Traumatic brain injury in the elderly: Considerations in a series of 103 patients older than 70

Journal of Neurosurgical Sciences

Volumn 56, Issue 3, 2012, Pages 231-237

  Gaetani, P ^a   Revay, M ^a   Sciacca, S ^a   Pessina, F ^a   Aimar, E ^a   Levi, D ^b   Morenghi, E ^a  

^a HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^b Department of Veterinary Medical Sciences   (Switzerland)

Author keywords

Aged; Anticoagulants; Brain injuries; Subarachnoid hemorrhage

Indexed keywords

ACETYLSALICYLIC ACID; CLOPIDOGREL; WARFARIN; ANTITHROMBOCYTIC AGENT; DRUG DERIVATIVE; TICLOPIDINE;

AGED; ANTICOAGULANT THERAPY; ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTUSION; FALLING; FEMALE; GERIATRIC DISORDER; GLASGOW COMA SCALE; HEART ATRIUM FIBRILLATION; HOSPITALIZATION; HUMAN; HYPOTENSION; INTERNATIONAL NORMALIZED RATIO; MAJOR CLINICAL STUDY; MALE; NEUROIMAGING; RETROSPECTIVE STUDY; SUBARACHNOID HEMORRHAGE; SUBDURAL HEMATOMA; TRACHEOTOMY; TRAFFIC ACCIDENT; TRAUMATIC BRAIN INJURY; AGE DISTRIBUTION; BRAIN INJURY; MORBIDITY; MORTALITY; RISK FACTOR; STATISTICS; TREATMENT OUTCOME;

ACCIDENTAL FALLS; AGE DISTRIBUTION; AGED; AGED, 80 AND OVER; BRAIN INJURIES; FEMALE; GLASGOW COMA SCALE; HEMATOMA, SUBDURAL; HUMANS; MALE; MORBIDITY; PLATELET AGGREGATION INHIBITORS; RETROSPECTIVE STUDIES; RISK FACTORS; SUBARACHNOID HEMORRHAGE, TRAUMATIC; TICLOPIDINE; TREATMENT OUTCOME;

EID: 84868259247     PISSN: 03905616     EISSN: 18271855     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Pennings JL, Bachulis BL, Simons CT, Slazinski T. Survival after severe brain injury in the aged. Arch Surg 1993;128:787-93.
2. Vollmer DG, Torner JC, Jane JA, Foulkes MA, Marmarou A, Marshall LF. Age and outcome following traumatic coma: why do older patients fare worse? J Neurosurg 1991;75(Suppl):S37-S49.
3. Kilaru S, Garb J, Emhoff T, Fiallo V, Simon B, Swiencicki T et al. Long-term functional status and mortality of elderly patients with severe closed head injurues. J Trauma 1996;41:957-63. (Pubitemid 26424887)
4. Amacher AL, Bybee DE. Toleration of head injury by the elderly. Neurosurgery 1987;20:954-8. (Pubitemid 17113135)
5. Mosenthal AC, Lavery RF, Addis M, Kaul S, Ross S, Marburger R et al. Isolated traumatic brain injury: age is an independent predictor of mortality and early outcome. J Trauma 2002;52 5.907-11.
6. Kami A, Holtzman R, Bass T, Zorman G, Carter L, Rodriguez L et al. Traumatic head injury in the anticoagulated elderly patient: a lethal combination. Am Surg 2001;67:1098-100. (Pubitemid 33738151)
7. Lavoie A, Ratte S, Cias D, Demers J, Moore L, Martin M et al. Preinjury warfarin use among elderly patients with closed head injuries in a trauma center. J Trauma 2004;56:802-7. (Pubitemid 38534091)
8. Mina AA, Bair HA, Howells GA, Bendick PJ. Complications of preinjury warfarin use in the trauma patient. J Trauma 2003;54:842-7. (Pubitemid 36758794)
9. Ohm C, Mina A, Howells G, Bair H, Bendick P. Effects of antiplatelet agents on outcomes for elderly patients with traumatic intracranial hemorrhage. J Trauma 2005;58:518-22. (Pubitemid 40365811)
10. Morris JA, Mackenzie EJ, Damiano AM, Bass SU. Mortality in trauma patients: the interaction between host factors and severity. J Trauma 1990;30:1476-82.
11. Wojcik R, Cipolle MD, Seislove E, Wasser TE, Pasquale MD. Preinjury warfarin does not impact outcome in trauma patients. J Trauma 2001;51:1147-51.
12. Fortuna GR, Mueller EW, James LE, Shutter LA, Butler KL. The impact of preinjury antiplatelet and anticoagulant pharmacotherapy on outcomes in elderly patients with hemorrhagic brain injury. Surgery 2008;144:598-605.
13. Franko J, Kish KJ, O'Connell BG, Subramanian S, Yuschak JV. Advanced age and preinjury warfarin anticoagulation increase the risk of mortality after head trauma. Advanced age and preinjury warfarin anticoagulation increase the risk of mortality after head trauma. J Trauma 2006;61:107-10.
14. Ahmed N, Bialowas C, Kuo YH, Zawodniak L. Impact of preinjury anticoagulation in patients with traumatic brain injury. South Med J 2009;102 5:476-80.
15. Wojcik R, Cipolle MD, Seislove E, asser TE, Pasquale MD. Preinjury warfarin does not impact outcome in trauma patients. J Trauma 2001;51:1147-51.
16. Williams TM, Sadjadi J, Harken AH, Victorino GP. The necessity to assess anticoagulation status in elderly injured patients. J Trauma 2008;65 4:772-7.
17. Stevens JA, Sogolow ED. Gender differences for non-fatal unintentional fall related injuries among older adults. Inj Prev 2005;11:115-9. (Pubitemid 40576591)
18. Faul M, Xu L, Wald M, Coronado V. Traumatic brain injury in the United States: Emergency Department visits, hospitalizations and deaths 2002-2006. Centers for Disease Control and Prevention, National Center for Injury Prevention and Control: Atlanta; 2010.
19. Inamasu J, Nakatsukasa M, Kuramae T, Nakagawa Y, Miyatake S, Tomiyasu K. Influence of age and anti-platelet/anti-coagulant use on the outcome of elederly patients with fall-related traumatic intracranial hemorrhage. Neurol Med Chir 2010;50:1051-5.