Variations in Mortality in Children Admitted with Pneumonia to Kenyan Hospitals

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Ayieko, Philip ^a   Okiro, Emelda A ^a   Edwards, Tansy ^b   Nyamai, Rachel ^c   English, Mike ^a,d  

^a KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c Ministry of Medical Services   (Kenya)

^d UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HAEMOPHILUS INFLUENZAE TYPE B VACCINE;

AGE DISTRIBUTION; ARTICLE; CHILD; CHILDHOOD MORTALITY; DISEASE SEVERITY; FEMALE; HOSPITAL; HOSPITAL ADMISSION; HUMAN; INFANT; KENYA; MAJOR CLINICAL STUDY; MALE; PNEUMONIA; PRESCHOOL CHILD; RISK FACTOR; TIME SERIES ANALYSIS; TREND STUDY;

CHILD; CHILD MORTALITY; CROSS-SECTIONAL STUDIES; FEMALE; HOSPITALIZATION; HOSPITALS; HUMANS; INFANT; KENYA; MALE; PNEUMONIA; TIME FACTORS; TREATMENT OUTCOME;

EID: 84868349857     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0047622     Document Type: Article

References (21)

1. Black RE, Cousens S, Johnson HL, Lawn JE, Rudan I, et al. (2010) Global, regional, and national causes of child mortality in 2008: a systematic analysis. Lancet 375: 1969-1987.
2. Rudan I, Tomaskovic L, Boschi-Pinto C, Campbell H, (2004) Global estimate of the incidence of clinical pneumonia among children under five years of age. Bulletin of the World Health Organization 82: 895-903.
3. Division of health management and information system. Ministry of Public health and Sanitation. Republic of Kenya (2009) Annual health sector statistics report 2008.
4. Lilford R, Pronovost P, (2010) Using hospital mortality rates to judge hospital performance: a bad idea that just won't go away. BMJ 340: c2016.
5. Park RE, Brook RH, Kosecoff J, Keesey J, Rubenstein L, et al. (1990) Explaining variations in hospital death rates. Randomness, severity of illness, quality of care. Jama 264(4): 484-490.
6. Rosenthal GE, Shah A, Way LE, Harper DL, (1998) Variations in standardized hospital mortality rates for six common medical diagnoses: implications for profiling hospital quality. Med Care 36: 955-964.
7. Sinha A, Levine O, Knoll MD, Muhib F, Lieu TA, (2007) Cost-effectiveness of pneumococcal conjugate vaccination in the prevention of child mortality: an international economic analysis. Lancet 369: 389-396.
8. Ayieko P, Ntoburi S, Wagai J, Opondo C, Opiyo N, et al. (2011) A multifaceted intervention to implement guidelines and improve admission paediatric care in Kenyan district hospitals: a cluster randomised trial. PLoS Medicine 8(4): e1001018.
9. English M, Irimu G, Wamae A, Were F, Wasunna A, et al. (2008) Health systems research in a low-income country: easier said than done. Archives of disease in childhood 93: 540-544.
10. Berkley JA, Lowe BS, Mwangi I, Williams T, Bauni E, et al. (2005) Bacteremia among children admitted to a rural hospital in Kenya. NEJM 2005 352: 39-47.
11. Cowgill KD, Ndiritu M, Nyiro J, Slack MP, Chiphatsi S, et al. (2006) Effectiveness of Haemophilus influenzae type b Conjugate vaccine introduction into routine childhood immunization in Kenya. JAMA 296: 671-678.
12. Lee K, (2009) Pneumococcal campaign foreshadows wider initiatives. The Lancet Infectious Diseases 9: 597.
13. Mwakyusa S, Wamae A, Wasunna A, Were F, Esamai F, et al. (2006) Implementation of a structured paediatric admission record for district hospitals in Kenya-results of a pilot study. BMC International Health and Human Rights 6: 9.
14. Demers AM, Morency P, Mberyo-Yaah F, Jaffar S, Blais C, et al. (2000) Risk factors for mortality among children hospitalized because of acute respiratory infections in Bangui, Central African Republic. PIDJ 19: 424-432.
15. Berkley JA, Maitland K, Mwangi I, Ngetsa C, Mwarumba S, et al. (2005) Use of clinical syndromes to target antibiotic prescribing in seriously ill children in malaria endemic area: observational study. BMJ 330: 995.
16. Newell ML, Brahmbhatt H, Ghys PD, (2004) Child mortality and HIV infection in Africa: a review. AIDS 18 (Suppl 2): S27-34.
17. Gove S, (1997) Integrated management of childhood illness by outpatient health workers: technical basis and overview. The WHO Working Group on Guidelines for Integrated Management of the Sick Child. Bulletin of the World Health Organization 75 (Suppl 1): 7-24.
18. Smyth A, Tong CY, Carty H, Hart CA, (1997) Impact of HIV on mortality from acute lower respiratory tract infection in rural Zambia. Archives of disease in childhood 77: 227-230.
19. Nokes DJ, Ngama M, Bett A, Abwao J, Munywoki P, et al. (2009) Incidence and severity of respiratory syncytial virus pneumonia in rural Kenyan children identified through hospital surveillance. Clin Infect Dis 49: 1341-1349.
20. Centers for Disease Control and Prevention (2005) Direct and indirect effects of routine vaccination of children with 7-valent pneumococcal conjugate vaccine on incidence of invasive pneumococcal disease-United States, 1998-2003. MMWR 54: 893-897.
21. English M, Scott JA, (2008) What is the future for global case management guidelines for common childhood diseases? PLoS medicine 5: e241.