Incidence of cerebral ischemic events after discontinuation of clopidogrel in patients with intracranial aneurysms treated with stent-assisted techniques

Journal of Neurosurgery

Volumn 117, Issue 5, 2012, Pages 929-933

  Rossen, James D ^b   Chalouhi, Nohra ^c   Wassef, Shafik N ^a,d,e   Thomas, Jacob ^a   Abel, Taylor J ^a   Jabbour, Pascal M ^c   Kung, David K ^a   Hasan, David M ^a  

^a UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c THOMAS JEFFERSON UNIVERSITY HOSPITAL   (United States)

^d MCGILL UNIVERSITY   (Canada)

^e MCGILL UNIVERSITY   (Canada)

Author keywords

Aspirin; Clopidogrel; Intracranial aneurysm; Ischemia; Stent; Vascular disorders

Indexed keywords

ACETYLSALICYLIC ACID; CLOPIDOGREL; TIROFIBAN;

ADULT; AGED; ANTICOAGULANT THERAPY; ARTICLE; BRAIN ISCHEMIA; CARDIOVASCULAR RISK; CLINICAL PROTOCOL; COIL EMBOLIZATION; DISEASE PREDISPOSITION; DRUG WITHDRAWAL; FEMALE; FOLLOW UP; HUMAN; INTRACRANIAL ANEURYSM; LOADING DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; NEUROLOGIC EXAMINATION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; STENT; SUBARACHNOID HEMORRHAGE; TRANSIENT ISCHEMIC ATTACK; TREATMENT DURATION; TREATMENT WITHDRAWAL;

AGED; AGED, 80 AND OVER; ASPIRIN; BRAIN ISCHEMIA; COHORT STUDIES; DRUG THERAPY, COMBINATION; EMBOLIZATION, THERAPEUTIC; FEMALE; HUMANS; INTRACRANIAL ANEURYSM; ISCHEMIC ATTACK, TRANSIENT; MALE; MIDDLE AGED; NEUROSURGICAL PROCEDURES; PLATELET AGGREGATION INHIBITORS; RETROSPECTIVE STUDIES; STENTS; STROKE; SUBARACHNOID HEMORRHAGE; TICLOPIDINE;

EID: 84868348824     PISSN: 00223085     EISSN: 19330693     Source Type: Journal    
DOI: 10.3171/2012.8.JNS12185     Document Type: Article

References (14)

1. Brott T, Bogousslavsky J: Treatment of acute ischemic stroke. N Engl J Med 343:710-722, 2000
2. Lee DH, Arat A, Morsi H, Shaltoni H, Harris JR, Mawad ME: Dual antiplatelet therapy monitoring for neurointerventional procedures using a point-of-care platelet function test: a singlecenter experience. AJNR Am J Neuroradiol 29:1389-1394, 2008
3. al: A clinical trial comparing three antithrombotic-drug regimens after coronary-artery stenting. N Engl J Med 339:1665-1671, 1998
4. Mocco J, Fargen KM, Albuquerque FC, Bendok BR, Boulos AS, Carpenter JS, et al: Delayed thrombosis or stenosis following enterprise-assisted stent-coiling: is it safe? Midterm results of the interstate collaboration of enterprise stent coiling. Neurosurgery 69:908-914, 2011
5. Moret J, Cognard C, Weill A, Castaings L, Rey A: [Reconstruction technic in the treatment of wide-neck intracranial aneurysms. Long-term angiographic and clinical results. Apropos of 56 cases.] J Neuroradiol 24:30-44, 1997 (Fr)
6. Moussa I, Oetgen M, Roubin G, Colombo A, Wang X, Iyer S, et al: Effectiveness of clopidogrel and aspirin versus ticlopidine and aspirin in preventing stent thrombosis after coronary stent implantation. Circulation 99:2364-2366, 1999
7. Moussa ID, Colombo A: Antiplatelet therapy discontinuation following drug-eluting stent placement: dangers, reasons, and management recommendations. Catheter Cardiovasc Interv 74:1047-1054, 2009
8. Piotin M, Blanc R, Spelle L, Mounayer C, Piantino R, Schmidt PJ, et al: Stent-assisted coiling of intracranial aneurysms: clinical and angiographic results in 216 consecutive aneurysms. Stroke 41:110-115, 2010
9. Riedel CH, Tietke M, Alfke K, Stingele R, Jansen O: Subacute stent thrombosis in intracranial stenting. Stroke 40:1310-1314, 2009
10. Sambu N, Warner T, Curzen N: Clopidogrel withdrawal: is there a "rebound" phenomenon? Thromb Haemost 105:211-220, 2011
11. Schömig A, Neumann FJ, Kastrati A, Schühlen H, Blasini R, Hadamitzky M, et al: A randomized comparison of antiplatelet and anticoagulant therapy after the placement of coronaryartery stents. N Engl J Med 334:1084-1089, 1996
12. Von Beckerath N, Pogatsa-Murray G, Wieczorek A, Sibbing D, Schömig A, Kastrati A: Correlation of a new point-of-care test with conventional optical aggregometry for the assessment of clopidogrel responsiveness. Thromb Haemost 95:910-911, 2006
13. Wiviott SD, Braunwald E, McCabe CH, Montalescot G, Ruzyllo W, Gottlieb S, et al: Prasugrel versus clopidogrel in patients with acute coronary syndromes. N Engl J Med 357:2001-2015, 2007
14. Yamada NK, Cross DT III, Pilgram TK, Moran CJ, Derdeyn CP, Dacey RG Jr: Effect of antiplatelet therapy on thromboembolic complications of elective coil embolization of cerebral aneurysms. AJNR Am J Neuroradiol 28:1778-1782, 2007