DigiFab interacts with endogenous cardiotonic steroids and reverses preeclampsia-induced Na/K-ATPase inhibition

Reproductive Sciences

Volumn 19, Issue 12, 2012, Pages 1260-1267

  Ishkaraeva Yakovleva, Valentina V ^a   Fedorova, Olga V ^b   Solodovnikova, Nelly G ^a   Frolova, Elena V ^c   Bzhelyansky, Anton M ^b   Emelyanov, Igor V ^a   Adair, C David ^d   Zazerskaya, Irina E ^a   Bagrov, Alexei Y ^b  

^a ALMAZOV NATIONAL MEDICAL RESEARCH CENTRE   (Russian Federation)

^b NATIONAL INSTITUTE ON AGING   (United States)

^c SECHENOV INSTITUTE OF EVOLUTIONARY PHYSIOLOGY AND BIOCHEMISTRY   (Russian Federation)

^d UNIVERSITY OF TENNESSEE AT CHATTANOOGA   (United States)

Author keywords

cardiotonic steroids; digibind; DigiFab; immunotherapy; marinobufagenin; monoclonal antibody; Na K ATPase; preeclampsia

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM) INHIBITOR; ANTI MARINOBUFAGENIN MONOCLONAL ANTIBODY; BUFALIN; CARDIOTONIC AGENT; CINOBUFAGIN; DIGITOXIN; DIGOXIN; DIGOXIN ANTIBODY F(AB) FRAGMENT; MARINOBUFAGENIN; MONOCLONAL ANTIBODY; OUABAGENIN; OUABAIN; PREDNISONE; PROGESTERONE; PROSCILLARIDIN; STEROID; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BLOOD PRESSURE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; ERYTHROCYTE; FEMALE; GESTATIONAL AGE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IMMUNOASSAY; IMMUNOREGULATION; PATHOGENESIS; PREECLAMPSIA; PRIORITY JOURNAL;

ADULT; ANTIBODIES, MONOCLONAL; BUFANOLIDES; CARDIAC GLYCOSIDES; ENZYME INHIBITORS; ERYTHROCYTES; FEMALE; GESTATIONAL AGE; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; IMMUNOTHERAPY; PRE-ECLAMPSIA; PREGNANCY; SODIUM-POTASSIUM-EXCHANGING ATPASE;

EID: 84868568036     PISSN: 19337191     EISSN: 19337205     Source Type: Journal    
DOI: 10.1177/1933719112447124     Document Type: Article

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