Non-uniform Response to Temozolomide Therapy in a Pituitary Gonadotroph Adenoma

Canadian Journal of Neurological Sciences

Volumn 39, Issue 5, 2012, Pages 683-685

  Ersen, Ayca ^a   Syro, Luis V ^b   Penagos, Luis C ^b   Uribe, Humberto ^c   Scheithauer, Bernd W ^d   Ortiz, Leon D ^e   Rotondo, Fabio ^f   Horvath, Eva ^f   Kovacs, Kalman ^f  

^a DOKUZ EYLUL UNIVERSITY   (Turkey)

^b HOSPITAL PABLO TOBÓN URIBE   (Colombia)

^c Clinica SOMA   (Colombia)

^d MAYO CLINIC   (United States)

^e Section of Neuro oncology   (Colombia)

^f ST MICHAEL'S HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; DACARBAZINE; DNA METHYLTRANSFERASE; DRUG DERIVATIVE; KI 67 ANTIGEN; LUTEINIZING HORMONE; MGMT PROTEIN, HUMAN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; TEMOZOLOMIDE; TUMOR SUPPRESSOR PROTEIN;

ADENOMA; CASE REPORT; DRUG EFFECT; GONADOTROPIN SECRETING CELL; HUMAN; HYPOPHYSIS; HYPOPHYSIS TUMOR; LETTER; MALE; METABOLISM; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY;

ADENOMA; ANTINEOPLASTIC AGENTS, ALKYLATING; DACARBAZINE; DNA MODIFICATION METHYLASES; DNA REPAIR ENZYMES; GONADOTROPHS; HUMANS; KI-67 ANTIGEN; LUTEINIZING HORMONE; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PITUITARY GLAND; PITUITARY NEOPLASMS; TUMOR SUPPRESSOR PROTEINS;

EID: 84868258861     PISSN: 03171671     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0317167100018242     Document Type: Letter

References (5)

1. Heaney, AP. Clinical review: Pituitary carcinoma: difficult diagnosis and treatment. J Clin Endocrinol Metab. 2011; 96(12):3649–60.
2. Ortiz, LD, Syro, LV, Scheithauer, BW, et al. Temozolomide in aggressive pituitary adenomas and carcinomas. Clinics (Sao Paulo). 2012; 67, Suppl 1: 119–23.
3. McCormack, AI, Wass, JA, Grossman, AB. Aggressive pituitary tumours: the role of temozolomide and the assessment of MGMT status Eur J Clin Invest. 2011; 41(10):1133–48.
4. Syro, LV, Uribe, H, Penagos, LC, et al. Antitumour effects of temozolomide in a man with a large, invasive prolactinproducing pituitary neoplasm Clin Endocrinol. 2006; 65(4):552–3.
5. Raverot, G, Sturm, N, de Fraipont, F, et al. Temozolomide treatment in aggressive pituitary tumors and pituitary carcinomas: a French multicenter experience. J Clin Endocrinol Metab. 2010; 95(10):4592–9.