Nucleotide excision repair gene subunit XPD is highly expressed in cervical squamous cell carcinoma

Pathology and Oncology Research

Volumn 18, Issue 4, 2012, Pages 969-975

  Ye, Feng ^a   Jiao, Jie ^a   Zhou, Caiyun ^a   Cheng, Qi ^a   Chen, Huaizeng ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Cervical squamous cell carcinoma; Nucleotide excision repair; XPD

Indexed keywords

BETA ACTIN; MESSENGER RNA; XERODERMA PIGMENTOSUM GROUP D PROTEIN;

ADULT; AGE; ARTICLE; CANCER STAGING; CARCINOGENESIS; CLINICAL FEATURE; CONTROLLED STUDY; CYTOPLASM; EXCISION REPAIR; FEMALE; GENE; GENE ACTIVITY; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE LOCATION; GENE OVEREXPRESSION; GENETIC ASSOCIATION; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; OUTCOME ASSESSMENT; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM; STROMA; TUMOR VOLUME; UTERINE CERVIX CARCINOMA; XERODERMA PIGMENTOSUM D GENE;

CARCINOMA, SQUAMOUS CELL; DNA REPAIR; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; STATISTICS, NONPARAMETRIC; UTERINE CERVICAL NEOPLASMS; XERODERMA PIGMENTOSUM GROUP D PROTEIN;

EID: 84868455085     PISSN: 12194956     EISSN: 15322807     Source Type: Journal    
DOI: 10.1007/s12253-012-9527-7     Document Type: Article

References (23)

1. Wang J, Lv XW, Shi JP et al (2007) Mechanisms involved in ceramide-induced cell cycle arrest in human hepatocarcinoma cells. World J Gastroenterol 13:1129-1134
2. Wang Y, Huang B, Edelmann L et al (2010) Genes essential for cell viability that are linked to tumor suppressor genes play a role in cancer susceptibility. Cell Cycle 9:3144-3145
3. Falik-Zaccai TC, Keren Z, Slor H (2009) The Versatile DNA Nucleotide Excision Repair (NER) and Its Medical Significance. Pediatr Endocrinol Rev 7:117-122
4. Li X, Urwyler O, Suter B (2010) Drosophila Xpd regulates Cdk7 localization, mitotic kinase activity, spindle dynamics, and chromosome segregation. PLoS Genet 6:e1000876
5. Aloyz R, Xu ZY, Bello V et al (2002) Regulation of cisplatin resistance and homologous recombinational repair by the TFIIH subunit XPD. Cancer Res 62:5457-5462
6. Chen J, Suter B (2003) Xpd, a structural bridge and a functional link. Cell Cycle 2:503-506
7. Chen J, Larochelle S, Li X et al (2003) Xpd/Ercc2 regulates CAK activity and mitotic progression. Nature 424:228-232
8. He X, Ye F, Zhang J et al (2008) Susceptibility of XRCC3, XPD, and XPG genetic variants to cervical carcinoma. Pathobiology 75:356-363
9. Tavana O, Benjamin CL, Puebla-Osorio N et al (2010) Absence of p53-dependent apoptosis leads to UV radiation hypersensitivity, enhanced immunosuppression and cellular senescence. Cell Cycle 9:3328-3336
10. Singh RP, Agarwal R (2006) Natural flavonoids targeting deregulated cell cycle progression in cancer cells. Curr Drug Targets 7:345-354
11. Marchisio M, Bertagnolo V, Lanuti P et al (2006) Nuclear protein kinase C-delta: a possible check-point of cell cycle progression. Int J Immunopathol Pharmacol 19:287-291
12. Mydlikova Z, Gursky J, Pirsel M (2010) Transcription factor IIH - the protein complex with multiple functions. Neoplasma 57:287-290
13. Zhovmer A, Oksenych V, Coin F (2010) Two sides of the same coin: TFIIH complexes in transcription and DNA repair. Scientific World Journal 10:633-643
14. Zurita M, Merino C (2003) The transcriptional complexity of the TFIIH complex. Trends in Genetics 19:578-584
15. Oksenych V, de Jesus BB, Zhovmer A et al (2009) Molecular insights into the recruitment of TFIIH to sites of DNA damage. Embo J 28:2971-2980
16. Jaitovich-Groisman I, Benlimame N, Slagle BL et al (2001) Transcriptional regulation of the TFIIH transcription repair components XPB and XPD by the hepatitis B virus x protein in liver cells and transgenic liver tissue. J Bio Chem 276:14124-14132
17. Oksenych V, Coin F (2010) The long unwinding road: XPB and XPD helicases in damaged DNA opening. Cell Cycle 9:90-96
18. Gao W, Romkes M, Zhong S et al (2010) Genetic polymorphisms in the DNA repair genes XPD and XRCC1, p53 gene mutations and bladder cancer risk. Oncol Rep 24:257-262
19. Sturgis EM, Zheng R, Li L et al (2000) XPD/ERCC2 polymorphisms and risk of head and neck cancer: a case-control analysis. Carcinogenesis 21:2219-2223
20. Butkiewicz D, Rusin M, Enewold L et al (2001) Genetic polymorphisms in DNA repair genes and risk of lung cancer. Carcinogenesis 22:593-597
21. Vogel U, Hedayati M, Dybdahl M et al (2001) Polymorphisms of the DNA repair gene XPD: correlations with risk of basal cell carcinoma revisited. Carcinogenesis 22:899-904
22. Long XD, Ma Y, Zhou YF et al (2009) XPD codon 312 and 751 polymorphisms, and AFB1 exposure, and hepatocellular carcinoma risk. BMC Cancer 9:400
23. Aboussekhra A, Biggerstaff M, Shivji MK et al (1995) Mammalian DNA nucleotide excision repair reconstituted with purified protein components. Cell 80:859-868