Is ondansetron safe for use during pregnancy?

Canadian Family Physician

Volumn 58, Issue 10, 2012, Pages 1092-1093

  Koren, Gideon ^a  

^a Duchesnay Inc   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DOXYLAMINE PLUS PYRIDOXINE; ONDANSETRON; ANTIEMETIC AGENT;

ARTICLE; CLEFT PALATE; CONGENITAL MALFORMATION; DRUG SAFETY; FIRST TRIMESTER PREGNANCY; FOOD AND DRUG ADMINISTRATION; HUMAN; HYPOKALEMIA; HYPOMAGNESEMIA; META ANALYSIS (TOPIC); NAUSEA AND VOMITING; QT PROLONGATION; SAMPLE SIZE; TORSADE DES POINTES; UNITED STATES; CANADA; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; FEMALE; FETUS; LONG QT SYNDROME; MORNING SICKNESS; NAUSEA; PREGNANCY; PREGNANCY COMPLICATION; VOMITING;

ANTIEMETICS; CANADA; CLEFT PALATE; FEMALE; FETUS; HUMANS; LONG QT SYNDROME; MORNING SICKNESS; NAUSEA; ONDANSETRON; PREGNANCY; PREGNANCY COMPLICATIONS, CARDIOVASCULAR; UNITED STATES; VOMITING;

EID: 84868261913     PISSN: 0008350X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (3)

1. Einarson A, Maltepe C, Navioz Y, Kennedy D, Tan MP, Koren G. The safety of ondansetron for nausea and vomiting of pregnancy: a prospective comparative study. BJOG 2004;111(9):940-3.
2. Anderka M, Mitchell AA, Louik C, Werler MM, Hernández-Diaz S, Rasmussen SA, et al. Medications used to treat nausea and vomiting of pregnancy and the risk of selected birth defects. Birth Defects Res A Clin Mol Teratol 2012;94(1):22-30. Epub 2011 Nov 19.
3. US Food and Drug Administration [website]. FDA drug safety communication: abnormal heart rhythms may be associated with use of Zofran (ondansetron). Silver Spring, MD: US Food and Drug Administration; 2011. Available from: www.fda.gov/Drugs/DrugSafety/ucm271913.htm. Accessed 2012 Aug 23.