Attenuation of Streptococcus suis virulence by the alteration of bacterial surface architecture

Scientific Reports

Volumn 2, Issue , 2012, Pages

  Feng, Youjun ^a,c   Cao, Min ^a,b   Shi, Jie ^a   Zhang, Huimin ^c   Hu, Dan ^a   Zhu, Jing ^a   Zhang, Xianyun ^a   Geng, Meiling ^a   Zheng, Feng ^a   Pan, Xiuzhen ^a   Li, Xianfu ^a   Hu, Fuquan ^b   Tang, Jiaqi ^a   Wang, Changjun ^a  

^a Research Institute for Medicine of Nanjing Command   (China)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; INTERLEUKIN 8; LYASE; N ACETYLNEURAMINATE SYNTHASE; N-ACETYLNEURAMINATE SYNTHASE; SIALIC ACID DERIVATIVE;

AMINO ACID SEQUENCE; ANIMAL; ANIMAL DISEASE; ARTICLE; BACTERIAL CAPSULE; BACTERIUM ADHERENCE; CHEMICAL STRUCTURE; GENETICS; HOST PATHOGEN INTERACTION; METABOLISM; MICROBIOLOGY; MOLECULAR GENETICS; MOUSE; MUTATION; PATHOGENICITY; PH; PHAGOCYTOSIS; SECRETION (PROCESS); STREPTOCOCCUS INFECTION; STREPTOCOCCUS SUIS; SWINE; SWINE DISEASE; TUMOR CELL LINE; VIRULENCE;

AMINO ACID SEQUENCE; ANIMALS; BACTERIAL ADHESION; BACTERIAL CAPSULES; BACTERIAL PROTEINS; CELL LINE, TUMOR; HOST-PATHOGEN INTERACTIONS; HYDROGEN-ION CONCENTRATION; INTERLEUKIN-8; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; OXO-ACID-LYASES; PHAGOCYTOSIS; SIALIC ACIDS; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS SUIS; SWINE; SWINE DISEASES; VIRULENCE;

EID: 84868274944     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep00710     Document Type: Article

References (51)

1. Weiman, S. et al. O-Acetylation of sialic acid on Group B Streptococcus inhibits neutrophil suppression and virulence. Biochem J 428, 163-8 (2010).
2. Lewis, A. L., Hensler, M. E., Varki, A. & Nizet, V. The group B streptococcal sialic acid O-acetyltransferase is encoded by neuD, a conserved component of bacterial sialic acid biosynthetic gene clusters. J Biol Chem 281, 11186-92 (2006). (Pubitemid 43855544)
3. Crocker, P. R., Paulson, J. C. & Varki, A. Siglecs and their roles in the immune system. Nat Rev Immunol 7, 255-66 (2007). (Pubitemid 46480955)
4. Angata, T. & Varki, A. Chemical diversity in the sialic acids and related alpha-keto acids: An evolutionary perspective. Chem Rev 102, 439-69 (2002). (Pubitemid 35381636)
5. Gagneux, P. & Varki, A. Evolutionary considerations in relating oligosaccharide diversity to biological function. Glycobiology 9, 747-55 (1999). (Pubitemid 29376001)
6. Lewis, A. L. et al. Innovations in host and microbial sialic acid biosynthesis revealed by phylogenomic prediction of nonulosonic acid structure. Proc Natl Acad Sci USA 106, 13552-7 (2009).
7. Hickey, T. E., Majam, G. & Guerry, P. Intracellular survival of Campylobacter jejuni in human monocytic cells and induction of apoptotic death by cytholethal distending toxin. Infect Immun 73, 5194-7 (2005). (Pubitemid 41105680)
8. Jurcisek, J. et al. Role of sialic acid and complex carbohydrate biosynthesis in biofilm formation by nontypeable Haemophilus influenzae in the chinchilla middle ear. Infect Immun 73, 3210-8 (2005). (Pubitemid 40745860)
9. Guerry, P., Ewing, C. P., Hickey, T. E., Prendergast, M. M. & Moran, A. P. Sialylation of lipooligosaccharide cores affects immunogenicity and serum resistance of Campylobacter jejuni. Infect Immun 68, 6656-62 (2000). (Pubitemid 32463367)
10. Lewis, A. L., Nizet, V. & Varki, A. Discovery and characterization of sialic acid O-acetylation in group B Streptococcus. Proc Natl Acad Sci USA 101, 11123-8 (2004). (Pubitemid 38989594)
11. Lewis, A. L. et al. NeuA sialic acid O-acetylesterase activity modulates O-acetylation of capsular polysaccharide in group B Streptococcus. J Biol Chem 282, 27562-71 (2007). (Pubitemid 47529513)
12. Severi, E., Hood, D. W. & Thomas, G. H. Sialic acid utilization by bacterial pathogens. Microbiology 153, 2817-22 (2007). (Pubitemid 47517045)
13. Liu, C. H., Lee, S. M., Vanlare, J. M., Kasper, D. L. & Mazmanian, S. K. Regulation of surface architecture by symbiotic bacteria mediates host colonization. Proc Natl Acad Sci USA 105, 3951-6 (2008). (Pubitemid 351723505)
14. Gottschalk, M., Segura, M. & Xu, J. Streptococcus suis infections in humans: the Chinese experience and the situation in North America. Anim Health Res Rev 8, 29-45 (2007).
15. Feng, Y., Zhang, H., Ma, Y. & Gao, G. F. Uncovering newly emerging variants of Streptococcus suis, an important zoonotic agent. Trends Microbiol 18, 124-31 (2010).
16. Feng, Y. et al. Recurrence of human Streptococcus suis infections in 2007: three cases of meningitis and implications that heterogeneous S. suis 2 circulates in China. Zoonoses Public Health 56, 506-14 (2009).
17. Tang, J. et al. Streptococcal toxic shock syndrome caused by Streptococcus suis serotype 2. PLoS Med 3, 0668-0676 (2006).
18. Li, M. et al. GI-type T4SS-mediated horizontal transfer of the 89K pathogenicity island in epidemic Streptococcus suis serotype 2. Mol Microbiol 79, 1670-83 (2011).
19. Li, M. et al. SalK/SalR, a two-component signal transduction system, is essential for full virulence of highly invasive Streptococcus suis serotype 2. PLoS One 3, e2080 (2008).
20. Chen, C. et al. A glimpse of streptococcal toxic shock syndrome from comparative genomics of S. suis 2 Chinese isolates. PLoS One 2, e315 (2007).
21. Cao, M. et al. Functional definition of LuxS, an autoinducer-2 (AI-2) synthase and its role in full virulence of Streptococcus suis serotype 2. J Microbiol 49, 1000-11 (2011).
22. Wang, C. et al. The involvement of sortase A in high virulence of STSS-causing Streptococcus suis serotype 2. Arch Microbiol 191, 23-33 (2009).
23. Pan, X. et al. The orphan response regulator CovR: A globally negative modulator of virulence in Streptococcus suis serotype 2. J Bacteriol 191, 2601-12 (2009).
24. Ge, J. et al. Inactivation of dipeptidyl peptidase IV attenuates the virulence of Streptococcus suis serotype 2 that causes streptococcal toxic shock syndrome. Curr Microbiol 59, 248-55 (2009).
25. Feng, Y. et al. Streptococcus suis enolase functions as a protective antigen displayed on the bacterial cell surface. J Infect Dis 200, 1583-92 (2009).
26. Feng, Y. et al. Existence and characterization of allelic variants of Sao, a newly identified surface protein from Streptococcus suis. FEMS Microbiol Lett 275, 80-8 (2007). (Pubitemid 47390090)
27. Feng, Y., Cao, M., Wu, Z., Chu, F., Ma, Y., Wang, C., Zhang, H., Pan, X., Mao, X. & Zou, Q. Streptococcus suis in Omics-Era: Where do we stand? J Bacteriol & Parasitol S2-001 (2011).
28. Gunawan, J. et al. Structural and mechanistic analysis of sialic acid synthase NeuB from Neisseria meningitidis in complex with Mn21, phosphoenolpyruvate, and N-acetylmannosaminitol. J Biol Chem 280, 3555-63 (2005). (Pubitemid 40223821)
29. Wilson, T. L. et al. A novel signature-tagged mutagenesis system for Streptococcus suis serotype 2. Vet Microbiol 122, 135-45 (2007). (Pubitemid 46613855)
30. Segura, M. A., Cléroux, P. & Gottschalk, M. Streptococcus suis and group B Streptococcus differ in their interactions with murine macrophages. FEMS Immunol. Med. Microbiol. 21, 189-195 (1998). (Pubitemid 28356840)
31. Charland, N., Kobisch, M., Martineau-Doize, B., Jacques, M. & Gottschalk, M. Role of capsular sialic acid in virulence and resistance to phagocytosis of Streptococcus suis capsular type 2. FEMS Immunol Med Microbiol 14, 195-203 (1996). (Pubitemid 26249234)
32. Arends, J. P. & Zanen, H. C. Meningitis caused by Streptococcus suis in humans. Rev Infect Dis 10, 131-7 (1988).
33. Gottschalk, M. & Segura, M. The pathogenesis of the meningitis caused by Streptococcus suis: the unresolved questions. Vet Microbiol 75, 59-71 (2000).
34. Benga, L., Goethe, R., Rohde, M. & Valentin-Weigand, P. Non-encapsulated strains reveal novel insights in invasion and survival of Streptococcus suis in epithelial cells. Cell Microbiol 6, 867-81 (2004). (Pubitemid 39162628)
35. Castaneda-Roldan, E. I. et al. Adherence of Brucella to human epithelial cells and macrophages is mediated by sialic acid residues. Cell Microbiol 6, 435-45 (2004). (Pubitemid 38488936)
36. Charland, N., Harel, J., Kobish, M., Lacasse, S. & Gottschalk, M. Streptococcus suis serotype 2 mutants deficient in capsular expression. Microbiology 144, 325-332 (1998). (Pubitemid 28067737)
37. Segura, M., Gottschalk, M. & Olivier, M. Encapsulated Streptococcus suis inhibits activation of signaling pathways involved in phagocytosis. Infect Immun 72, 5322-30 (2004). (Pubitemid 39223420)
38. Houde, M., Gottschalk, M., Gagnon, F., Van Calsteren, M. R. & Segura, M. Streptococcus suis capsular polysaccharide inhibits phagocytosis through destabilization of lipid microdomains and prevents lactosylceramide-dependent recognition. Infect Immun 80, 506-17 (2012).
39. Marques, M. B., Kasper, D. L., Pangburn, M. K. & Wessels, M. R.Prevention ofC3 deposition by capsular polysaccharide is a virulence mechanism of type III group B streptococci. Infect Immun 60, 3986-93 (1992).
40. Ye, C. et al. Clinical, experimental, and genomic differences between intermediately pathogenic, highly pathogenic, and epidemic Streptococcus suis. J Infect Dis 199, 97-107 (2009).
41. Zhao, Y. et al. Role of a type IV-like secretion system of Streptococcus suis 2 in the development of streptococcal toxic shock syndrome. J Infect Dis 204, 274-81 (2011).
42. Feng, Y. et al. Functional definition and global regulation of Zur, a zinc uptake regulatorin a Streptococcus suis serotype 2 strain causing streptococcal toxic shock syndrome. J Bacteriol 190, 7567-78 (2008).
43. Takamatsu, D., Osaki, M & Sekizaki, T. Construction and characterization of Streptococcus suis-Escherichia coli shuttle cloning vectors. Plasmid 45, 101-113 (2001). (Pubitemid 32221956)
44. Warren, L. The thiobarbituric acid assay of sialic acids. J Biol Chem 234, 1971-1975 (1959).
45. Charland N, K. M., Martineau-Doize, B., Jaques, M. & Gottschalk, M. Role of capsule sialic acid in virulence and resistance to phagocytosis of Streptococcus suis capsular type 2. FEMS Immunol Med Microbiol 14, 195-203 (1996). (Pubitemid 26249234)
46. Perez-Casal, J., Price, JA., Maguin, E. & Scott. JR. An M protein with a single C repeat prevents phagocytosis of Streptococcus pyogenes: use of a temperature-sensitive shuttle vector to deliver homologous sequences to the chromosome of S. pyogenes. Mol. Microbiol. 8, 809-819 (1993). (Pubitemid 23171463)
47. Cheon, S. H. et al. Bactericidal activity in whole blood as a potential surrogate marker of immunity after vaccination against tuberculosis. Clin Diagn Lab Immunol 9, 901-7 (2002).
48. Feng, Y. & Cronan, J. E. Overlapping repressor binding sites result in additive regulation of Escherichia coli FadH by FadR and ArcA. J Bacteriol 192, 4289-99 (2010).
49. Feng, Y. & Cronan, J. E. A new member of the Escherichia coli fad regulon: transcriptional regulation of fadM (ybaW). J Bacteriol 191, 6320-8 (2009).
50. Chaffin, D. O., McKinnon, K. & Rubens, C. E. CpsK of Streptococcus agalactiae exhibits alpha2, 3-sialyltransferase activity in Haemophilus ducreyi. Mol Microbiol 45, 109-22 (2002). (Pubitemid 35025937)
51. Lecours, M. P. et al. Sialylation of Streptococcus suis serotype 2 is essential for capsule expression but is not responsible for the main capsular epitope. Microbes Infec 14, 941-50 (2012).