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Volumn 33, Issue 11, 2012, Pages 1395-1400

Pharmacokinetics and pharmacodynamics of single and multiple doses of prasugrel in healthy native Chinese subjects

Author keywords

dose regimen; healthy Chinese subject; pharmacodynamics; pharmacokinetics; platelet aggregation; Prasugrel

Indexed keywords

DRUG METABOLITE; PRASUGREL; R 138727; UNCLASSIFIED DRUG;

EID: 84868531128     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2012.120     Document Type: Article
Times cited : (16)

References (10)
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    • Population pharmacokinetics and pharamcodynamics of prasugrel and clopidogrel in aspirin-treated patients with stable coronary artery disease
    • Ernest CS II, Small DS, Rohatagi S, Salazar DE, Wallentin L, Winters KJ, et al. Population pharmacokinetics and pharamcodynamics of prasugrel and clopidogrel in aspirin-treated patients with stable coronary artery disease. J Pharmacokinet Pharmacodyn 2008; 35:593-618.
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    • Ernest, C.S.I.I.1    Small, D.S.2    Rohatagi, S.3    Salazar, D.E.4    Wallentin, L.5    Winters, K.J.6
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    • Pharmacodynamics and pharmacokinetics of single doses of prasugrel 30 mg and clopidogrel 300 mg in healthy chinese and white volunteers: An open-label trial
    • Small DS, Payne CD, Kothare P, Yuen E, Natanegara F, Teng Loh M, et al. Pharmacodynamics and pharmacokinetics of single doses of prasugrel 30 mg and clopidogrel 300 mg in healthy Chinese and white volunteers: an open-label trial. Clin Ther 2010; 32:365-79.
    • (2010) Clin Ther , vol.32 , pp. 365-379
    • Small, D.S.1    Payne, C.D.2    Kothare, P.3    Yuen, E.4    Natanegara, F.5    Teng Loh, M.6
  • 6
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    • The pharmacokinetics and pharmacodynamics of prasugrel in healthy Chinese, Japanese, and Korean subjects compared with healthy Caucasian subjects
    • Small DS, Kothare P, Yuen E, Lachno DR, Li YG, Winters KJ, et al. The pharmacokinetics and pharmacodynamics of prasugrel in healthy Chinese, Japanese, and Korean subjects compared with healthy Caucasian subjects. Eur J Clin Pharmacol 2010; 66:127-35.
    • (2010) Eur J Clin Pharmacol , vol.66 , pp. 127-135
    • Small, D.S.1    Kothare, P.2    Yuen, E.3    Lachno, D.R.4    Li, Y.G.5    Winters, K.J.6
  • 7
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    • Integrated analysis of pharmacokinetic data across multiple clinical pharmacology studies of prasugrel, a new thienopyridine antiplatelet agent
    • Small DS, Li YG, Ernest CS II, April JH, Farid NA, Payne CD, et al. Integrated analysis of pharmacokinetic data across multiple clinical pharmacology studies of prasugrel, a new thienopyridine antiplatelet agent. J Clin Pharmacol 2011; 51:321-32.
    • (2011) J Clin Pharmacol , vol.51 , pp. 321-332
    • Small, D.S.1    Li, Y.G.2    Ernest, C.S.I.I.3    April, J.H.4    Farid, N.A.5    Payne, C.D.6
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    • Determination of the active and inactive metabolites of prasugrel in human plasma by liquid chromatography/tandem mass spectrometry
    • Farid NA, McIntosh M, Garofolo F, Wong E, Shwajch A, Kennedy M, et al. Determination of the active and inactive metabolites of prasugrel in human plasma by liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom 2007; 21:169-79.
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    • Common polymorphism of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel
    • Brandt JT, Close SL, Iturria SJ, Payne CD, Farid NA, Ernest CS II, et al. Common polymorphism of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel. J Thromb Haemost 2007; 5:2429-36.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.