Riccardin D-26, a synthesized macrocyclic bisbibenzyl compound, inhibits human oral squamous carcinoma cells KB and KB/VCR: In vitro and in vivo studies

Biochimica et Biophysica Acta - General Subjects

Volumn 1830, Issue 1, 2013, Pages 2194-2203

  Yue, Bin ^a   Zhao, Cui Rong ^a   Xu, Hui Min ^b   Li, Yuan Yuan ^a   Cheng, Yan Na ^a   Ke, Han Ni ^a   Yuan, Yi ^a   Wang, Rui Qi ^a   Shi, Yan Qiu ^a   Lou, Hong Xiang ^a   Qu, Xian Jun ^a  

^a SHANDONG UNIVERSITY   (China)

^b QINGDAO UNIVERSITY   (China)

Author keywords

KB VCR; MAPK; MDR; Mitochondria mediated intrinsic apoptosis pathway; PI3K Akt; Synthesized macrocyclic bisbibenzyl compound

Indexed keywords

BIBENZYL DERIVATIVE; MACROCYCLIC COMPOUND; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PLACEBO; PROTEIN KINASE B; RICCARDIN D 26; UNCLASSIFIED DRUG; VINCRISTINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CHEMOTHERAPY; CANCER GROWTH; CANCER INHIBITION; CELL VIABILITY; DRUG EFFICACY; DRUG SCREENING; DRUG SENSITIVITY; DRUG SYNTHESIS; ENZYME INHIBITION; ENZYME REGULATION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; MOUTH SQUAMOUS CELL CARCINOMA; NONHUMAN; PRIORITY JOURNAL; TREATMENT DURATION; TREATMENT RESPONSE; TUMOR VOLUME; TUMOR XENOGRAFT;

ANIMALS; ANNEXIN A5; ANTINEOPLASTIC AGENTS; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; DRUG RESISTANCE, NEOPLASM; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; MACROCYCLIC COMPOUNDS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, NUDE; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; MOUTH NEOPLASMS; PHENYL ETHERS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; STILBENES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MUS; MUS MUSCULUS;

EID: 84868248479     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2012.10.011     Document Type: Article

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