Decreased expression of SOX7 is correlated with poor prognosis in lung adenocarcinoma patients

Pathology and Oncology Research

Volumn 18, Issue 4, 2012, Pages 1039-1045

  Li, Bing ^a,b   Ge, Zhiping ^b   Song, Shipeng ^b   Zhang, Shengbin ^b   Yan, Hong ^c   Huang, Boyun ^a   Zhang, Yangde ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b INNER MONGOLIA MEDICAL COLLEGE   (China)

^c BAOTOU MEDICAL COLLEGE   (China)

Author keywords

Immunohistochemistry; Lung adenocarcinoma; Prognosis; Quantitative real time reverse transcription polymerase chain reaction; SOX7

Indexed keywords

MESSENGER RNA; TRANSCRIPTION FACTOR SOX7;

ADULT; ARTICLE; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; CONTROLLED STUDY; DISEASE FREE SURVIVAL; DOWN REGULATION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG ADENOCARCINOMA; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURVIVAL RATE; TUMOR DIFFERENTIATION;

ADENOCARCINOMA; AGED; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG NEOPLASMS; MALE; MIDDLE AGED; PROGNOSIS; REAL-TIME POLYMERASE CHAIN REACTION; SOXF TRANSCRIPTION FACTORS; SURVIVAL ANALYSIS;

EID: 84868449650     PISSN: 12194956     EISSN: 15322807     Source Type: Journal    
DOI: 10.1007/s12253-012-9542-8     Document Type: Article

References (22)

1. Okamoto J, Kratz JR, Hirata T, Mikami I, Raz D, Segal M, Chen Z, Zhou HM, Pham P, Li H, Beltran A, Ray MR, Koizumi K, Shimizu K, Jablons D, He B (2011) Downregulation of EMX2 is associated with clinical outcomes in lung adenocarcinoma patients. Clin Lung Cancer 12:237-044
2. Travis WD, Brambilla E, Muller-Hermelink HK, Harris CC (2004) World Health Organization International Histological Classification of Tumours. Pathology and genetics of tumors of the lung, pleura, thymus and heart. IARC Press, Lyon
3. Travis WD, Brambilla E, Noguchi M, Nicholson AG, Geisinger KR, Yatabe Y, Beer DG, Powell CA, Riely GJ, Van Schil PE, Garg K, Austin JH, Asamura H, Rusch VW, Hirsch FR, Scagliotti G, Mitsudomi T, Huber RM, Ishikawa Y, Jett J, Sanchez-Cespedes M, Sculier JP, Takahashi T, Tsuboi M, Vansteenkiste J, Wistuba I, Yang PC, Aberle D, Brambilla C, Flieder D, Franklin W, Gazdar A, Gould M, Hasleton P, Henderson D, Johnson B, Johnson D, Kerr K, Kuriyama K, Lee JS,Miller VA, Petersen I, Roggli V, Rosell R, Saijo N, Thunnissen E, Tsao M, Yankelewitz D (2011) International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma. J Thorac Oncol 6:244-85
4. Katoh Y, Katoh M (2005) Comparative genomics on SOX2 orthologs. Oncol Rep 14:797-800
5. Hosking BM, Wyeth JR, Pennisi DJ, Wang SC, Koopman P, Muscat GE (2001) Cloning and functional analysis of the Sryrelated HMG box gene, Sox18. Gene 262:239-47
6. Herpers R, van de Kamp E, Duckers HJ (2008) Schulte-Merker: redundant roles for sox7 and sox18 in arteriovenous specification in zebrafish. Circ Res 102:12-15
7. Cermenati S,Moleri S, Cimbro S, Corti P, Del Giacco L, Amodeo R, Dejana E, Koopman P, Cotelli F, Beltrame M (2008) Sox18 and Sox7 play redundant roles in vascular development. Blood 111:2657-66
8. Gandillet A, Serrano AG, Pearson S, Lie-A-Ling M, Lacaud G, Kouskoff V (2009) Sox7-sustained expression alters the balance between proliferation and differentiation of hematopoietic progenitors at the onset of blood specification. Blood 114:4813-22
9. Katoh M (2002) Expression of human SOX7 in normal tissues and tumors. Int J Mol Med 9:363-8
10. Zhang Y, Huang S, Dong W, Li L, Feng Y, Pan L, Han Z, Wang X, Ren G, Su D, Huang B, Lu J (2009) SOX7, down-regulated in colorectal cancer, induces apoptosis and inhibits proliferation of colorectal cancer cells. Cancer Lett 277:29-37
11. Guo L, Zhong D, Lau S, Liu X, Dong XY, Sun X, Yang VW, Vertino PM, Moreno CS, Varma V, Dong JT, Zhou W (2008) Sox7 is an independent checkpoint for beta-catenin function in prostate and colon epithelial cells. Mol Cancer Res 6:1421-30
12. Gong YD, Dong MS, Lee SB, Kim N, Bae MS, Kang NS (2011) A novel 3-arylethynyl-substituted pyrido[2,3,-b]pyrazine derivatives and pharmacophore model as Wnt2/β-catenin pathway inhibitors in non-small-cell lung cancer cell lines. Bioorg Med Chem 19:5639-47
13. Pacheco-Pinedo EC, Durham AC, Stewart KM, Goss AM, Lu MM, Demayo FJ, Morrisey EE (2011) Wnt/β-catenin signaling accelerates mouse lung tumorigenesis by imposing an embryonic distal progenitor phenotype on lung epithelium. J Clin Invest 121:1935-45
14. Xu X, Sun PL, Li JZ, Jheon S, Lee CT, Chung JH (2011) Aberrant Wnt1/β-catenin expression is an independent poor prognostic marker of non-small cell lung cancer after surgery. J Thorac Oncol 6:716-24
15. Teng Y, Wang X, Wang Y, Ma D (2010) Wnt/beta-catenin signaling regulates cancer stem cells in lung cancer A549 cells. Biochem Biophys Res Commun 392:373-9
16. Takash W, Canizares J, Bonneaud N, Poulat F, Mattei MG, Jay P, Berta P (2001) SOX7 transcription factor: sequence, chromosomal localisation, expression, transactivation and interference with Wnt signalling. Nucleic Acids Res 29:4274-83
17. Kormish JD, Sinner D, Zorn AM (2010) Interactions between SOX factors and Wnt/beta-catenin signaling in development and disease. Dev Dyn 239:56-68
18. Ding D, Xu H, Liang Q, Xu L, Zhao Y, Wang Y (2011) Overexpression of Sox2 in C3H10T1/2 cells inhibits osteoblast differentiation through Wnt and MAPK signalling pathways. Int Orthop. In press
19. Xiang R, Liao D, Cheng T, Zhou H, Shi Q, Chuang TS, Markowitz D, Reisfeld RA, Luo Y (2011) Downregulation of transcription factor SOX2 in cancer stem cells suppresses growth and metastasis of lung cancer. Br J Cancer 104:1410-7
20. Titulaer MJ, Klooster R, Potman M, Sabater L, Graus F, Hegeman IM, Thijssen PE, Wirtz PW, Twijnstra A, Smitt PA, van der Maarel SM, Verschuuren JJ (2009) SOX antibodies in small-cell lung cancer and Lambert-Eaton myasthenic syndrome: frequency and relation with survival. J Clin Oncol 27:4260-7
21. Vural B, Chen LC, Saip P, Chen YT, Ustuner Z, Gonen M, Simpson AJ, Old LJ, Ozbek U, Gure AO (2005) Frequency of SOX Group B (SOX1, 2, 3) and ZIC2 antibodies in Turkish patients with small cell lung carcinoma and their correlation with clinical parameters. Cancer 103:2575-83
22. Friedman RS, Bangur CS, Zasloff EJ, Fan L, Wang T,Watanabe Y, Kalos M (2004) Molecular and immunological evaluation of the transcription factor SOX-4 as a lung tumor vaccine antigen. J Immunol 172:3319-27