Early Detection and Treatment of Severe Sepsis in the Emergency Department: Identifying Barriers to Implementation of a Protocol-based Approach

Journal of Emergency Nursing

Volumn 38, Issue 6, 2012, Pages 512-517

  Burney, Mara ^a   Underwood, Joseph ^a   McEvoy, Shayna ^a   Nelson, Germaine ^a   Dzierba, Amy ^a   Kauari, Vepuka ^a   Chong, David ^a  

^a NewYork Presbyterian Hospital   (United States)

Author keywords

Barriers; Early goal directed therapy; Emergency department; Sepsis; Survey

Indexed keywords

ARTICLE; ATTITUDE TO HEALTH; CLINICAL PATHWAY; CLINICAL PRACTICE; EARLY DIAGNOSIS; EMERGENCY HEALTH SERVICE; HEALTH CARE PLANNING; HEALTH CARE SURVEY; HUMAN; NURSING; NURSING PRACTICE; SEPSIS; SEPTIC SHOCK; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; TOTAL QUALITY MANAGEMENT; UNITED STATES; UNIVERSITY HOSPITAL;

ACADEMIC MEDICAL CENTERS; CRITICAL PATHWAYS; EARLY DIAGNOSIS; EMERGENCY SERVICE, HOSPITAL; HEALTH CARE SURVEYS; HEALTH KNOWLEDGE, ATTITUDES, PRACTICE; HEALTH PLAN IMPLEMENTATION; HUMANS; NURSE'S PRACTICE PATTERNS; PHYSICIAN'S PRACTICE PATTERNS; QUALITY IMPROVEMENT; SEPSIS; SHOCK, SEPTIC; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; UNITED STATES;

EID: 84868348346     PISSN: 00991767     EISSN: 15272966     Source Type: Journal    
DOI: 10.1016/j.jen.2011.08.011     Document Type: Article

References (20)

1. Wang HE, Shapiro NI, Angus DC, Yealy DM National estimates of severe sepsis in United States emergency departments. Crit Care Med 2007, 35(8):1928-1936.
2. Melamed A, Sorvillo FJ The burden of sepsis-associated mortality in the United States from 1999-2005: an analysis of multiple cause-of-death data. Crit Care 2009, 13:R28.
3. Jacobi J Pathophysiology of sepsis. Am J Health Syst Pharm 2002, 59(suppl 1):S3-S8.
4. Rivers E, Nguyen B, Havstad S, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001, 345:1368-1377.
5. Jones AE, Focht A, Horton JM, Kline JA Prospective external validation of the clinical effectiveness of an emergency department-based early goal-directed therapy protocol for severe sepsis and septic shock. Chest 2007, 132:425-432.
6. Trzeciak S, Dellinger RP, Abate NL, et al. Translating research to clinical practice: a 1-year experience with implementing early goal-directed therapy for septic shock in the emergency department. Chest 2006, 129:225-232.
7. Dellinger RP, Carlet J, Masur H, et al. Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock. Crit Care Med 2004, 32(3):858-873.
8. Dellinger RP, Levy M, Carlet J, et al. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med 2008, 36(1):296-327.
9. Institute for Healthcare Improvement. Sepsis care enters new era Accessed October 4, 2011. http://www.ihi.org/knowledge/Pages/ImprovementStories/SepsisCareEntersNewEra.aspx.
10. Castellanos-Ortega A, Suberviola B, Garcia-Astudillo LA, et al. Impact of the Surviving Sepsis Campaign protocols on hospital length of stay and mortality in septic shock patients: results of a three-year follow-up quasi-experimental study. Crit Care Med 2010, 38(4):1036-1043.
11. Levy MM, Dellinger RP, Townsend SR, et al. The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis. Crit Care Med 2010, 38(2):367-374.
12. Jones AE, Shapiro NI, Trzeciak S, Arnold R, Claremont HA, Kline JA Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy. JAMA 2010, 303:739-746.
13. Vanzant AM, Schmelzer M Detecting and treating sepsis in the emergency department. J Emerg Nurs 2011, 37(1):47-54.
14. Carlbom DJ, Rubenfeld GD Barriers to implementing protocol-based sepsis resuscitation in the emergency department-results of a national survey. Crit Care Med 2007, 35:2525-2532.
15. Middleton P, Kelly AM, Brown J, Robertson M Agreement between arterial and central venous values for pH, bicarbonate, base access, and lactate. BMJ 2006, 23:622-624.
16. Younger J, Falk J, Rothrock S Relationship between arterial and peripheral venous lactate levels. Acad Emerg Med 1996, 3:730-734.
17. Sexton JB TeamSTEPPS Fundamentals Course: module 1. Introduction: instructor's slides Accessed October 4, 2011. http://www.ahrq.gov/teamsteppstools/instructor/fundamentals/module1/igintro.htm.
18. Aitken MA, Williams G, Harvey M, et al. Nursing considerations to complement the Surviving Sepsis Campaign guidelines. Crit Care Med 2011, 39(7):1800-1818.
19. Tromp M, Hulscher M, Bleeker-Rovers CP, et al. The role of nurses in the recognition and treatment of patients with sepsis in the emergency department: a prospective before-and-after intervention study. Int J Nurs Stud 2010, 47:1464-1473.
20. Institute for Healthcare Improvement Develop a culture of safety Accessed October 4, 2011. http://www.ihi.org/knowledge/Pages/Changes/DevelopaCultureofSafety.aspx.