Oral mucositis in pediatric and adolescent patients undergoing chemotherapy: The impact of symptoms on quality of life

Supportive Care in Cancer

Volumn 20, Issue 10, 2012, Pages 2335-2342

  Cheng, Karis Kin Fong ^a   Lee, Vincent ^b   Li, Chak Ho ^c   Yuen, Hui Leung ^d   Epstein, Joel B ^e,f  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c TUEN MUN HOSPITAL   (Hong Kong)

^d QUEEN ELIZABETH HOSPITAL   (Hong Kong)

^e CEDARS SINAI MEDICAL CENTER   (United States)

^f CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

Chemotherapy; Pediatric and adolescent patients; Quality of life; Severe oral mucositis; Symptoms burden

Indexed keywords

ANTINEOPLASTIC AGENT; CYTARABINE; DOXORUBICIN; ETOPOSIDE; METHOTREXATE;

ADOLESCENT; ADULT; AREA UNDER THE CURVE; ARTICLE; CANCER CHEMOTHERAPY; CANCER PATIENT; CHILD; DISEASE SEVERITY; DISTRESS SYNDROME; DRINKING; EATING; FEMALE; HEMATOLOGIC MALIGNANCY; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; MORBIDITY; MULTICENTER STUDY; ORAL MUCOSITIS; PRESCHOOL CHILD; PRIORITY JOURNAL; QUALITY OF LIFE; QUESTIONNAIRE; RISK FACTOR; SCHOOL CHILD; SELF REPORT; SLEEP; SWALLOWING; SYMPTOMATOLOGY;

ADOLESCENT; ANTINEOPLASTIC AGENTS; CHILD; COST OF ILLNESS; HONG KONG; HUMANS; QUALITY OF LIFE; QUESTIONNAIRES; STOMATITIS;

EID: 84868475940     PISSN: 09414355     EISSN: 14337339     Source Type: Journal    
DOI: 10.1007/s00520-011-1343-1     Document Type: Article

References (26)

1. Anirudhan D, Bakhshi S, Xess I, Broor S, Arya LS (2008) Etiology and outcome of oral mucosal lesions in children on chemotherapy for acute lymphoblastic leukemia. Indian Ped 45(17):47-51
2. Bateman E, Keefe D (2011) Patient-reported outcomes in supportive care. Sem Oncol 38(3):358-361
3. Bellm LA, Epstein JB, Rose-Ped A, Martin P, Fuchs HJ (2000) Patient reports of complications of bone marrow transplantation. Support Care Cancer 8:33-39 (Pubitemid 30096543)
4. Borbasi S, Cameron K, Quested B, Olver I, To B, Evans D (2002) More than a sore mouth: patients' experience of oral mucositis. Oncol Nurs Forum 29(7):1051-1057
5. Cheng KKF (2007) Oral mucositis, dysfunction, and distress in patients undergoing cancer therapy. J Cl Nurs 16(11):2114-2121
6. Cheng KKF (2009) Oral mucositis: a phenomenological study of pediatric patients' and their parents' perspectives and experiences. Support Care Cancer 17(7):829-837
7. Cheng KKF, Leung SF, Liang RHS, Tai JWM, Yeung RMW, Thompson DR (2009) A patient-reported outcome instrument to assess the impact of oropharyngeal mucositis on health-related quality of life: a longitudinal psychometric evaluation. Support Care Cancer 17(4):389-398
8. Cheng KKF, Leung SF, Liang RHS, Tai JWM, Yeung RMW, Thompson DR (2010) Severe oral mucositis associated with cancer therapy: impact on oral functional status and quality of life. Support Care Cancer 18(11):1477-1485
9. Cheng KKF, Lee V, Li CH, Goggins W, Thompson DR, Yuen HL, Epstein JB (2011) Incidence and risk factors of oral mucositis in paediatric and adolescent patients undergoing chemotherapy. Oral Oncol 47(3):153-162
10. Cruz LB, Ribeiro AS, Rech A, Rosa LG, Castro CG Jr, Brunetto AL (2007) Influence of low-energy laser in the prevention of oral mucositis in children with cancer receiving chemotherapy. Ped Blood Cancer 48(4):435-440 (Pubitemid 46340110)
11. Dodd MJ, Dibble S, Miaskowski C (2001) A comparison of the affective state and quality of life of chemotherapy patients who do and do not develop chemotherapy-induced oral mucositis. J Pain Symptom Manage 21:498-505 (Pubitemid 32492936)
12. Elting LS, Keefe DM, Sonis ST, Garden AS, Spijkervet FK, Barasch A, Tishler RB, Canty TP, Kudrimoti MK, Vera-Llonch M, Burden of Illness Head and Neck Writing Committee (2008) Patient-reported measurements of oral mucositis in head and neck cancer patients treated with radiotherapy with or without chemotherapy: demonstration of increased frequency, severity, resistance to palliation, and impact on quality of life. Cancer 113(10):2704-2713
13. Epstein JB, Beaumont JL,Gwede CK (2007) Longitudinal evaluation of the oral mucositis weekly questionnaire - head and neck cancer: a patient-reported outcomes questionnaire. Cancer 109:1914-1922 (Pubitemid 46668558)
14. Figliolia SL, Oliveira DT, Pereira MC, Lauris JR, Maurício AR, Oliveira DT, Mello de Andrea ML (2008) Oral mucositis in acute lymphoblastic leukaemia: analysis of 169 paediatric patients. Oral Disease 14:761-766
15. Green R, Horn H, Erickson JM (2010) Eating experiences of children and adolescents with chemotherapy-related nausea and mucositis. J Ped Oncol Nurs 27(4):209-216
16. Isitt J, Murphy BA, Beaumont JL, Garden AS, Gwede CK, Trotti A, Meredith RF, Epstein JB, Le Q, Brizel DM, Bellm LA,Wells N, Cella D (2006) Oral mucositis-related morbidity and resource utilization in a prospective study of head and neck cancer patients. J Support Oncol 5(4):54-55
17. Kushner JA, Lawrence HP, Kiss TL (2008) Development and validation of a Patient-Reported Oral Mucositis Symptom (PROMS) Scale. JCDA 74(1):59a-59j
18. Otmani N, Alami R, Hessissen L, Mokhtari A, Soulaymani A, Khattab M (2011) Determinants of severe oral mucositis in paediatric cancer patients: a prospective study. Int J Paed Dent 21(3):210- 216
19. Redeker NS, Lev EL, Ruggiero J (2000) Insomnia, fatigue, anxiety, depression, and quality of life of cancer patients undergoing chemotherapy. Sch Inq NursPractice 14(4):275-290
20. Rosenthal DI, Mendoza TR, Chambers MS (2008) The M.D. Anderson Symptom Inventory - head and neck module, a patient-reported outcome instrument, accurately predicts the severity of radiation-induced mucositis. Int J Radiat Oncol Biol Phys 72:1355-1361
21. Sonis S, Clark J (1991) Prevention and management of oral mucositis induced by antineoplastic therapy. Oncol 5:11-17
22. Sung L, Tomlinson GA, Greenberg ML, Koren G, Judd P, Ota S, Feldman BM (2007) Serial controlled N-of-1 trials of topical vitamin E as prophylaxis for chemotherapy-induced oral mucositis in paediatric patients. Eur J Cancer 43:1269-1275 (Pubitemid 46720244)
23. Stiff PJ, Erder H, Bensinger WI, Emmanouilides C, Gentile T, Isitt J, Lu ZJ, Spielberger R (2006) Reliability and validity of a patient self-administrated daily questionnaire to assess impact of oral mucositis on pain and daily functioning in patients undergoing autologous hematopoietic stem cell transplantation. Bone Marrow Transplant 37(4):393-401 (Pubitemid 43250474)
24. Theobald DE (2004) Cancer pain, fatigue, distress, and insomnia in cancer patients. Cl Cornerstone 6:S15-S21 (Pubitemid 40468476)
25. Tomlinson D, EthierMC, Judd P, Doyle J, Gassas A, Naqvi A, Sung L (2011) Reliability and construct validity of the oral mucositis daily questionnaire in children with cancer. Eur J Cancer 47(3):383-388
26. White MC, Hommers C, Parry S, Stoddart PA (2011) Pain management in 100 episodes of severe mucositis in children. Ped Anesthesia 21:411-416