A case series of five Sri Lankan patients with ovotesticular disorder of sex development

Clinical Pediatric Endocrinology

Volumn 21, Issue 4, 2012, Pages 69-73

  Wettasinghe, Kalum T ^a   Sirisena, Nirmala D ^a   Andraweera, Prabha H ^a   Jayasekara, Rohan W ^a   Dissanayake, Vajira H W ^a  

^a UNIVERSITY OF COLOMBO   (Sri Lanka)

Author keywords

Ambiguous genitalia; Disorder of sex development; Ovotestis; True hermaphroditism

Indexed keywords

ABDOMINAL MASS; ADULT; AMBIGUOUS GENITALIA; ARTICLE; CASE STUDY; CHILD; CLINICAL ARTICLE; CLINICAL FEATURE; CYTOGENETICS; FEMINIZATION; HISTOPATHOLOGY; HUMAN; HYPOSPADIAS; INFANT; INGUINAL HERNIA; KARYOTYPE 46,XX; KARYOTYPE 46,XY; MALE; PRESCHOOL CHILD; SEX DIFFERENTIATION DISORDER; SRI LANKA; SYMPTOM; TESTIS ATROPHY;

EID: 84868546747     PISSN: 09185739     EISSN: 13477358     Source Type: Journal    
DOI: 10.1297/cpe.21.69     Document Type: Article

References (15)

1. Hadjiathanasiou CG, Brauner R, Lortat-Jacob S, Nivot S, Jaubert F, Fellous M, et al. True hermaphroditism: genetic variants and clinical management. J Pediatr 1994;125(5 Pt 1):738-744.
2. Hughes IA, Houk C, Ahmed SF, Lee PA. Consensus statement on management of intersex disorders. Arch Dis Child 2006;91:554-563.
3. Krob G, Braun A, Kuhnle U. True hermaphroditism: geographical distribution, clinical fndings, chromosomes and gonadal histology. Eur J Pediatr 1994;153:2-10.
4. Bhansali A, Mahadevan S, Singh R, Rao KL, Garewal G. True hermaphroditism: clinical profle and management of six patients from North India. J Obstet Gynaecol 2006;26:348-350.
5. Pleskacova J, Hersmus R, Oosterhuis JW, Setyawati BA, Faradz SM, Cools M, et al. Tumor risk in disorders of sex development. Sex Dev 2010;4:259-269.
6. Rosenberg HS, Clayton GW, Hsu TC. Familial true hermaphroditism. J Clin Endocrinol Metab 1963;23:203-206.
7. Gallegos AJ, Guizar E, Armendares S, Cortes Gallegos V, Cervantes C, Bedolla N, et al. Familial true hermaphroditism in three siblings: plasma hormonal profle and in vitro steroid biosynthesis in gonadal structures. J Clin Endocrinol Metab 1976;42:653-660.
8. Vilain E. The genetics of ovotesticular disorders of sex development. Adv Exp Med Biol 2011;707:105-106.
9. Damiani D, Fellous M, McElreavey K, Barbaux S, Barreto ES, Dichtchekenian V, et al. True hermaphroditism: clinical aspects and molecular studies in 16 cases. Eur J Endocrinol 1997;136:201-204.
10. Hungerford DA, Donnelly AJ. The chromosome constitution of a human phenotypic intersex. Am J Hum Genet 1959;11:215-236.
11. Ceylan K, Algun E, Gunes M, Gonulalan H. True hermaphroditism presenting as an inguinal hernia. Int Braz J Urol 2007;33:72-73.
12. Verkauskas G, Jaubert F, Lortat-Jacob S, Malan V, Thibaud E, Nihoul-Fekete C. The long-term followup of 33 cases of true hermaphroditism: a 40-year experience with conservative gonadal surgery. J Urol 2007;177:726-731.
13. Grumbach MM, Hughes IA, Conte FA. Disorders of sex differentiation. In: Larsen PR, Kronenberg HM, Melmed S, Polonsky KS, editors. William's text book of endocrinology. Philadelphia: Saunders; 2003.p.842-1002.
14. Yordam N, Alikasifoglu A, Kandemir N, Caglar M, Balci S. True hermaphroditism: clinical features, genetic variants and gonadal histology. J Pediatr Endocrinol Metab 2001;14:421-427.
15. Berger-Zaslav AL, Mehta L, Jacob J, Mercado T, Gadi I, Tepperberg JH, et al. Ovotesticular disorder of sexual development (true hermaphroditism). Urology 2009;73:293-296.