
  • 26
    • 77957198704 scopus 로고    scopus 로고
    • Variable loop glycan dependency of the broad and potent HIV-1-neutralizing antibodies PG9 and PG16
    • Doores KJ and Burton DR: Variable loop glycan dependency of the broad and potent HIV-1-neutralizing antibodies PG9 and PG16. J Virol 2010;84(20):10510- 10521.
    • (2010) J Virol , vol.84 , Issue.20 , pp. 10510-10521
    • Doores, K.J.1    Burton, D.R.2
  • 27
    • 79952368717 scopus 로고    scopus 로고
    • Structural comparison of HIV-1 envelope spikes with and without the V1/V2 loop
    • Hu G, Liu J, Taylor KA, and Roux KH: Structural comparison of HIV-1 envelope spikes with and without the V1/V2 loop. J Virol 2011;85(6):2741-2750.
    • (2011) J Virol , vol.85 , Issue.6 , pp. 2741-2750
    • Hu, G.1    Liu, J.2    Taylor, K.A.3    Roux, K.H.4
  • 28
    • 79955855015 scopus 로고    scopus 로고
    • Structural analysis of human and macaque mabs 2909 and 2.5b: Implications for the configuration of the quaternary neutralizing epitope of HIV-1 gp120
    • Spurrier B, Sampson JM, Totrov M, et al.: Structural analysis of human and macaque mAbs 2909 and 2.5B: Implications for the configuration of the quaternary neutralizing epitope of HIV-1 gp120. Structure 2011;19(5):691-699.
    • (2011) Structure , vol.19 , Issue.5 , pp. 691-699
    • Spurrier, B.1    Sampson, J.M.2    Totrov, M.3
  • 30
    • 33748925430 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 V1-V2 envelope loop sequences expand and add glycosylation sites over the course of infection, and these modifications affect antibody neutralization sensitivity
    • Sagar M, Wu X, Lee S, and Overbaugh J: Human immunodeficiency virus type 1 V1-V2 envelope loop sequences expand and add glycosylation sites over the course of infection, and these modifications affect antibody neutralization sensitivity. J Virol 2006;80(19):9586-9598.
    • (2006) J Virol , vol.80 , Issue.19 , pp. 9586-9598
    • Sagar, M.1    Wu, X.2    Lee, S.3    Overbaugh, J.4
  • 31
    • 70349686331 scopus 로고    scopus 로고
    • Limited neutralizing antibody specificities drive neutralization escape in early HIV-1 subtype C infection
    • Moore PL, Ranchobe N, Lambson BE, et al.: Limited neutralizing antibody specificities drive neutralization escape in early HIV-1 subtype C infection. PLoS Pathog 2009;5(9): e1000598.
    • (2009) PLoS Pathog , vol.5 , Issue.9
    • Moore, P.L.1    Ranchobe, N.2    Lambson, B.E.3
  • 32
    • 77957940271 scopus 로고    scopus 로고
    • Mutation at a single position in the V2 domain of the HIV-1 envelope protein confers neutralization sensitivity to a highly neutralization-resistant virus
    • O'Rourke SM, Schweighardt B, Phung P, et al.: Mutation at a single position in the V2 domain of the HIV-1 envelope protein confers neutralization sensitivity to a highly neutralization-resistant virus. J Virol 2010;84(21):11200-11209.
    • (2010) J Virol , vol.84 , Issue.21 , pp. 11200-11209
    • O'Rourke, S.M.1    Schweighardt, B.2    Phung, P.3
  • 33
    • 2342644898 scopus 로고    scopus 로고
    • The V1/V2 domain of gp120 is a global regulator of the sensitivity of primary human immunodeficiency virus type 1 isolates to neutralization by antibodies commonly induced upon infection
    • Pinter A, Honnen WJ, He Y, et al.: The V1/V2 domain of gp120 is a global regulator of the sensitivity of primary human immunodeficiency virus type 1 isolates to neutralization by antibodies commonly induced upon infection. J Virol 2004;78(10):5205-5215.
    • (2004) J Virol , vol.78 , Issue.10 , pp. 5205-5215
    • Pinter, A.1    Honnen, W.J.2    He, Y.3
  • 34
    • 77957569793 scopus 로고    scopus 로고
    • HIV-1 transmission biology: Selection and characteristics of infecting viruses
    • Sagar M: HIV-1 transmission biology: Selection and characteristics of infecting viruses. J Infect Dis 2010;202(Suppl 2): S289-2 96.
    • (2010) J Infect Dis , vol.202 , Issue.SUPPL. 2
    • Sagar, M.1
  • 35
    • 18144397438 scopus 로고    scopus 로고
    • Selection for human immunodeficiency virus type 1 envelope glycosylation variants with shorter V1-V2 loop sequences occurs during transmission of certain genetic subtypes and may impact viral RNA levels
    • Chohan B, Lang D, Sagar M, et al.: Selection for human immunodeficiency virus type 1 envelope glycosylation variants with shorter V1-V2 loop sequences occurs during transmission of certain genetic subtypes and may impact viral RNA levels. J Virol 2005;79(10):6528-6531.
    • (2005) J Virol , vol.79 , Issue.10 , pp. 6528-6531
    • Chohan, B.1    Lang, D.2    Sagar, M.3
  • 36
    • 12144289425 scopus 로고    scopus 로고
    • Envelope-constrained neutralization-sensitive HIV-1 after heterosexual transmission
    • Derdeyn CA, Decker JM, Bibollet-Ruche F, et al.: Envelope-constrained neutralization-sensitive HIV-1 after heterosexual transmission. Science 2004;303(5666):2019-2022.
    • (2004) Science , vol.303 , Issue.5666 , pp. 2019-2022
    • Derdeyn, C.A.1    Decker, J.M.2    Bibollet-Ruche, F.3
  • 37
    • 0029665856 scopus 로고    scopus 로고
    • Critical role for beta7 integrins in formation of the gut-associated lymphoid tissue
    • Wagner N, Lohler J, Kunkel EJ, et al.: Critical role for beta7 integrins in formation of the gut-associated lymphoid tissue. Nature 1996;382(6589):366- 370.
    • (1996) Nature , vol.382 , Issue.6589 , pp. 366-370
    • Wagner, N.1    Lohler, J.2    Kunkel, E.J.3
  • 38
    • 0034609968 scopus 로고    scopus 로고
    • T-cell function and migration. Two sides of the same coin
    • von Andrian UH and Mackay CR: T-cell function and migration. Two sides of the same coin. N Engl J Med 2000; 343(14):1020-1034.
    • (2000) N Engl J Med , vol.343 , Issue.14 , pp. 1020-1034
    • Von Andrian, U.H.1    MacKay, C.R.2
  • 39
    • 84863696607 scopus 로고    scopus 로고
    • Transmittedfounder and chronic subtype c HIV-1 use cd4 and ccr5 receptors with equal efficiency and are not inhibited by blocking the integrin alpha4beta7
    • Parrish NF, Wilen CB, Banks LB, et al.: Transmitted/founder and chronic subtype C HIV-1 use CD4 and CCR5 receptors with equal efficiency and are not inhibited by blocking the integrin alpha4beta7. PLoS Pathog 2012;8(5):e1002686.
    • (2012) PLoS Pathog , vol.8 , Issue.5
    • Parrish, N.F.1    Wilen, C.B.2    Banks, L.B.3
  • 40
    • 70349887757 scopus 로고    scopus 로고
    • Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target
    • Walker LM, Phogat SK, Chan-Hui PY, et al.: Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target. Science 2009;326(5950):285-289.
    • (2009) Science , vol.326 , Issue.5950 , pp. 285-289
    • Walker, L.M.1    Phogat, S.K.2    Chan-Hui, P.Y.3
  • 41
    • 77954100808 scopus 로고    scopus 로고
    • Structure-function relationships of HIV-1 envelope sequence-variable regions refocus vaccine design
    • Zolla-Pazner S and Cardozo T: Structure-function relationships of HIV-1 envelope sequence-variable regions refocus vaccine design. Nat Rev Immunol 2010;10(7):527-535.
    • (2010) Nat Rev Immunol , vol.10 , Issue.7 , pp. 527-535
    • Zolla-Pazner, S.1    Cardozo, T.2
  • 42
    • 79952396269 scopus 로고    scopus 로고
    • Crystal structure of human antibody 2909 reveals conserved features of quaternary structure-specific antibodies that potently neutralize HIV-1
    • Changela A, Wu X, Yang Y, et al.: Crystal structure of human antibody 2909 reveals conserved features of quaternary structure-specific antibodies that potently neutralize HIV-1. J Virol 2011;85(6):2524-2535.
    • (2011) J Virol , vol.85 , Issue.6 , pp. 2524-2535
    • Changela, A.1    Wu, X.2    Yang, Y.3
  • 43
    • 79952579682 scopus 로고    scopus 로고
    • Potent and broad neutralization of HIV-1 subtype C by plasma antibodies targeting a quaternary epitope including residues in the V2 loop
    • Moore PL, Gray ES, Sheward D, et al.: Potent and broad neutralization of HIV-1 subtype C by plasma antibodies targeting a quaternary epitope including residues in the V2 loop. J Virol 2011;85(7):3128-3141.
    • (2011) J Virol , vol.85 , Issue.7 , pp. 3128-3141
    • Moore, P.L.1    Gray, E.S.2    Sheward, D.3
  • 44
    • 16244419386 scopus 로고    scopus 로고
    • Identification of a new quaternary neutralizing epitope on human immunodeficiency virus type 1 virus particles
    • Gorny MK, Stamatatos L, Volsky B, et al.: Identification of a new quaternary neutralizing epitope on human immunodeficiency virus type 1 virus particles. J Virol 2005;79(8):5232-5237.
    • (2005) J Virol , vol.79 , Issue.8 , pp. 5232-5237
    • Gorny, M.K.1    Stamatatos, L.2    Volsky, B.3
  • 45
    • 33846556067 scopus 로고    scopus 로고
    • Type-specific epitopes targeted by monoclonal antibodies with exceptionally potent neutralizing activities for selected strains of human immunodeficiency virus type 1 map to a common region of the V2 domain of gp120 and differ only at single positions from the clade B consensus sequence
    • Honnen WJ, Krachmarov C, Kayman SC, et al.: Type-specific epitopes targeted by monoclonal antibodies with exceptionally potent neutralizing activities for selected strains of human immunodeficiency virus type 1 map to a common region of the V2 domain of gp120 and differ only at single positions from the clade B consensus sequence. J Virol 2007;81(3):1424-1432.
    • (2007) J Virol , vol.81 , Issue.3 , pp. 1424-1432
    • Honnen, W.J.1    Krachmarov, C.2    Kayman, S.C.3
  • 46
    • 77949411309 scopus 로고    scopus 로고
    • Quaternary epitope specificities of anti-HIV-1 neutralizing antibodies generated in rhesus macaques infected by the simian/human immunodeficiency virus SHIVSF162P4
    • Robinson JE, Franco K, Elliott DH, et al.: Quaternary epitope specificities of anti-HIV-1 neutralizing antibodies generated in rhesus macaques infected by the simian/human immunodeficiency virus SHIVSF162P4. J Virol 2010;84(7):3443-3453.
    • (2010) J Virol , vol.84 , Issue.7 , pp. 3443-3453
    • Robinson, J.E.1    Franco, K.2    Elliott, D.H.3
  • 47
    • 83455254775 scopus 로고    scopus 로고
    • Structure of HIV-1 gp120 v1v2 domain with broadly neutralizing antibody pg9
    • McLellan JS, Pancera M, Carrico C, et al.: Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature 2011;480:336-343.
    • (2011) Nature , vol.480 , pp. 336-343
    • McLellan, J.S.1    Pancera, M.2    Carrico, C.3
  • 48
    • 0028027741 scopus 로고
    • Human anti-V2 monoclonal antibody that neutralizes primary but not laboratory isolates of human immunodeficiency virus type 1
    • Gorny MK, Moore JP, Conley AJ, et al.: Human anti-V2 monoclonal antibody that neutralizes primary but not laboratory isolates of human immunodeficiency virus type 1. J Virol 1994;68(12):8312-8320.
    • (1994) J Virol , vol.68 , Issue.12 , pp. 8312-8320
    • Gorny, M.K.1    Moore, J.P.2    Conley, A.J.3
  • 49
    • 84861173075 scopus 로고    scopus 로고
    • The Thai phase III trial (RV144) vaccine regimen induces T cell responses that preferentially target epitopes within the V2 region of HIV-1 envelope
    • de Souza MS, Ratto-Kim S, Chuenarom W, et al.: The Thai phase III trial (RV144) vaccine regimen induces T cell responses that preferentially target epitopes within the V2 region of HIV-1 envelope. J Immunol 2012;188(10):5166- 5176.
    • (2012) J Immunol , vol.188 , Issue.10 , pp. 5166-5176
    • De Souza, M.S.1    Ratto-Kim, S.2    Chuenarom, W.3
  • 50
    • 85081768789 scopus 로고    scopus 로고
    • Sequence analysis of HIV-1 breakthrough infections in the RV144 Trial
    • Bangkok, Thailand, September 12-15 Abstract
    • Rolland M, Larsen B, and Edlefsen P: Sequence Analysis of HIV-1 Breakthrough Infections in the RV144 Trial. Presented at AIDS Vaccine 2011, Bangkok, Thailand, September 12-15, 2011. Abstract.
    • (2011) Presented at AIDS Vaccine 2011
    • Rolland, M.1    Larsen, B.2    Edlefsen, P.3
  • 51
    • 0037189323 scopus 로고    scopus 로고
    • Diversity considerations in HIV-1 vaccine selection
    • Gaschen B, Taylor J, Yusim K, et al.: Diversity considerations in HIV-1 vaccine selection. Science 2002;296(5577):2354-2360.
    • (2002) Science , vol.296 , Issue.5577 , pp. 2354-2360
    • Gaschen, B.1    Taylor, J.2    Yusim, K.3
  • 52
    • 0032474777 scopus 로고    scopus 로고
    • New chemical descriptors relevant for the design of biologically active peptides. A multivariate characterization of 87 amino acids
    • Sandberg M, Eriksson L, Jonsson J, et al.: New chemical descriptors relevant for the design of biologically active peptides. A multivariate characterization of 87 amino acids. J Med Chem 1998;41(14):2481-2491.
    • (1998) J Med Chem , vol.41 , Issue.14 , pp. 2481-2491
    • Sandberg, M.1    Eriksson, L.2    Jonsson, J.3
  • 53
    • 77949576511 scopus 로고    scopus 로고
    • RMAT-an rbio-conductor package for analyzing chip-chip experiments
    • Droit A, Cheung C, and Gottardo R: rMAT-an R/Bio-conductor package for analyzing ChIP-chip experiments. Bioinformatics 2010;26(5):678-679.
    • (2010) Bioinformatics , vol.26 , Issue.5 , pp. 678-679
    • Droit, A.1    Cheung, C.2    Gottardo, R.3
  • 54
    • 84862764447 scopus 로고    scopus 로고
    • Risk behaviour and time as covariates for efficacy of the HIV vaccine regimen alvac-hiv (vcp1521) and aidsvax be: A post-hoc analysis of the thai phase 3 efficacy trial rv 144
    • Robb ML, Rerks-Ngarm S, Nitayaphan S, et al.: Risk behaviour and time as covariates for efficacy of the HIV vaccine regimen ALVAC-HIV (vCP1521) and AIDSVAX B/E: A post-hoc analysis of the Thai phase 3 efficacy trial RV 144. Lancet Infect Dis 2012;12(7):531-537.
    • (2012) Lancet Infect Dis , vol.12 , Issue.7 , pp. 531-537
    • Robb, M.L.1    Rerks-Ngarm, S.2    Nitayaphan, S.3
  • 55
    • 84856458868 scopus 로고    scopus 로고
    • Case control study of the RV144 trial for immune correlates: The analysis and way forward
    • Bangkok, Thailand, September 12-15
    • Haynes BF: Case Control Study of the RV144 Trial for Immune Correlates: The Analysis and Way Forward. Presented at AIDS Vaccine 2011, Bangkok, Thailand, September 12-15, 2011.
    • (2011) Presented at AIDS Vaccine 2011
    • Haynes, B.F.1
  • 56
    • 85081761608 scopus 로고    scopus 로고
    • HIV-1 Envelope Antibodies Induced by ALVAC-AIDSVAX B/E Vaccine Target a Site of Vaccine Immune Pressure Within the C b Strand of gp120 V1V2
    • Keystone, Colorado, March 21-26 Abstract
    • Liao H-X, Bonsignori M, Alam SM, et al.: HIV-1 Envelope Antibodies Induced by ALVAC-AIDSVAX B/E Vaccine Target a Site of Vaccine Immune Pressure Within the C b Strand of gp120 V1V2. Presented at Keystone Symposia 2012, Keystone, Colorado, March 21-26, 2012. Abstract.
    • (2012) Presented at Keystone Symposia 2012
    • Liao, H.-X.1    Bonsignori, M.2    Alam, S.M.3
  • 57
    • 0031953399 scopus 로고    scopus 로고
    • Antigenicity of linear and cyclic peptides mimicking the disulfide loops in HIV-2 envelope glycoprotein: Synthesis, reoxidation and purification
    • Belhadj Jrad B and Bahraoui E: Antigenicity of linear and cyclic peptides mimicking the disulfide loops in HIV-2 envelope glycoprotein: Synthesis, reoxidation and purification. J Pept Res 1998;51(5):370-385.
    • (1998) J Pept Res , vol.51 , Issue.5 , pp. 370-385
    • Belhadj Jrad, B.1    Bahraoui, E.2
  • 58
    • 0041856083 scopus 로고    scopus 로고
    • A novel cyclic peptide immunization strategy for preventing HIV-1/AIDS infection and progression
    • Misumi S, Endo M, Mukai R, et al.: A novel cyclic peptide immunization strategy for preventing HIV-1/AIDS infection and progression. J Biol Chem 2003;278(34):32335-32343.
    • (2003) J Biol Chem , vol.278 , Issue.34 , pp. 32335-32343
    • Misumi, S.1    Endo, M.2    Mukai, R.3
  • 59
    • 0033030771 scopus 로고    scopus 로고
    • The effect of conformation on the solution stability of linear vs. cyclic RGD peptides
    • Bogdanowich-Knipp SJ, Jois DS, and Siahaan TJ: The effect of conformation on the solution stability of linear vs. cyclic RGD peptides. J Pept Res 1999;53(5):523-529.
    • (1999) J Pept Res , vol.53 , Issue.5 , pp. 523-529
    • Bogdanowich-Knipp, S.J.1    Jois, D.S.2    Siahaan, T.J.3
  • 60
    • 12244305521 scopus 로고    scopus 로고
    • Conformational study of linear and cyclic peptides corresponding to the 276-284 epitope region of HSV gD-1
    • Mezo G, Majer Z, Vass E, et al.: Conformational study of linear and cyclic peptides corresponding to the 276-284 epitope region of HSV gD-1. Biophys Chem 2003;103(1):51-65.
    • (2003) Biophys Chem , vol.103 , Issue.1 , pp. 51-65
    • Mezo, G.1    Majer, Z.2    Vass, E.3
  • 61
    • 0029120129 scopus 로고
    • Conjugates of synthetic cyclic peptides elicit bactericidal antibodies against a conformational epitope on a class 1 outer membrane protein of Neisseria meningitidis
    • Hoogerhout P, Donders EM, van Gaans-van den Brink JA, et al.: Conjugates of synthetic cyclic peptides elicit bactericidal antibodies against a conformational epitope on a class 1 outer membrane protein of Neisseria meningitidis. Infect Immun 1995;63(9):3473-3478.
    • (1995) Infect Immun , vol.63 , Issue.9 , pp. 3473-3478
    • Hoogerhout, P.1    Donders, E.M.2    Van Gaans-Van Den Brink, J.A.3
  • 62
    • 0032949148 scopus 로고    scopus 로고
    • Comparison of the antibody repertoire generated in healthy volunteers following immunization with a monomeric recombinant gp120 construct derived from a CCR5/CXCR4-using human immunodeficiency virus type 1 isolate with sera from naturally infected individuals
    • Beddows S, Lister S, Cheingsong R, et al.: Comparison of the antibody repertoire generated in healthy volunteers following immunization with a monomeric recombinant gp120 construct derived from a CCR5/CXCR4-using human immunodeficiency virus type 1 isolate with sera from naturally infected individuals. J Virol 1999;73(2):1740-1745.
    • (1999) J Virol , vol.73 , Issue.2 , pp. 1740-1745
    • Beddows, S.1    Lister, S.2    Cheingsong, R.3
  • 63
    • 64049089430 scopus 로고    scopus 로고
    • Quantitating the multiplicity of infection with human immunodeficiency virus type 1 subtype C reveals a non-Poisson distribution of transmitted variants
    • Abrahams MR, Anderson JA, Giorgi EE, et al.: Quantitating the multiplicity of infection with human immunodeficiency virus type 1 subtype C reveals a non-Poisson distribution of transmitted variants. J Virol 2009;83(8):3556-3567.
    • (2009) J Virol , vol.83 , Issue.8 , pp. 3556-3567
    • Abrahams, M.R.1    Anderson, J.A.2    Giorgi, E.E.3
  • 64
    • 61849171106 scopus 로고    scopus 로고
    • Selection of HIV variants with signature genotypic characteristics during heterosexual transmission
    • Sagar M, Laeyendecker O, Lee S, et al.: Selection of HIV variants with signature genotypic characteristics during heterosexual transmission. J Infect Dis 2009;199(4):580-589.
    • (2009) J Infect Dis , vol.199 , Issue.4 , pp. 580-589
    • Sagar, M.1    Laeyendecker, O.2    Lee, S.3
  • 65
    • 33846552274 scopus 로고    scopus 로고
    • Role of V1V2 and other human immunodeficiency virus type 1 envelope domains in resistance to autologous neutralization during clade C infection
    • Rong R, Bibollet-Ruche F, Mulenga J, et al.: Role of V1V2 and other human immunodeficiency virus type 1 envelope domains in resistance to autologous neutralization during clade C infection. J Virol 2007;81(3):1350-1359.
    • (2007) J Virol , vol.81 , Issue.3 , pp. 1350-1359
    • Rong, R.1    Bibollet-Ruche, F.2    Mulenga, J.3
  • 66
    • 79952232940 scopus 로고    scopus 로고
    • The genotype of early-transmitting HIV gp120s promotes alphabeta-reactivity revealing alphabetacd4+ t cells as key targets in mucosal transmission
    • Nawaz F, Cicala C, Van Ryk D, et al.: The genotype of early-transmitting HIV gp120s promotes alphabeta-reactivity, revealing alphabetaCD4+ T cells as key targets in mucosal transmission. PLoS Pathog 2011;7(2):e1001301.
    • (2011) PLoS Pathog , vol.7 , Issue.2
    • Nawaz, F.1    Cicala, C.2    Van Ryk, D.3
  • 67
    • 79251526530 scopus 로고    scopus 로고
    • HIV-1 envelope, integrins and co-receptor use in mucosal transmission of HIV
    • Cicala C, Arthos J, and Fauci AS: HIV-1 envelope, integrins and co-receptor use in mucosal transmission of HIV. J Transl Med 2010;9(Suppl 1):S2.
    • (2010) J Transl Med , vol.9 , Issue.SUPPL. 1
    • Cicala, C.1    Arthos, J.2    Fauci, A.S.3
  • 68
    • 0031023939 scopus 로고    scopus 로고
    • Prevalence of a V2 epitope in clade B primary isolates and its recognition by sera from HIV-1-infected individuals
    • Israel ZR, Gorny MK, Palmer C, et al.: Prevalence of a V2 epitope in clade B primary isolates and its recognition by sera from HIV-1-infected individuals. AIDS 1997;11(1):128-130.
    • (1997) AIDS , vol.11 , Issue.1 , pp. 128-130
    • Israel, Z.R.1    Gorny, M.K.2    Palmer, C.3
  • 69
    • 0023217711 scopus 로고
    • Functional regions of the envelope glycoprotein of human immunodeficiency virus type 1
    • Kowalski M, Potz J, Basiripour L, et al.: Functional regions of the envelope glycoprotein of human immunodeficiency virus type 1. Science 1987;237(4820):1351-1355.
    • (1987) Science , vol.237 , Issue.4820 , pp. 1351-1355
    • Kowalski, M.1    Potz, J.2    Basiripour, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.