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Volumn 34, Issue 3, 2012, Pages 297-299

Pharmacodynamic effects of EV-077: Results of an in vitro pilot investigation in healthy volunteers

Author keywords

[No Author keywords available]

Indexed keywords

EV 077; THROMBOXANE A2 RECEPTOR; THROMBOXANE SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 84868477095     PISSN: 09295305     EISSN: 1573742X     Source Type: Journal    
DOI: 10.1007/s11239-012-0795-6     Document Type: Article
Times cited : (7)

References (13)
  • 2
    • 0018045665 scopus 로고
    • Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin
    • Moncada S, Vane JR (1978) Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin. Pharmacol Rev 30:293-331
    • (1978) Pharmacol Rev , vol.30 , pp. 293-331
    • Moncada, S.1    Vane, J.R.2
  • 3
  • 5
    • 70349204630 scopus 로고    scopus 로고
    • Effects of pharmaceutical interventions targeting thromboxane receptors and thromboxane synthase in cardiovascular and renal diseases
    • Sakariassen KS, Alberts P, Fontana P, Mann J, Bounameaux H, Sorensen AS (2009) Effects of pharmaceutical interventions targeting thromboxane receptors and thromboxane synthase in cardiovascular and renal diseases. Fut Cardiol 5:479-493
    • (2009) Fut Cardiol , vol.5 , pp. 479-493
    • Sakariassen, K.S.1    Alberts, P.2    Fontana, P.3    Mann, J.4    Bounameaux, H.5    Sorensen, A.S.6
  • 6
    • 54049129639 scopus 로고    scopus 로고
    • Prostanoid and isoprostanoid pathways in atherogenesis
    • Pratico D (2008) Prostanoid and isoprostanoid pathways in atherogenesis. Atherosclerosis 201:8-16
    • (2008) Atherosclerosis , vol.201 , pp. 8-16
    • Pratico, D.1
  • 7
    • 80053408596 scopus 로고    scopus 로고
    • The dual thromboxane receptor antagonist and thromboxane synthase inhibitor EV-077 is a more potent inhibitor of platelet function than aspirin
    • Fontana P, Alberts P, Sakariassen KS, Bounameaux H, Meyer JP, Sorensen AS (2011) The dual thromboxane receptor antagonist and thromboxane synthase inhibitor EV-077 is a more potent inhibitor of platelet function than aspirin. J Thromb Haemost 9:2109-2111
    • (2011) J Thromb Haemost , vol.9 , pp. 2109-2111
    • Fontana, P.1    Alberts, P.2    Sakariassen, K.S.3    Bounameaux, H.4    Meyer, J.P.5    Sorensen, A.S.6
  • 8
    • 0024588409 scopus 로고
    • Measurements of platelet interaction with components of the vessel wall in flowing blood
    • Sakariassen KS, Muggli R, Baumgartner HR (1989) Measurements of platelet interaction with components of the vessel wall in flowing blood. Methods Enzymol 169:37-70
    • (1989) Methods Enzymol , vol.169 , pp. 37-70
    • Sakariassen, K.S.1    Muggli, R.2    Baumgartner, H.R.3
  • 9
    • 79958088303 scopus 로고    scopus 로고
    • Antiplatelet drug therapy: Role of pharmacodynamic and genetic testing
    • Tello-Montoliu A, Ueno M, Angiolillo DJ (2011) Antiplatelet drug therapy: role of pharmacodynamic and genetic testing. Fut Cardiol 7:381-402
    • (2011) Fut Cardiol , vol.7 , pp. 381-402
    • Tello-Montoliu, A.1    Ueno, M.2    Angiolillo, D.J.3
  • 10
    • 58249142825 scopus 로고    scopus 로고
    • Variability in responsiveness to oral antiplatelet therapy
    • Angiolillo DJ (2009) Variability in responsiveness to oral antiplatelet therapy. Am J Cardiol 103:27A-34A
    • (2009) Am J Cardiol , vol.103
    • Angiolillo, D.J.1
  • 11
  • 12
    • 0033925020 scopus 로고    scopus 로고
    • The thromboxane receptor antagonist S18886 but not aspirin inhibits atherogenesis in apo E-deficient mice: Evidence that eicosanoids other than thromboxane contribute to atherosclerosis
    • Cayatte AJ, Du Y, Oliver-Krasinski J, Lavielle G, Verbeuren TJ, Cohen RA (2000) The thromboxane receptor antagonist S18886 but not aspirin inhibits atherogenesis in apo E-deficient mice: evidence that eicosanoids other than thromboxane contribute to atherosclerosis. Arterioscler Thromb Vasc Biol 20:1724-1728
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1724-1728
    • Cayatte, A.J.1    Du, Y.2    Oliver-Krasinski, J.3    Lavielle, G.4    Verbeuren, T.J.5    Cohen, R.A.6
  • 13
    • 0347985760 scopus 로고    scopus 로고
    • Costimulation of the Gi-coupled ADP receptor and the Gq-coupled TXA2 receptor is required for ERK2 activation in collagen-induced platelet aggregation
    • Roger S, Pawlowski M, Habib A, Jandrot-Perrus M, Rosa JP, Bryckaert M (2004) Costimulation of the Gi-coupled ADP receptor and the Gq-coupled TXA2 receptor is required for ERK2 activation in collagen-induced platelet aggregation. FEBS Lett 556:227-235
    • (2004) FEBS Lett , vol.556 , pp. 227-235
    • Roger, S.1    Pawlowski, M.2    Habib, A.3    Jandrot-Perrus, M.4    Rosa, J.P.5    Bryckaert, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.