Increased nasopharyngeal bacterial titers and local inflammation facilitate transmission of Streptococcus pneumoniae

mBio

Volumn 3, Issue 5, 2012, Pages

  Short, Kirsty R ^a   Reading, Patrick C ^a,b   Wang, Nancy ^a   Diavatopoulos, Dimitri A ^c   Wijburg, Odilia L ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b VICTORIAN INFECTIOUS DISEASES REFERENCE LABORATORY   (Australia)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84868340904     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.00255-12     Document Type: Article

References (30)

1. Adegbola RA, Obaro SK, Biney E, Greenwood BM. 2001. Evaluation of Binax NOW Streptococcus pneumoniae urinary antigen test inchildren ina community with a high carriage rate of pneumococcus. Pediatr. Infect. Dis. J. 20: 718-719.
2. Kadioglu A, Weiser JN, Paton JC, Andrew PW. 2008. The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease. Nat. Rev. Microbiol. 6:288-301.
3. WHO. 2003. Pneumococcal vaccines. Wkly. Epidemiol. Rec. 78:110-119.
4. Gray BM, Converse GM III, Dillon HC, Jr.1980. Epidemiologic studies of Streptococcus pneumoniaein infants: acquisition, carriage, and infection during the first 24 months of life. J. Infect. Dis. 142:923-933.
5. Levine H, et al. 2012. Transmission of Streptococcus pneumoniae in adults may occur through saliva. Epidemiol. Infect. 140:561-565.
6. Sá-Leão R, et al. 2008. High rates of transmission of and colonization by Streptococcus pneumoniae and Haemophilus influenzae within a day care center revealed in a longitudinal study. J. Clin. Microbiol. 46:225-234.
7. Yagupsky P, et al. 1998. Acquisition, carriage, and transmission of pneu-mococci with decreased antibiotic susceptibility inyoung children attending a day care facility in southern Israel. J. Infect. Dis. 177:1003-1012.
8. Gwaltney JM, Jr, Sande MA, Austrian R, Hendley JO. 1975. Spread of Streptococcus pneumoniae in families. II. Relation of transfer of S. pneu-moniae to incidence of colds and serum antibody. J. Infect. Dis. 132: 62-68.
9. Ujiie M, et al. 2010. Household transmission of pneumococcal pneumonia associated with pandemic influenza (H1N1) 2009. Nihon Kokyuki Gakkai Zasshi 48: 322-327. (In Japanese).
10. Speshock JL, Doyon-Reale N, Rabah R, Neely MN, Roberts PC. 2007. Filamentous influenza A virus infection predisposes mice to fatal septice-mia following superinfection with Streptococcus pneumoniae serotype 3. Infect. Immun. 75:3102-3111.
11. Vu HT, et al. 2011. Association between nasopharyngeal load of Streptococcus pneumoniae, viral coinfection, and radiologically confirmed pneumonia in Vietnamese children. Pediatr. Infect. Dis. J. 30:11-18.
12. Wadowsky RM, Mietzner SM, Skoner DP, Doyle WJ, Fireman P. 1995. Effect of experimental influenza A virus infection on isolation of Streptococcus pneumoniae and other aerobic bacteria from the oropharynges of allergic and nonallergic adult subjects. Infect. Immun. 63:1153-1157.
13. Diavatopoulos DA, et al. 2010. Influenza A virus facilitates Streptococcus pneumoniae transmission and disease. FASEB J. 24:1789-1798.
14. Nakamura S, Davis KM, Weiser JN. 2011. Synergistic stimulation of type I interferons during influenza virus coinfection promotes Streptococcus pneumoniae colonization in mice. J. Clin. Invest. 121:3657-3665.
15. Shivshankar P, Boyd AR, Le Saux CJ, Yeh IT, Orihuela CJ. 2011. Cellular senescence increases expression of bacterial ligands in the lungs and is positively correlated with increased susceptibility to pneumococcal pneumonia. Aging Cell 10:798-806.
16. van der Sluijs KF, et al. 2006. Involvement of the platelet-activating factor receptor in host defense against Streptococcus pneumoniae during postinfluenza pneumonia. Am. J. Physiol. Lung Cell Mol. Physiol. 290: 194-199.
17. McCullers JA, Rehg JE. 2002. Lethal synergism between influenza virus and Streptococcus pneumoniae: characterization of a mouse model and the role of platelet-activating factor receptor. J. Infect. Dis. 186:341-350.
18. McCullers JA, et al. 2010. Influenza enhances susceptibility to natural acquisition of and disease due to Streptococcus pneumoniae in ferrets. J. Infect. Dis. 202:1287-1295.
19. Trappetti C, et al. 2009. Sialic acid: a preventable signal for pneumococcal biofilm formation, colonization, and invasion of the host. J. Infect. Dis. 199:1497-1505.
20. Lu YJ, et al. 2008. Interleukin-17A mediates acquired immunity to pneu-mococcal colonization. PLoS Pathog. 4 e1000159.
21. Lowen AC, Mubareka S, Tumpey TM, García-Sastre A, Palese P. 2006. The guinea pigasatransmission model for human influenza viruses. Proc. Natl. Acad. Sci. USA 103:9988-9992.
22. Mubareka S, et al. 2009. Transmission of influenza virus via aerosols and fomites in the guinea pig model. J. Infect. Dis. 199:858-865.
23. Smith-Vaughan H, Crichton F, Beissbarth J, Morris PS, Leach AJ. 2008. Survival of pneumococcus on hands and fomites. BMC Res. Notes 1:112.
24. Matthias KA, Roche AM, Standish AJ, Shchepetov M, Weiser JN. 2008. Neutrophil-toxin interactions promote antigen delivery and mucosal clearance of Streptococcus pneumoniae. J. Immunol. 180:6246-6254.
25. Hinojosa E, Boyd AR, Orihuela CJ. 2009. Age-associated inflammation and Toll-like receptor dysfunction prime the lungs for pneumococcal pneumonia. J. Infect. Dis. 200:546-554.
26. Karlström A, Boyd KL, English BK, McCullers JA. 2009. Treatment with protein synthesis inhibitors improves outcomes of secondary bacterial pneumonia after influenza. J. Infect. Dis. 199:311-319.
27. Harford CG, Leidler V, Hara M. 1949. Effect of the lesion due to influenza virus on the resistance of mice to inhaled pneumococci. J. Exp. Med. 89:53-68.
28. Short KR, et al. 2011. Using bioluminescent imaging to investigate syn-ergism between Streptococcus pneumoniae and influenza A virus in infant mice. J. Vis. Exp.:e2357.
29. Short KR, et al. 2011. Influenza virus induces bacterial and nonbacterial otitis media. J. Infect. Dis. 204:1857-1865.
30. Fleming TJ, Fleming ML, Malek TR. 1993. Selective expression of Ly-6G on myeloid lineage cells in mouse bone marrow. RB6-8C5 MAb to granulocyte-differentiation antigen (Gr-1) detects members of the Ly-6 family. J. Immunol. 151:2399-2408.