The BRAF-V600E mutation in hematological malignancies: A new player in hairy cell leukemia and Langerhans cell histiocytosis

Leukemia and Lymphoma

Volumn 53, Issue 12, 2012, Pages 2339-2340

  Tadmor, Tamar ^a   Tiacci, Enrico ^b   Falini, Brunangelo ^b   Polliack, Aaron ^c  

^a BNAI ZION MEDICAL CENTER   (Israel)

^b UNIVERSITY OF PERUGIA   (Italy)

^c HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; B RAF KINASE INHIBITOR; BRAF V600E PROTEIN; UNCLASSIFIED DRUG;

ACUTE MYELOBLASTIC LEUKEMIA; COHORT ANALYSIS; GENE MUTATION; HAIRY CELL LEUKEMIA; HUMAN; HYPEREOSINOPHILIC SYNDROME; LANGERHANS CELL HISTIOCYTOSIS; MULTIPLE MYELOMA; MYELODYSPLASTIC SYNDROME; MYELOID LEUKEMIA; MYELOID METAPLASIA; MYELOPROLIFERATIVE NEOPLASM; NOTE; POLYCYTHEMIA VERA; PRIORITY JOURNAL; SYSTEMIC MASTOCYTOSIS; THROMBOCYTOSIS;

FEMALE; HEMATOLOGIC NEOPLASMS; HUMANS; LEUKEMIA, HAIRY CELL; MALE; MUTATION; MYELOID CELLS; NEOPLASMS; PROTO-ONCOGENE PROTEINS B-RAF;

EID: 84868362541     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.3109/10428194.2012.706289     Document Type: Note

References (19)

1. Davies H, Bignell GR, Cox C, et al. M utations of the BRAF gene in human cancer. Nature 2002; 417: 949-954. (Pubitemid 34716871)
2. Brose MS, Volpe P, Feldman M, et al. BRAF and RAS mutations in human lung cancer and melanoma. Cancer Res 2002; 62: 6997-7000. (Pubitemid 35424092)
3. Cohen Y, Xing M, Mambo E, et al. BRAF mutation in papillary thyroid carcinoma. J Natl Cancer Inst 2003; 95: 625-627. (Pubitemid 36553510)
4. Kobayashi M, Sonobe M, Takahashi T, et al. C linical significance of BRAF gene mutations in patients with non-small cell lung cancer. Anticancer Res 2011; 31: 4619-4623.
5. Badalian-Very G, Vergilio J-A, Degar BA, et al. Recurrent BRAF mutations in Langerhans cell histiocytosis. Blood 2010; 116: 1919-1923.
6. Tiacci E, Trifonov V, Schiavoni G, et al. BRAF Mutations in hairycell leukemia. N Engl J Med 2011; 364: 2305-2315.
7. Arcaini L, Zibellini S, Boveri E, et al. The BRAF V600E mutation in hairy cell leukemia and other mature B-cell neoplasms. Blood 2012; 119: 188-191.
8. Boyd EM, Bench AJ, van't Veer MB, et al. High resolution melting analysis for detection of BRAF exon mutations in hairy cell leukemia and other lymphoid leukemias. Br J Haematol 2011; 155: 609-612.
9. Tiacci E, Schiavoni G, Forconi F, et al. Simple genetic diagnosis of hairy cell leukemia by sensitive detection of the BRAF-V600E mutation. Blood 2012; 119: 192-195.
10. Foucar K, Falini B, Catovsky D, et al. Hairy cell leukemia. In Swerdlow S, Campo E, Harris NL, et al., editors. WHO classification of tumors of haematopoietic and lymphoid tissues. 4th ed. Lyon, France: IARC; 2008. pp 188-190.
11. Basso K, Liso A, Tiacci E, et al. Gene expression profiling of hairy cell leukemia reveals a phenotype related to memory B cells with altered expression of chemokine and adhesion receptors. J Exp Med 2004; 199: 59-68. (Pubitemid 38076478)
12. Tiacci E, Liso A, Piris M, et al. Evolving concepts in the pathogenesis of hairy-cell leukaemia. Nat Rev Cancer 2006; 6: 437-448.
13. Kitagawa Y, Brahmachary M, Tiacci E, et al. A microRNA signature specific for hairy cell leukemia and associated with modulation of the MAPK-JNK pathways. Leukemia 2012 Jun 4. [Epub ahead of print]
14. Trifa AP, Popp RA, Cucuianu A, et al. Absence of BRAF V600E mutation in a cohort of 402 patients with various chronic and acute myeloid neoplasms. Leuk Lymphoma 2012; 53: 2496-2497.
15. Ping N, Wang Q, Wang Q, et al. Absence of BRAF V600E mutation in hematologic malignancies excluding hairy-cell leukemia. Leuk Lymphoma 2012; 53: 2498-2499.
16. Pardanani A, Tefferi A. BRAF mutations in hairy-cell leukemia. N Engl J Med 2011;365:961; author reply 961-962.
17. Tiacci E, Trifnov V, Schiavoni G, et al. BRAF mutations in hairycell leukemia. N Engl J Med 2011; 364: 2305-2315.
18. Sosman JA, Kim KB, Schuchter L, et al. Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib. N Engl J Med 2012: 366: 707-714.
19. Dienstmann R, Tabernero J. BRAF as a target for cancer therapy. Anticancer Agents Med Chem 2011; 11: 285-295.