The sigma-1 receptor binds to the Nav1.5 voltage-gated Na+ channel with 4-fold symmetry

Journal of Biological Chemistry

Volumn 287, Issue 44, 2012, Pages 37021-37029

  Balasuriya, Dilshan ^a   Stewart, Andrew P ^a   Crottès, David ^b   Borgese, Franck ^b   Soriani, Olivier ^b   Edwardson, J Michael ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b CENTRE DE BIOCHIMIE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ATOMIC FORCE; ION CHANNEL; RECEPTOR BINDING SITE; TRANSMEMBRANE REGIONS;

BIOCHEMISTRY; BIOLOGY;

ATOMIC FORCE MICROSCOPY;

HALOPERIDOL; PENTAZOCINE; SIGMA 1 OPIATE RECEPTOR; SODIUM CHANNEL NAV1.5;

ACTION POTENTIAL; ARTICLE; BINDING SITE; BREAST CANCER; CANCER CELL; CANCER INVASION; CELL DISRUPTION; COMPLEX FORMATION; CONTROLLED STUDY; GENETIC TRANSFECTION; HEART MUSCLE CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN ISOLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RECEPTOR BINDING; RECEPTOR BLOCKING;

CELL LINE; CHROMATOGRAPHY, AFFINITY; GENE KNOCKDOWN TECHNIQUES; HALOPERIDOL; HUMANS; LIGANDS; MEMBRANE POTENTIALS; MICROSCOPY, ATOMIC FORCE; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL; PENTAZOCINE; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; RECEPTORS, SIGMA; RNA INTERFERENCE; SINGLE-CELL ANALYSIS;

EID: 84868241887     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.382077     Document Type: Article

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