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Volumn 33, Issue 11, 2012, Pages 1395-1400
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Pharmacokinetics and pharmacodynamics of single and multiple doses of prasugrel in healthy native Chinese subjects
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Author keywords
dose regimen; healthy Chinese subject; pharmacodynamics; pharmacokinetics; platelet aggregation; Prasugrel
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Indexed keywords
DRUG METABOLITE;
PRASUGREL;
R 138727;
UNCLASSIFIED DRUG;
ADULT;
ANTICOAGULATION;
AREA UNDER THE CURVE;
ARTICLE;
BLOOD SAMPLING;
BODY WEIGHT;
CELL ASSAY;
CHINESE;
CONTROLLED STUDY;
DOSE RESPONSE;
DRUG BLOOD LEVEL;
DRUG DOSE COMPARISON;
DRUG ERUPTION;
DRUG TOLERABILITY;
DRUG WITHDRAWAL;
ECCHYMOSIS;
FEMALE;
HUMAN;
HUMAN EXPERIMENT;
LIQUID CHROMATOGRAPHY;
LOADING DRUG DOSE;
MAINTENANCE DRUG DOSE;
MALE;
MASS SPECTROMETRY;
MAXIMUM PLASMA CONCENTRATION;
NORMAL HUMAN;
OPEN STUDY;
PHARMACODYNAMICS;
PHARMACOKINETICS;
SINGLE DRUG DOSE;
THROMBOCYTE AGGREGATION INHIBITION;
TIME TO MAXIMUM PLASMA CONCENTRATION;
ADULT;
AREA UNDER CURVE;
ASIAN CONTINENTAL ANCESTRY GROUP;
CHINA;
CHROMATOGRAPHY, LIQUID;
DOSE-RESPONSE RELATIONSHIP, DRUG;
DRUG ADMINISTRATION SCHEDULE;
FEMALE;
HUMANS;
MALE;
PIPERAZINES;
PLATELET AGGREGATION;
PLATELET AGGREGATION INHIBITORS;
PURINERGIC P2Y RECEPTOR ANTAGONISTS;
TANDEM MASS SPECTROMETRY;
THIOPHENES;
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EID: 84868531128
PISSN: 16714083
EISSN: 17457254
Source Type: Journal
DOI: 10.1038/aps.2012.120 Document Type: Article |
Times cited : (16)
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References (10)
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